Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ronald K. Gary"'
Autor:
Taylor M. Gerson, Audrey M. Ott, Monika M. A. Karney, Jillian N. Socea, Daren R. Ginete, Lakshminarayan M. Iyer, L. Aravind, Ronald K. Gary, Helen J. Wing
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT The VirB protein, encoded by the large virulence plasmid of Shigella spp., is a key transcriptional regulator of virulence genes. Without virB, Shigella cells are avirulent. On the virulence plasmid, VirB functions to offset transcriptional
Externí odkaz:
https://doaj.org/article/fc3cc248550549869b8473588cb9be2a
Publikováno v:
Biology Open, Vol 7, Iss 1 (2018)
Lithium salt is a classic glycogen synthase kinase 3 (GSK3) inhibitor. Beryllium is a structurally related inhibitor that is more potent but relatively uncharacterized. This study examined the effects of these inhibitors on the phosphorylation of end
Externí odkaz:
https://doaj.org/article/f70419532539436fa2fd220c6783af3c
Autor:
Taylor M. Gerson, Audrey M. Ott, Monika MA. Karney, Jillian N. Socea, Daren R. Ginete, Lakshminarayan M. Iyer, L. Aravind, Ronald K. Gary, Helen J. Wing
Publikováno v:
bioRxiv
The VirB protein, encoded by the large virulence plasmid ofShigellaspp., is a key transcriptional regulator of virulence genes. Without a functionalvirBgene,Shigellacells are avirulent. On the virulence plasmid, VirB functions to offset transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae88ee8e7e491f684d5593973b40c9f7
https://doi.org/10.1101/2023.05.16.541010
https://doi.org/10.1101/2023.05.16.541010
Autor:
Rebecca C. Lim, Ronald K. Gary
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11fdde3236a707e09fbf6ca5ad533e76
https://doi.org/10.1096/fasebj.2022.36.s1.r4056
https://doi.org/10.1096/fasebj.2022.36.s1.r4056
Publikováno v:
Preparative Biochemistry & Biotechnology. 50:585-591
Beryllium ion elicits p53-mediated cell cycle arrest in some types of human cancer cells, and it is a potent inhibitor of GSK3 kinase activity. Paradoxically, Be2+ is regarded to have almost neglig...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8cbefdbc02fd60a0f71701049a670db
https://doi.org/10.1080/10826068.2020.1719514
https://doi.org/10.1080/10826068.2020.1719514
Publikováno v:
Cell Proliferation. 49:698-709
Objectives Beryllium salts (here, beryllium sulphate) can produce a cytostatic effect in some cell types. The basis for this effect may include increased expression of proliferation inhibitors, reduced expression of proliferation promoters, or both.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c0f27408ae2ec6fe97f8e13018403ab
https://doi.org/10.1111/cpr.12291
https://doi.org/10.1111/cpr.12291
Autor:
Bhagya De Silva, Ronald K. Gary
Publikováno v:
The FASEB Journal. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::198fb6204ad25e0e98856c736ebe2660
https://doi.org/10.1096/fasebj.2018.32.1_supplement.652.38
https://doi.org/10.1096/fasebj.2018.32.1_supplement.652.38
Autor:
Derek A. Jensen, Ronald K. Gary
Publikováno v:
Journal of Chromatography A. 1417:21-29
Reliable HPLC methods are available to estimate octanol-water partition coefficients, but there is no comparable method for alkane-water partition coefficients that is accurate and applicable across a broad span of logP(alk). This study describes a h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab159888bfc7f55bab2f005ea075473a
https://doi.org/10.1016/j.chroma.2015.09.020
https://doi.org/10.1016/j.chroma.2015.09.020
Publikováno v:
BioMetals. 27:1203-1216
Glycogen synthase kinase 3β (GSK-3β) is a key regulator in signaling networks that control cell proliferation, metabolism, development, and other processes. Lithium chloride is a GSK-3 family inhibitor that has been a mainstay of in vitro and in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d9fc90f327067894eee69b214e36324
https://doi.org/10.1007/s10534-014-9783-y
https://doi.org/10.1007/s10534-014-9783-y
Autor:
Joseph Lombardo, Jeffrey L. Cummings, Kate Zhong, Ronald K. Gary, Jefferson W. Kinney, Sarah J. Banks, Ryan R. Walsh
Publikováno v:
CNS Spectrums. 18:128-138
Alzheimer's disease (AD) is an urgent public health challenge that is rapidly approaching epidemic proportions. New therapies that defer or prevent the onset, delay the decline, or improve the symptoms are urgently needed. All phase 3 drug developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb315e2d572f846f9df613b55b55cd6
https://doi.org/10.1017/s1092852913000023
https://doi.org/10.1017/s1092852913000023