Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Ronald J. Marler"'
Autor:
Sandra J. Gendler, Peter A. Cohen, Jonathan A. Leighton, Ronald J. Marler, Jessica E. Gorman, Cathy S. Madsen, Tze Wei Poh
Supplementary figure legends -PDF file 60K, Supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ef8eb7042eb03f76f100159e4d1887
https://doi.org/10.1158/1078-0432.22451321
https://doi.org/10.1158/1078-0432.22451321
Autor:
Sandra J. Gendler, Peter A. Cohen, Jonathan A. Leighton, Ronald J. Marler, Jessica E. Gorman, Cathy S. Madsen, Tze Wei Poh
Purpose: MUC1 is a tumor-associated antigen that is aberrantly expressed in cancer and inflammatory bowel disease (IBD). Even though immune cells express low MUC1 levels, their modulations of MUC1 are important in tumor progression. Consistent with p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c80fe7b8adf81e42bd23eb3712d819b
https://doi.org/10.1158/1078-0432.c.6522167
https://doi.org/10.1158/1078-0432.c.6522167
Autor:
Sandra J. Gendler, Peter A. Cohen, Jonathan A. Leighton, Ronald J. Marler, Jessica E. Gorman, Cathy S. Madsen, Tze Wei Poh
Supplementary Figures 1 and 2 - PDF file 144K, Supplementary Figure 1: DNA from PBMCs of all engrafted female chimeric mice showed presence of Y chromosome gene. DNA from PBMCs of WT-->WT and KO-->WT mice showed presence of only Muc1 or LacZ gene res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec8f38acb94bf071c9aa4b44bde24d6
https://doi.org/10.1158/1078-0432.22451318
https://doi.org/10.1158/1078-0432.22451318
Autor:
Christine L. Hattrup, Judy M. Bradley, Kari L. Kotlarczyk, Cathy S. Madsen, Ronald J. Marler, Sandra J. Gendler
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 1, Pp 57-63 (2008)
Background: Though the importance of the transmembrane mucin MUC1 in mammary oncogenesis has long been recognized, the relative contributions of the cytoplasmic tail and tandem repeat domains are poorly understood.Methods: To address this, mouse mode
Externí odkaz:
https://doaj.org/article/5bef0c5ac913454e949bff9c449db626
Autor:
null Douglas O. Faigel, null Vijay P. Singh, null Krutika Patel, null Alaa El Chami, null Catherine C. Raymond, null Tracy L. Landreth, null Ronald J. Marler, null Douglas F. Lake, null Toufic Kachaamy
Publikováno v:
Journal of Cancer Research Updates. 7:102-108
Background and Aims: Patients with diffuse liver metastases have systemic chemotherapy as their only treatment option. We developed Endoscopic Ultrasound (EUS)-guided portal injection chemotherapy (EPIC) to increase drug levels in hepatic tissue as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d44e4f076af34fee0408072a32a9c278
https://doi.org/10.30683/1929-2279.2018.07.04.1
https://doi.org/10.30683/1929-2279.2018.07.04.1
Publikováno v:
Gastrointestinal Endoscopy. 83:444-446
Direct injection of chemotherapy into the portal vein for treatment of liver metastases may increase hepatic tissue levels while decreasing systemic levels and toxicities. We aimed to evaluate EUS-guided portal injection chemotherapy (EPIC) by using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46169a83d1e17d09936e6946f3e092ca
https://doi.org/10.1016/j.gie.2015.08.064
https://doi.org/10.1016/j.gie.2015.08.064
Autor:
Anisha Singh, Ianko D. Iankov, Bruce Amiot, Shennen A. Mao, Scott L. Nyberg, Richard L. Ehman, Joseph B. Lillegard, Raymond D. Hickey, Meng Yin, Faysal Elgilani, Markus Grompe, Jaime Glorioso, Ronald J. Marler, Piero Rinaldo
Hereditary tyrosinemia type 1 (HT1) is an autosomal recessive disease caused by deficiency in fumarylacetoacetate hydrolase, the last enzyme in the tyrosine catabolic pathway. In this study, we investigated whether fumarylacetoacetate hydrolase defic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d7b8c6f09609342cae34a98e992622
https://europepmc.org/articles/PMC5225308/
https://europepmc.org/articles/PMC5225308/
Autor:
Jaime Glorioso, Cary O. Harding, Piero Rinaldo, Markus Grompe, Bruce Amiot, Ronald J. Marler, Raymond D. Hickey, Joseph B. Lillegard, James E. Fisher, Scott L. Nyberg, Milton J. Finegold, Shennen A. Mao
Publikováno v:
Stem Cell Research, Vol 13, Iss 1, Pp 144-153 (2014)
Hereditary tyrosinemia type I (HT1) is caused by deficiency in fumarylacetoacetate hydrolase (FAH), an enzyme that catalyzes the last step of tyrosine metabolism. The most severe form of the disease presents acutely during infancy, and is characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca9c42edad60bbfe7f1e56dff0ebc9b
https://doi.org/10.1016/j.scr.2014.05.003
https://doi.org/10.1016/j.scr.2014.05.003
Autor:
Luciana L. Almada, Fergus J. Couch, Lizhi Zhang, Lisa D. Mills, Ronald J. Marler, Martin E. Fernandez-Zapico, Marina Pasca di Magliano, Yaqing Zhang, Marta Herreros-Villanueva, Cynthia Wetmore
Publikováno v:
Journal of Biological Chemistry. 288:11786-11794
Although the biological role of KRAS is clearly established in carcinogenesis, the molecular mechanisms underlying this phenomenon are not completely understood. In this study, we provide evidence of a novel signaling network regulated by the transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8cb3679fc4da80706c7823095c00b8
https://doi.org/10.1074/jbc.m112.438846
https://doi.org/10.1074/jbc.m112.438846
Autor:
Matthew P. Goetz, Anne Gingery, Kevin S. Pitel, Urszula T. Iwaniec, Renee M. McGovern, Joel M. Reid, Russell T. Turner, James N. Ingle, Ronald J. Marler, John R. Hawse, Malayannan Subramaniam
Publikováno v:
Endocrinology. 158(10)
Endoxifen, the primary active metabolite of tamoxifen, is currently being investigated as a novel endocrine therapy for the treatment of breast cancer. Tamoxifen is a selective estrogen receptor modulator that elicits potent anti-breast cancer effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec3cfa7e503d4c730424ea49da8d7e55
https://pubmed.ncbi.nlm.nih.gov/28977607
https://pubmed.ncbi.nlm.nih.gov/28977607