The antimicrobial and osteoinductive properties of silver nanoparticle/poly (dl-lactic-co-glycolic acid)-coated stainless steel

Autor: Kevin S. Lee, Doug Carpenter, Zhong Zheng, Yi Liu, Chunling Wang, Ching Yun Hsu, Janette N. Zara, Ronald K. Siu, Lloyd S. Miller, Kang Ting, Xinli Zhang, Chia Soo, Donnalisa E. Soofer

Publikováno v: Biomaterials. 33:8745-8756

Implant-associated bacterial infections are one of the most serious complications in orthopedic surgery. Treatment of these infections often requires multiple operations, device removal, long-term systemic antibiotics, and extended rehabilitation, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32a8fcb1351b6e6a97d4353f8b8d46e
https://doi.org/10.1016/j.biomaterials.2012.08.010

Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells

Autor: Dorota Kurek, Tim Blauwkamp, Wouter Koole, Ronald K. Siu, Alex Maas, Roel Nusse, Elif Eroglu, Derk ten Berge

Publikováno v: Nature Cell Biology, 13(9), 1070-U88. Nature Publishing Group

Pluripotent stem cells exist in naive and primed states, epitomized by mouse embryonic stem cells (ESCs) and the developmentally more advanced epiblast stem cells (EpiSCs; ref. 1). In the naive state of ESCs, the genome has an unusual open conformati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f47bbc2be89a26029c27460ee6c3bb
https://doi.org/10.1038/ncb2314

The Role of NELL-1, a Growth Factor Associated with Craniosynostosis, in Promoting Bone Regeneration

Autor: Kang Ting, Ronald K. Siu, Janette N. Zara, Xinli Zhang, Chia Soo

Publikováno v: Journal of Dental Research. 89:865-878

Efforts to enhance bone regeneration in orthopedic and dental cases have grown steadily for the past decade, in line with increasingly sophisticated regenerative medicine. To meet the unprecedented demand for novel osteospecific growth factors with f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c79412a5b9eb1e73c615fa12d0ac96d
https://doi.org/10.1177/0022034510376401

Novel Wnt Regulator NEL-Like Molecule-1 Antagonizes Adipogenesis and Augments Osteogenesis Induced by Bone Morphogenetic Protein 2

Autor: Janette N. Zara, Kevin S. Lee, Chia Soo, Kevork Khadarian, Sotirios Tetradis, Aaron W. James, Ronald K. Siu, Kang Ting, Jia Shen, Michael F. Chiang, Alan Nguyen, Shen Pang, Min Lee, Xinli Zhang, Greg Asatrian

Publikováno v: The American journal of pathology. 186(2)

The differentiation factor NEL-like molecule-1 (NELL-1) has been reported as osteoinductive in multiple in vivo preclinical models. Bone morphogenetic protein (BMP)-2 is used clinically for skeletal repair, but in vivo administration can induce abnor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a174ddcae9a420582aedbd5373cd18
https://pubmed.ncbi.nlm.nih.gov/26772960

Use of human perivascular stem cells for bone regeneration

Autor: Bruno Péault, Ronald K. Siu, Min Lee, Wei Yuan, Aaron W. James, Chia Soo, Asal Askarinam, Kang Ting, Victoria Scott, Virginia Nguyen, Raghav Goyal, Janette N. Zara, Mirko Corselli, Michael F. Chiang

Publikováno v: James, A W, Zara, J N, Corselli, M, Chiang, M, Yuan, W, Nguyen, V, Askarinam, A, Goyal, R, Siu, R K, Scott, V, Lee, M, Ting, K, Péault, B & Soo, C 2012, ' Use of human perivascular stem cells for bone regeneration ', Journal of Visualized Experiments (JoVE), no. 63, pp. e2952 . https://doi.org/10.3791/2952
Journal of Visualized Experiments : JoVE

Human perivascular stem cells (PSCs) can be isolated in sufficient numbers from multiple tissues for purposes of skeletal tissue engineering1-3. PSCs are a FACS-sorted population of 'pericytes' (CD146+CD34-CD45-) and 'adventitial cells' (CD146-CD34+C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509acc2f40a30edc2d5bce5470c3b102
https://hdl.handle.net/20.500.11820/6f98de61-219e-4ce6-9589-b40813a8d75f