Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Ronald M. Lynch"'
Autor:
Courtney B. Lagarde, Kapil Thapa, Nicole M. Cullen, Mackenzie L. Hawes, Khudeja Salim, Megan C. Benz, Sophie R. Dietrich, Brandon E. Burow, Bruce A. Bunnell, Elizabeth C. Martin, Bridgette M. Collins-Burow, Ronald M. Lynch, Van T. Hoang, Matthew E. Burow, Jennifer S. Fang
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
At the time of breast cancer diagnosis, most patients meet the diagnostic criteria to be classified as obese or overweight. This can significantly impact patient outcome: breast cancer patients with obesity (body mass index > 30) have a poorer progno
Externí odkaz:
https://doaj.org/article/8c40480bd5c346848422b3c98f3422ce
Autor:
Catherine Min, Jean-Philippe Galons, Ronald M. Lynch, Leah V. Steyn, Nicholas D. Price, Brad P. Weegman, Michael J. Taylor, Abhishek Pandey, Robert Harland, Diego Martin, David Besselsen, Charles W. Putnam, Klearchos K. Papas
Publikováno v:
Frontiers in Transplantation, Vol 3 (2024)
IntroductionTransplantation of kidneys from expanded criteria donors (ECD), including after circulatory death (DCD), is associated with a higher risk of adverse events compared to kidneys from standard criteria donors. In previous studies, improvemen
Externí odkaz:
https://doaj.org/article/5ecff4219fa1444483f23269e6180e51
Autor:
Alexander L. Pendleton, Stephanie R. Wesolowski, Timothy R. H. Regnault, Ronald M. Lynch, Sean W. Limesand
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Intrauterine growth restriction (IUGR) of the fetus, resulting from placental insufficiency (PI), is characterized by low fetal oxygen and nutrient concentrations that stunt growth rates of metabolic organs. Numerous animal models of IUGR recapitulat
Externí odkaz:
https://doaj.org/article/fb182e110b44438d8eb08377868b43c6
Publikováno v:
Micromachines, Vol 10, Iss 8, p 533 (2019)
Lung-on-a-chip (LoC) models hold the potential to rapidly change the landscape for pulmonary drug screening and therapy, giving patients more advanced and less invasive treatment options. Understanding the drug absorption in these microphysiological
Externí odkaz:
https://doaj.org/article/f7138a75d176418b820e228c834600ee
Autor:
Robert J. Gillies, Victor J. Hruby, Eugene A. Mash, Haiyong Han, Brenda Baggett, David L. Morse, Ronald M. Lynch, Jatinder Josan, Josef Vagner, Liping Xu
A novel approach to specifically target tumor cells for detection and treatment is the proposed use of heteromultivalent ligands, which are designed to interact with, and noncovalently crosslink, multiple different cell surface receptors. Although en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f12fcb85ef528fa8bcaa799d7065c11
https://doi.org/10.1158/1535-7163.c.6531459
https://doi.org/10.1158/1535-7163.c.6531459
Autor:
Robert J. Gillies, Victor J. Hruby, Eugene A. Mash, Haiyong Han, Brenda Baggett, David L. Morse, Ronald M. Lynch, Jatinder Josan, Josef Vagner, Liping Xu
Supplementary Figures 1-6 from Enhanced targeting with heterobivalent ligands
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1998e4e68b92bc782904b5e3e98f64ac
https://doi.org/10.1158/1535-7163.22484562.v1
https://doi.org/10.1158/1535-7163.22484562.v1
Autor:
Leah V. Steyn, Nathaniel J. Hart, Klearchos K. Papas, Emily Harnois, Cyonna Gibson, Nicholas D. Price, Madison Schultz, Alma Banuelos, Ronald M. Lynch, Barry Huey, Craig Weber
Publikováno v:
Am J Physiol Cell Physiol
The islets of Langerhans of the pancreas are the primary endocrine organ responsible for regulating whole body glucose homeostasis. The use of isolated primary islets for research development and training requires organ resection, careful digestion,
Autor:
Sean W. Limesand, Andrew T. Antolic, Amy C. Kelly, Kevin Doubleday, Alexander L. Pendleton, Miranda J. Anderson, Ronald M. Lynch, Leticia E. Camacho, Paul R. Langlais, Melissa A. Davis
Publikováno v:
Am J Physiol Endocrinol Metab
Fetal sheep with placental insufficiency-induced intrauterine growth restriction (IUGR) have lower hindlimb oxygen consumption rates (OCRs), indicating depressed mitochondrial oxidative phosphorylation capacity in their skeletal muscle. We hypothesiz
Autor:
Sean W. Limesand, Ronald M. Lynch, Stephanie R. Wesolowski, Alexander L. Pendleton, Timothy R. H. Regnault
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Frontiers in Endocrinology
Paediatrics Publications
Frontiers in Endocrinology
Paediatrics Publications
Intrauterine growth restriction (IUGR) of the fetus, resulting from placental insufficiency (PI), is characterized by low fetal oxygen and nutrient concentrations that stunt growth rates of metabolic organs. Numerous animal models of IUGR recapitulat
Autor:
Sean W. Limesand, Nathaniel J. Hart, Josef Vagner, Klearchos K. Papas, Craig Weber, Ronald M. Lynch
Publikováno v:
American Journal of Physiology-Cell Physiology. 316:C48-C56
Linking two pharmacophores that bind different cell surface receptors into a single molecule can enhance cell-targeting specificity to cells that express the complementary receptor pair. In this report, we developed and tested a synthetic multivalent