Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ronald J. Lorentzen"'
Publikováno v:
Environmental and Molecular Mutagenesis. 59:100-102
Autor:
Paul C. Howard, Raghubir P. Sharma, Thomas J. Bucci, Kenneth A. Voss, Ronald T. Riley, Ronald J. Lorentzen
Publikováno v:
Cancer Detection and Prevention. 26:1-9
Fumonisins are fungal metabolites and suspected human carcinogens. They inhibit ceramide synthase in vitro, enhance tumor necrosis factor alpha (TNFalpha) production, and cause apoptosis. Fumonisin B1 (FB1) was fed to rats and mice for 2 years or, in
Autor:
Alan Warbritton, Ronald J. Lorentzen, Paul C. Howard, J D Thurman, K A Voss, Thomas J. Bucci, Robert M. Kovach
Publikováno v:
Environmental Health Perspectives
Fumonisin B1(FB1) is a fungal metabolite of Fusarium verticillioides (= F. moniliforme), a fungus that grows on many crops worldwide. Previous studies demonstrated that male BD IX rats consuming diets containing 50 ppm fumonisin B1 developed hepatoce
Autor:
Alan Warbritton, Michael E Stack, Paul C. Howard, Kenneth A. Voss, Robert M. Kovach, Robert M Eppley, Thomas J. Bucci, Ronald J. Lorentzen
Publikováno v:
Environmental Health Perspectives
Fumonisin B1 (FB1) is a mycotoxin isolated from Fusarium fungi that contaminate crops worldwide. A previous study demonstrated that FB1 promoted preneoplastic foci in initiated rats and induced hepatocellular carcinomas in BD IX rats at 50 parts per
Autor:
Michael E. Stack, Kenneth A. Voss, Paul C. Howard, Ronald J. Lorentzen, Thomas J. Bucci, Robert M. Kovach, Robert M. Eppley, Alan Warbritton
Publikováno v:
Mycotoxins. 1999:45-54
Autor:
K.L. Hulebak, Ronald P. Brown, J.A. Cavagnaro, Margaret A. Miller, J.A. Axelrad, Ronald J. Lorentzen, Bernard A. Schwetz, David W. Gaylor, W.H. Cyr, L.T. Mulligan
Publikováno v:
Regulatory Toxicology and Pharmacology. 26:307-321
The U.S. Food and Drug Administration (FDA) regulates a wide variety of consumer products. Safety issues involve chemical and microbial contaminants in food, biologics, and medical devices; side effects from prescription and nonprescription drugs; re
Publikováno v:
Journal of the American Chemical Society. 114:2181-2187
Enantioenriched 1-substituted indans were prepared from (R)- 1-indancarboxylic acid and (R)-1-indanylacetic acid as model compounds for the correlation of their absolute configurations with the sign of the 1 L b Cotton effects (CEs) from about 250 to
Publikováno v:
Risk Analysis. 10:429-435
Methylene chloride has been shown to be a lung and liver carcinogen in the mouse; yet, the current epidemiologic data show no adverse health effects associated with chronic exposure to this compound. Hearne et al.(1) have compared the results of a la
Autor:
Ronald J. Lorentzen
Publikováno v:
Toxicologic Pathology. 38:506-507
The major provocative conjecture of Dr. Cohen’s article is contained in the subtitle: ‘‘The Two-Year Bioassay Is No Longer Necessary.’’ I truly wish that I could board this train; I cannot. Neither, however, do I wish to lay on the tracks t
Autor:
Daniel R. Doerge, Ronald J. Lorentzen, Lionel A. Poirier, Margaret A. Miller, David W. Gaylor, Fred F. Kadlubar, Bernard A. Schwetz, Daniel A. Casciano
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 30(3)
Recently, changes have been proposed in the criteria historically used in the evaluation of the applicability to humans of some of the results obtained from the rodent carcinogenicity bioassay data. These questions center on the suitability of the ro