Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ronald J. Tomek"'
Autor:
Bruce A. Roe, Nancy J. Zeleznik-Le, Ronald J. Tomek, Reiner Strick, Janet D. Rowley, Pamela L. Strissel
Publikováno v:
Human Molecular Genetics. 9:1671-1679
The human AF9 gene at 9p22 is one of the most common fusion partner genes with the MLL gene at 11q23, resulting in the t(9;11)(p22;q23). The MLL-AF9 fusion gene is associated with de novo acute myelo-genous leukemia (AML), rarely with acute lymphocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f865def328a0c77c2de437b905f19f
https://doi.org/10.1093/hmg/9.11.1671
https://doi.org/10.1093/hmg/9.11.1671
Autor:
A Harden, Janet D. Rowley, Nancy J. Zeleznik-Le, Y Suto, Stephen D. Smith, R. J. Allen, M M Le Beau, L Giordano, Christine Vignon, R. L. Moldwin, Thomas Ried, Richard A. Larson, M M Lu, Ronald J. Tomek, T Veldman
Publikováno v:
Scopus-Elsevier
A new cell line with megakaryoblastic features, designated UoC-M1, was established from the malignant cells of a 68-year-old patient with acute myeloid leukemia. The patient's leukemic cells reacted with alpha-naphthyl acetate esterase and acid phosp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::940b073702ebba7f1a58bc0ca45508b9
https://doi.org/10.1038/sj.leu.2401002
https://doi.org/10.1038/sj.leu.2401002
Autor:
Janet D. Rowley, David E. Housman, Olatoyosi M. Sobulo, Nancy J. Zeleznik-Le, Shalini C. Reshmi, Ronald J. Tomek, Julian Borrow, A Harden, Norman A. Doggett, Brigitte Schlegelberger
Publikováno v:
Proceedings of the National Academy of Sciences. 94:8732-8737
The recurring translocation t(11;16)(q23;p13.3) has been documented only in cases of acute leukemia or myelodysplasia secondary to therapy with drugs targeting DNA topoisomerase II. We show that the MLL gene is fused to the gene that codes for CBP (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ea45639aa2606fa4048cabc3b52aad
https://doi.org/10.1073/pnas.94.16.8732
https://doi.org/10.1073/pnas.94.16.8732
Publikováno v:
Proceedings of the National Academy of Sciences. 88:795-799
Cardiac fibroblasts are mainly responsible for the synthesis of major extracellular matrix proteins in the heart, including fibrillar collagen types I and III and fibronectin. In this report we show that these cells, when stimulated by transforming g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ef648cb5e7a62371c6da40cc7e07c8
https://doi.org/10.1073/pnas.88.3.795
https://doi.org/10.1073/pnas.88.3.795
Publikováno v:
Molecular and cellular biochemistry. 136(2)
Cardiac fibroblasts that reside in the interstitium are the cellular origin of collagen and other proteins of the extracellular matrix in the heart. We have previously shown thatin vitro gene expression, proliferation and even phenotypic features of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e654dc4b7e419fe4149e79edd3b548
https://pubmed.ncbi.nlm.nih.gov/7845372
https://pubmed.ncbi.nlm.nih.gov/7845372
Publikováno v:
Journal of molecular and cellular cardiology. 26(2)
Sex-related differences in predisposition to heart diseases have long been recognized. The molecular and cellular bases for this difference are unknown. In this study we have compared expression of genes for various structural and functional proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c029d926c251042e31a88a290629ee
https://pubmed.ncbi.nlm.nih.gov/8006987
https://pubmed.ncbi.nlm.nih.gov/8006987