Výsledky vyhledávání - "Ronald L, Luitwieler"

Cerebrospinal-fluid-derived Immunoglobulin G of Different Multiple Sclerosis Patients Shares Mutated Sequences in Complementarity Determining Regions

Autor: Martijn M. van Duijn, Theo M. Luider, Karim L. Kreft, Ronald L. Luitwieler, Vaibhav Singh, Christoph Stingl, Lennard J. M. Dekker, R Q Hintzen, Marcel P. Stoop

Publikováno v: Molecular & Cellular Proteomics, 12(12), 3924-3934. American Society for Biochemistry and Molecular Biology Inc.

B lymphocytes play a pivotal role in multiple sclerosis pathology, possibly via both antibody-dependent and -independent pathways. Intrathecal immunoglobulin G in multiple sclerosis is produced by clonally expanded B-cell populations. Recent studies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a445845bc9a3386c4ffb3b3ad6a6f3
https://doi.org/10.1074/mcp.M113.030346

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Central memory CD4+ T cells dominate the normal cerebrospinal fluid

Autor: Chris van Velzen, Jaco Kraan, Peter A. E. Sillevis Smitt, Patricia D. M. van den Broek, Ronald L. Luitwieler, Jan W. Gratama, Marieke T. de Graaf

Publikováno v: Cytometry Part B-Clinical Cytometry, 80B(1), 43-50. Wiley-Liss Inc.

Background: To use cerebrospinal fluid (CSF) immune phenotyping as a diagnostic and research tool, we have set out to establish reference values of white blood cell (WBC) subsets in CSF. Methods: We assessed the absolute numbers and percentages of WB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7423593d4b01fcf2a2499c9acd06471c
https://doi.org/10.1002/cyto.b.20542

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Quantitative Proteomics and Metabolomics Analysis of Normal Human Cerebrospinal Fluid Samples

Autor: Marcel P. Stoop, Leon Coulier, Therese Rosenling, Shanna Shi, Agnieszka M. Smolinska, Lutgarde Buydens, Kirsten Ampt, Christoph Stingl, Adrie Dane, Bas Muilwijk, Ronald L. Luitwieler, Peter A.E. Sillevis Smitt, Rogier Q. Hintzen, Rainer Bischoff, Sybren S. Wijmenga, Thomas Hankemeier, Alain J. van Gool, Theo M. Luider

Publikováno v: Molecular & Cellular Proteomics, 9, 2063-2075
Molecular & Cellular Proteomics, 9, 9, pp. 2063-2075
Molecular & Cellular Proteomics, 9(9), 2063-2075. American Society for Biochemistry and Molecular Biology Inc.
Molecular & Cellular Proteomics, 9(9), 2063-2075. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Molecular and Cellular Proteomics, 9, 9, 2063-2075

The analysis of cerebrospinal fluid (CSF) is used in biomarker discovery studies for various neurodegenerative central nervous system (CNS) disorders. However, little is known about variation of CSF proteins and metabolites between patients without n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa1a48ca07c68ca915885fe9785baaa
https://doi.org/10.1074/mcp.m110.000877

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Addition of serum-containing medium to cerebrospinal fluid prevents cellular loss over time

Autor: Ronald L. Luitwieler, Jaco Kraan, Patricia D. M. van den Broek, Jan W. Gratama, Marieke T. de Graaf, Martin J. van den Bent, Peter A. E. Sillevis Smitt, Paul I.M. Schmitz, Joke G. Boonstra

Publikováno v: Journal of Neurology, 258(8), 1507-1512. D. Steinkopff-Verlag
Journal of Neurology

Immediately after sampling, leukocyte counts in native cerebrospinal fluid (CSF) start to decrease rapidly. As the time lapse between CSF collection to analysis is not routinely registered, the clinical significance of decreasing cell counts in nativ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4fd7104a733ee2d02758f5d94b6ccd4
https://pure.eur.nl/en/publications/6cbf3fb1-16b2-4e92-bed7-b43227aca503

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[Antidote against local anaesthetic intoxication: new use of lipid emulsion for intravenous administration]

Autor: Maarten, ter Horst, Gilbert C H, Tjiang, Ronald L, Luitwieler, Chris, van Velzen, Robert Jan, Stolker, Marcel, de Quelerij

Publikováno v: Nederlands tijdschrift voor geneeskunde. 154

Local anaesthetics are routinely used for several indications, but despite local administration their use may lead to systemic toxicity. The symptoms include numbness of the tongue, dizziness, tinnitus, visual disturbances, muscle spasms, convulsions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd08e0eed57f70e7f48f5b8ce54eed0e
https://pubmed.ncbi.nlm.nih.gov/20977791

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