Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Ronald L. Schnaar"'
Autor:
Dong Won Kim, Kevin J. Tu, Alice Wei, Ashley J. Lau, Anabel Gonzalez-Gil, Tianyu Cao, Kerstin Braunstein, Jonathan P. Ling, Juan C. Troncoso, Philip C. Wong, Seth Blackshaw, Ronald L. Schnaar, Tong Li
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-23 (2022)
Abstract Background Amongst risk alleles associated with late-onset Alzheimer’s disease (AD), those that converged on the regulation of microglia activity have emerged as central to disease progression. Yet, how canonical amyloid-β (Aβ) and tau p
Externí odkaz:
https://doaj.org/article/ec442a6e4b7a4771a917c198f063d4ef
Autor:
Senka Blažetić, Vinko Krajina, Irena Labak, Barbara Viljetić, Valentina Pavić, Vedrana Ivić, Marta Balog, Ronald L. Schnaar, Marija Heffer
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17218 (2023)
Gangliosides are major glycans on vertebrate nerve cells, and their metabolic disruption results in congenital disorders with marked cognitive and motor deficits. The sialyltransferase gene St3gal2 is responsible for terminal sialylation of two promi
Externí odkaz:
https://doaj.org/article/d075e5a3043442f093c685158832301a
Autor:
Tanya R. McKitrick, Margaret E. Ackerman, Robert M. Anthony, Clay S. Bennett, Michael Demetriou, Gregory A. Hudalla, Katharina Ribbeck, Stefan Ruhl, Christina M. Woo, Loretta Yang, Seth J. Zost, Ronald L. Schnaar, Tamara L. Doering
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Advances in experimental capabilities in the glycosciences offer expanding opportunities for discovery in the broad areas of immunology and microbiology. These two disciplines overlap when microbial infection stimulates host immune responses and glyc
Externí odkaz:
https://doaj.org/article/3000e7b4d667473fbab845be76c82ed3
Autor:
Hongmei Liu, Yu Zheng, Yingxian Zhang, Jin Li, Steve M. Fernandes, Dongfeng Zeng, Xiaohui Li, Ronald L. Schnaar, Yi Jia
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 122, Iss , Pp - (2020)
Aims: Siglec-E, the mouse ortholog of human Siglec-9, is an immunosuppressive cell surface receptor. Both Siglec-E and Siglec-9 are primarily found on neutrophils, macrophages, and monocytes. When Siglec-E binds to sialoglycan ligands in its extracel
Externí odkaz:
https://doaj.org/article/6eaa8c170d9849d284f60805a82ac413
Autor:
Katarina Ilic, Xiao Lin, Ayse Malci, Mario Stojanović, Borna Puljko, Marko Rožman, Željka Vukelić, Marija Heffer, Dirk Montag, Ronald L. Schnaar, Svjetlana Kalanj-Bognar, Rodrigo Herrera-Molina, Kristina Mlinac-Jerkovic
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13590 (2021)
The recent identification of plasma membrane (Ca2+)-ATPase (PMCA)-Neuroplastin (Np) complexes has renewed attention on cell regulation of cytosolic calcium extrusion, which is of particular relevance in neurons. Here, we tested the hypothesis that PM
Externí odkaz:
https://doaj.org/article/5cc0b27adccb44a6adb9541d0650f7f1
Autor:
Anabel Gonzalez-Gil, Ronald L. Schnaar
Publikováno v:
Cells, Vol 10, Iss 5, p 1260 (2021)
A dense and diverse array of glycans on glycoproteins and glycolipids decorate all cell surfaces. In vertebrates, many of these carry sialic acid, in a variety of linkages and glycan contexts, as their outermost sugar moiety. Among their functions, g
Externí odkaz:
https://doaj.org/article/4ca1b67ff9c94aff8494654b531d3a0d
Autor:
Yadong Wei, Krishan D. Chhiba, Fengrui Zhang, Xujun Ye, Lihui Wang, Li Zhang, Piper A. Robida, Liliana Moreno-Vinasco, Ronald L. Schnaar, Axel Roers, Karin Hartmann, Chang-Min Lee, Delia Demers, Tao Zheng, Bruce S. Bochner, Zhou Zhu
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 1, p 19 (2018)
Sialic acid-binding Ig-like lectin 8 (Siglec-8) is expressed on the surface of human eosinophils, mast cells, and basophils—cells that participate in allergic and other diseases. Ligation of Siglec-8 by specific glycan ligands or antibodies trigger
Externí odkaz:
https://doaj.org/article/0914fd126b25401b9b3e7e0edac429f7
Autor:
Jonathan P. Schneck, Mathias Oelke, Christian Kurts, Moriya Tsuji, Ronald L. Schnaar, Christoph Heuser, Pablo H.H. Lopez, Robert L. Giuntoli, Xiangming Li, Tonya J. Webb
PDF file - 225K, Schematic of Ganglioside GD3 and other glycolipids used or referred to in this paper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a16e1f594710df302e177cd90b1c77
https://doi.org/10.1158/0008-5472.22392759.v1
https://doi.org/10.1158/0008-5472.22392759.v1
Autor:
Anabel Gonzalez-Gil, Ronald L. Schnaar
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b4e6a9da26ac5a028cda9223ba8d311
https://doi.org/10.1016/b978-0-12-821618-7.00007-9
https://doi.org/10.1016/b978-0-12-821618-7.00007-9
Publikováno v:
Molecular aspects of medicine.
Most human Siglecs (sialic acid binding immunoglobulin-like lectins) are expressed on the surfaces of overlapping subsets of immune cells, and most carry immunoreceptor tyrosine-based inhibitory domains on their intracellular motifs. When immune inhi