Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ronald J Jackson"'
Autor:
Danushka K Wijesundara, Charani Ranasinghe, Ronald J Jackson, Brett A Lidbury, Christopher R Parish, Benjamin J C Quah
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e105366 (2014)
Qualitative characteristics of cytotoxic CD8+ T cells (CTLs) are important in measuring the effectiveness of CTLs in controlling HIV-1 infections. Indeed, in recent studies patients who are naturally resistant to HIV-1 infections have been shown to p
Externí odkaz:
https://doaj.org/article/0e731bca0c8e4a89a7b6be79b78c4e03
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e55788 (2013)
With the hope of understanding how interleukin (IL)-4 and IL-13 modulated quality of anti-viral CD8(+) T cells, we evaluated the expression of receptors for these cytokines following a range of viral infections (e.g. pox viruses and influenza virus).
Externí odkaz:
https://doaj.org/article/80c343fe4a3a4345bf62ebef52d3271a
Autor:
Danushka K. Wijesundara, Ronald J. Jackson, Eric J. Gowans, Charani Ranasinghe, S. Mahboob, M.I. Jaeson, Zheyi Li, Branka Grubor-Bauk, Sreeja Roy
Publikováno v:
Vaccine. 37:1266-1276
This study demonstrates that route and viral vector can significantly influence the innate lymphoid cells (ILC) and dendritic cells (DC) recruited to the vaccination site, 24 h post delivery. Intranasal (i.n.) vaccination induced ST2/IL-33R+ ILC2, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed9cf8e52167fcc6751244fdccc34eb
https://doi.org/10.1016/j.vaccine.2019.01.045
https://doi.org/10.1016/j.vaccine.2019.01.045
Publikováno v:
European Journal of Immunology. 48:1153-1163
In this study, recombinant pox viral vaccination was shown to induce highly elevated IgG2a and low IgG1 antibody expression in mice lacking IL-4 or STAT6, whilst IL-13-/- mice exhibited elevated IgG1, but very low IgG2a. These findings revealed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423215b89bd7772a293af645a490b666
https://doi.org/10.1002/eji.201747463
https://doi.org/10.1002/eji.201747463
Publikováno v:
Journal of General Virology. 98:2556-2568
To establish the importance of virus–heparan sulfate (HS) interactions in virus infectivity, the poxvirus vaccinia virus (VACV) was used, as it binds HS and has both enveloped virus (EV) and non-enveloped mature virus (MV) forms. Initial studies sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba269b105e124a047ecf4251d82b200
https://doi.org/10.1099/jgv.0.000921
https://doi.org/10.1099/jgv.0.000921
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 3, Iss 1, Pp 1-9 (2018)
npj Vaccines, Vol 3, Iss 1, Pp 1-9 (2018)
This study demonstrates that the fate of a vaccine is influenced by the cytokines produced by the innate lymphoid cells (ILC) recruited to the vaccination site, and it is vaccine route and adjuvant dependent. Intranasal virus vaccination induced ST2/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::637ecdf8eff05597445bbc65e19ba35c
https://pubmed.ncbi.nlm.nih.gov/29560282
https://pubmed.ncbi.nlm.nih.gov/29560282
Publikováno v:
The Journal of General Virology
We have previously established that mucosal uptake of recombinant fowlpox virus (rFPV) vaccines is far superior to other vector-based vaccines. Specifically, intranasal priming with rFPV vaccines can recruit unique antigen-presenting cells, which ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcb915f89315af9dccf49ba839193c44
https://pubmed.ncbi.nlm.nih.gov/28056224
https://pubmed.ncbi.nlm.nih.gov/28056224
Publikováno v:
Encyclopedia of Signaling Molecules ISBN: 9781461464389
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ca6068c3c89f9f4e6c1b113c20a2484
https://doi.org/10.1007/978-1-4614-6438-9_101978-1
https://doi.org/10.1007/978-1-4614-6438-9_101978-1
Publikováno v:
Mucosal Immunology. 6:1068-1080
We have established that mucosal immunization can generate high-avidity human immunodeficiency virus (HIV)-specific CD8(+) T cells compared with systemic immunization, and interleukin (IL)-13 is detrimental to the functional avidity of these T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80aea73c3182565a80256905e6bd2e21
https://doi.org/10.1038/mi.2013.1
https://doi.org/10.1038/mi.2013.1