Zobrazeno 1 - 10
of 373
pro vyhledávání: '"Ronald L Hayes"'
Autor:
Olena Y Glushakova, Andriy A Glushakov, Dayanjan S Wijesinghe, Alex B Valadka, Ronald L Hayes, Alexander V Glushakov
Publikováno v:
Brain Circulation, Vol 3, Iss 2, Pp 87-108 (2017)
Acute brain injuries, including ischemic and hemorrhagic stroke, as well as traumatic brain injury (TBI), are major worldwide health concerns with very limited options for effective diagnosis and treatment. Stroke and TBI pose an increased risk for t
Externí odkaz:
https://doaj.org/article/6a3094cf3fc849709d7f0083d4bbce64
Publikováno v:
Brain Circulation, Vol 2, Iss 1, Pp 28-47 (2016)
The effectiveness of current management of critically ill stroke patients depends on rapid assessment of the type of stroke, ischemic or hemorrhagic, and on a patient′s general clinical status. Thrombolytic therapy with recombinant tissue plasminog
Externí odkaz:
https://doaj.org/article/2057f60468834a6faaf56658a8c9e1eb
Publikováno v:
Brain Circulation, Vol 2, Iss 3, Pp 129-132 (2016)
As traumatic brain injury (TBI) continues to affect children and young adults worldwide, research on reliable biomarkers grows as a possible aid in determining the severity of injury. However, many studies have revealed that diverse biomarkers such a
Externí odkaz:
https://doaj.org/article/139089c814174ca391947b43d8ef1afe
Autor:
Firas H Kobeissy, Joy D Guingab-Cagmat, Zhiqun Zhang, Ahmed Moghieb, Olena Y Glushakova, Stefania Mondello, Angela M. Boutte, John Anagli, Richard Rubenstein, Hisham Bahmad, Amy K. Wagner, Ronald L Hayes, Kevin K W Wang
Publikováno v:
Frontiers in Neurology, Vol 7 (2016)
Traumatic brain injury (TBI) represents a critical health problem of which diagnosis, management and treatment remain challenging. TBI is a contributing factor in approximately 1/3 of all injury-related deaths in the United States. The Centers for Di
Externí odkaz:
https://doaj.org/article/7dbcdf19363b4e20a290f30c44c0b66a
Autor:
Martha V. Douglas-Escobar, Shelley C. Heaton, Jeffrey Allan Bennett, Linda J Young, Olena eGlushakova, Xiaohui eXu, Daphna Yasova Barbeau, Candice eRossignol, Cindy eMiller, Alissa M Old Crow, Ronald L Hayes, Michael D. Weiss
Publikováno v:
Frontiers in Neurology, Vol 5 (2014)
Objective - We examined two potential biomarkers of brain damage in HIE neonates: glial fibrillary acidic protein (GFAP; a marker of gliosis) and ubiquitin C-terminal hydrolase L1 (UCH-L1; a marker of neuronal injury). We hypothesized the biomarkers
Externí odkaz:
https://doaj.org/article/7e9bc58b58ce4ed28b986ffec75577a4
Publikováno v:
Frontiers in Neurology, Vol 4 (2013)
Traumatic brain injury (TBI) is a major medical crisis without any FDA-approved pharmacological therapies that have been demonstrated to improve functional outcomes. It has been argued that discovery of disease-relevant biomarkers might help to guide
Externí odkaz:
https://doaj.org/article/b52706ac7864408dbfc54cf0ca06ddc1
Autor:
Stanislav I. Svetlov, Victor ePrima, Olena eGlushakova, Artem eSvetlov, Daniel eKirk, Hector eGutierrez, Victor eSerebruany, Kenneth eCurley, Kevin K W Wang, Ronald L Hayes
Publikováno v:
Frontiers in Neurology, Vol 3 (2012)
A number of experimental models of blast brain injury have been implemented in rodents and larger animals. However, the variety of blast sources and the complexity of blast wave biophysics have made data on injury mechanisms and biomarkers difficult
Externí odkaz:
https://doaj.org/article/ec6ca0206b3d4c3d8efc13c9e7555e0d
Publikováno v:
ASN Neuro, Vol 3 (2010)
Axonally specific microtubule-associated protein tau is an important component of neurofibrillary tangles found in AD (Alzheimer's disease) and other tauopathy diseases such as CTE (chronic traumatic encephalopathy). Such tau aggregate is found to be
Externí odkaz:
https://doaj.org/article/66db47f6af1e46028f645dd1e1eb296e
Autor:
Rita Formisano, Mariagrazia D’Ippolito, Marco Giustini, Sheila Catani, Stefania Mondello, Iliana Piccolino, Filomena Iannuzzi, Kevin K. Wang, Ronald L. Hayes
Publikováno v:
Brain Sciences, Vol 14, Iss 3, p 239 (2024)
Introduction: Serum biomarkers, such as Neurofilament Light (NF-L), Glial Fibrillary Acidic Protein (GFAP), Ubiquitin C-terminal Hydrolase (UCH-L1), and Total-tau (T-Tau) have been proposed for outcome prediction in the acute phase of severe traumati
Externí odkaz:
https://doaj.org/article/9d115c3d21dd41f490803e9b9eae63eb
Autor:
Zhihui Yang, Seza Apiliogullari, Yueqiang Fu, Ayah Istanbouli, Sehajpreet Kaur, Iktej Singh Jabbal, Ahmed Moghieb, Zoha Irfan, Robert Logan Patterson, Milin Kurup, Lindsey Morrow, Michael Cohn, Zhiqun Zhang, Jiepei Zhu, Ronald L. Hayes, Helen M. Bramlett, M. Ross Bullock, W. Dalton Dietrich, Michael Y. Wang, Firas Kobeissy, Kevin W. Wang
Publikováno v:
Diagnostics, Vol 13, Iss 10, p 1814 (2023)
Acute traumatic spinal cord injury (SCI) is recognized as a global problem that can lead to a range of acute and secondary complications impacting morbidity and mortality. There is still a lack of reliable diagnostic and prognostic biomarkers in pati
Externí odkaz:
https://doaj.org/article/422f74293f6740d2a6ac90eff89d2d2c