Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Ronald J Hill"'
Publikováno v:
PLoS Genetics, Vol 11, Iss 7, p e1005394 (2015)
Juvenile hormones (JHs) play a major role in controlling development and reproduction in insects and other arthropods. Synthetic JH-mimicking compounds such as methoprene are employed as potent insecticides against significant agricultural, household
Externí odkaz:
https://doaj.org/article/c1227043c52043e69f3cf56282d14557
Autor:
Ronald J. Hill
First Published in 1992. The present collection of essays brings together the concepts of change and development, by using the concept of evolution to explore various forms of change in the communist and'post-communist'world. The author's experience
Autor:
J. Michael Bradshaw, Jens Oliver Funk, David M. Goldstein, Mary E. Gerritsen, Ronald J. Hill, Dane E. Karr, Kwan Leung, Jacob LaStant, Danny Tam, Yan Xing, Timothy D. Owens, Erik Verner, Vernon T. Phan, Ken A. Brameld, Eleni Venetsanakos
Supplementary Table S1. Percentage of enzyme activity following dialysis compared to a non-compound treated control; Supplementary Figure S1. PRN1371 inhibited SNU16 cell proliferation as assessed by BrdU incorporation; Supplementary Figure S2. PRN13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c5e9e9ff8205d0aa30e44bc8c20f2ed
https://doi.org/10.1158/1535-7163.22503429.v1
https://doi.org/10.1158/1535-7163.22503429.v1
Autor:
Timothy D. Owens, Ken A. Brameld, Erik J. Verner, Tony Ton, Xiaoyan Li, Jiang Zhu, Mohammad R. Masjedizadeh, J. Michael Bradshaw, Ronald J. Hill, Danny Tam, Angelina Bisconte, Eun Ok Kim, Michelle Francesco, Yan Xing, Jin Shu, Dane Karr, Jacob LaStant, David Finkle, Natalie Loewenstein, Helena Haberstock-Debic, Michael J. Taylor, Philip Nunn, Claire L. Langrish, David M. Goldstein
Publikováno v:
Journal of medicinal chemistry. 65(7)
Bruton's tyrosine kinase (BTK), a Tec family tyrosine kinase, is critical in immune pathways as an essential intracellular signaling element, participating in both adaptive and immune responses. Currently approved BTK inhibitors are irreversible cova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288f1908751aebe6ff2c56fdf8695ab7
https://pubmed.ncbi.nlm.nih.gov/35302767
https://pubmed.ncbi.nlm.nih.gov/35302767
Autor:
Ann Mongan, Ronald J. Hill, Melissa Hopper, Taisei Kinoshita, Tarikere Gururaja, James P. Dean
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 372:331-338
Kinases form an attractive class of targets for small molecule inhibitors, but similarity among their adenosine triphosphate binding sites presents difficulties for developing selective drugs. Standard methods of evaluating selectivity of most revers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0ad5aeec9339d4e8d05cabd4f4c463
https://doi.org/10.1124/jpet.119.262063
https://doi.org/10.1124/jpet.119.262063
Autor:
Thomas Nebl, Joel P. Mackay, Jason Low, William J. McKinstry, Jan Shaw, Bin Ren, George O. Lovrecz, Lenka Bittova, Lindsay G. Sparrow, Ronald J. Hill, Marek Jindra, Louis Lu, Tram Phan
Publikováno v:
The Journal of Biological Chemistry
Juvenile hormone (JH) plays vital roles in insect reproduction, development, and in many aspects of physiology. JH primarily acts at the gene-regulatory level through interaction with an intracellular receptor (JHR), a ligand-activated complex of tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505faf7d5cd39986321b4414f709b2d0
https://pubmed.ncbi.nlm.nih.gov/34758356
https://pubmed.ncbi.nlm.nih.gov/34758356
Autor:
J. Michael Bradshaw, Angelina Bisconte, Ken A. Brameld, Claire L. Langrish, Timothy D. Owens, David Michael Goldstein, Catherine A. Outerbridge, Philip A. Nunn, Ronald J. Hill, Jacob LaStant, Stephen D. White, Jin Shu, Michelle Francesco, Yan Xing
Publikováno v:
J Immunol
Journal of immunology (Baltimore, Md. : 1950), vol 206, iss 7
Journal of immunology (Baltimore, Md. : 1950), vol 206, iss 7
Bruton tyrosine kinase (BTK) is expressed in B cells and innate immune cells, acting as an essential signaling element in multiple immune cell pathways. Selective BTK inhibition has the potential to target multiple immune-mediated disease pathways. R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e34ff3a7e358b3f78ad8297b0f039949
https://europepmc.org/articles/PMC7980532/
https://europepmc.org/articles/PMC7980532/
Autor:
Petra Bizikova, Steven G. Gourlay, Catherine A. Outerbridge, Philip A. Nunn, Ronald J. Hill, Dori L. Borjesson, Stephen D. White, Tyler J.M. Jordan, Michelle Francesco, Angelina Bisconte, Carolyn B. Emery, Dedee F. Murrell, Elizabeth C. Goodale, Mohammad Masjedizadeh
Publikováno v:
Veterinary dermatologyReferences. 31(5)
Bruton's tyrosine kinase (BTK) is important in B-cell signalling. Efficacy has been reported for BTK inhibitors (BTKi) in human autoimmune diseases. Canine pemphigus foliaceus (cPF) is one of the most common canine autoimmune skin diseases.To determi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd90e1977767a4dee881b0a6ecf596e4
https://pubmed.ncbi.nlm.nih.gov/32803903
https://pubmed.ncbi.nlm.nih.gov/32803903
Autor:
Andreas Margraf, Ronald J. Hill, Angelina Bisconte, Claire L Langrish, Benedito Eduardo Correia, J. Michael Bradshaw, Clifford A. Lowell, Alexander Zarbock, Stephanie Volmering, Jan M. Herter
Publikováno v:
British Journal of Pharmacology. 175:429-439
Background and purpose Following inflammatory stimuli, neutrophils are recruited to sites of inflammation and exert effector functions that often have deleterious effects on tissue integrity, which can lead to organ failure. Bruton's tyrosine kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7aec17ff4007090a3c06bf9508c4309
https://doi.org/10.1111/bph.14090
https://doi.org/10.1111/bph.14090
Autor:
Andrew E. Pomerantz, Wael Abdallah, Justin E. Birdwell, Michael B. Grayson, Ronald J. Hill, Sudipa Mitra-Kirtley, Kyle D. Bake, Trudy B. Bolin, Paul R. Craddock, Michael D. Lewan
Publikováno v:
Energy & Fuels. 30:6264-6270
The sulfur speciation of source rock bitumen (chloroform-extractable organic matter in sedimentary rocks) was examined using sulfur K-edge X-ray absorption near-edge structure (XANES) spectroscopy for a suite of 11 source rocks from around the world.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db41ec563322655d9faa9a6cbf463419
https://doi.org/10.1021/acs.energyfuels.6b00744
https://doi.org/10.1021/acs.energyfuels.6b00744