Zobrazeno 1 - 10
of 347
pro vyhledávání: '"Ronald J Falk"'
Autor:
Christian Agosto‐Burgos, Eveline Y Wu, Marie A Iannone, Yichun Hu, Susan L Hogan, Candace D Henderson, Kristin B Kennedy, Lauren Blazek, Carolina A Herrera, Dominique Munson, Ronald J Falk, Dominic J Ciavatta, Meghan E Free
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 11, Pp n/a-n/a (2022)
Abstract Objectives T regulatory cells (Tregs) are a heterogeneous group of immunoregulatory cells that dampen self‐harming immune responses and prevent the development of autoimmune diseases. In anti‐neutrophil cytoplasmic autoantibody (ANCA) va
Externí odkaz:
https://doaj.org/article/680b925a8fee483e85a7f6dab3ad0451
Autor:
Olivier M Lardinois, Leesa J Deterding, Jacob J Hess, Caroline J Poulton, Candace D Henderson, J Charles Jennette, Patrick H Nachman, Ronald J Falk
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0213215 (2019)
BACKGROUND:Anti-neutrophil cytoplasmic autoantibodies (ANCA) directed against myeloperoxidase (MPO) and proteinase 3 (PR3) are pathogenic in ANCA-associated vasculitis (AAV). The respective role of IgG Fc and Fab glycosylation in mediating ANCA patho
Externí odkaz:
https://doaj.org/article/40ab3e38a1bd4384a8860d2011b3e750
Autor:
Meghan A Jobson, Susan L Hogan, Colin S Maxwell, Yichun Hu, Gerald A Hladik, Ronald J Falk, Michael C Beuhler, William F Pendergraft
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143044 (2015)
BackgroundEthylene glycol is highly toxic and represents an important cause of poisonings worldwide. Toxicity can result in central nervous system dysfunction, cardiovascular compromise, elevated anion gap metabolic acidosis and acute kidney injury.
Externí odkaz:
https://doaj.org/article/629f063d8e044daa83c857e6342a4b8e
Autor:
Monica L. Reynolds, Keisha L. Gibson, Tracy A. Manuck, Caroline J. Poulton, Lauren Blazek, Alison M. Stuebe, Susan L. Hogan, Ronald J. Falk, Vimal K. Derebail
Publikováno v:
Frontiers in Nephrology, Vol 4 (2024)
Individuals with lupus nephritis (LN) are at high risk of adverse maternal and fetal outcomes in pregnancy. Outside of pregnancy, proliferative lesions on kidney biopsies are associated with disease progression, but these have not been consistently a
Externí odkaz:
https://doaj.org/article/10e2b738d06d4fe09c07b4308a755527
Autor:
Mary M. Collie, Dhruti P. Chen, Yichun Hu, Lauren N. Blazek, Vimal K. Derebail, Eveline Y. Wu, Koyal Jain, Nicole Orzechowski, Caroline J. Poulton, Candace D. Henderson, Ronald J. Falk, Susan L. Hogan
Publikováno v:
Frontiers in Nephrology, Vol 4 (2024)
The role of stressors, insect bites, and infections on disease relapse of ANCA vasculitis has yet to be entirely explored, with limited retrospective studies focused on disease onset from small participant cohorts. Our study analyzes longitudinal sur
Externí odkaz:
https://doaj.org/article/0e7c11966c614e8b87c448b79ca0bf9d
Autor:
Manish K. Saha, Susan L. Hogan, Ronald J. Falk, Edward L. Barnes, Yichun Hu, Abhijit V. Kshirsagar, Carolyn T. Thorpe
Publikováno v:
Kidney Medicine, Vol 6, Iss 7, Pp 100836- (2024)
Rationale & Objective: About 25%-40% of patients with inflammatory bowel disease (IBD) may have extraintestinal manifestations, mainly involving the liver, skin, and joints. Kidney involvement in patients with IBD has been reported, but there are no
Externí odkaz:
https://doaj.org/article/a9695771a9c3435a94f4379fbf019110
Autor:
Yali Cao, Jiajin Yang, Kerry Colby, Susan L Hogan, Yichun Hu, Caroline E Jennette, Elisabeth A Berg, Youkang Zhang, J Charles Jennette, Ronald J Falk, Gloria A Preston
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42783 (2012)
Consequences of expression of the protein tyrosine phosphatase nonreceptor 22 (PTPN22) gain-of-function variant were evaluated in leukocytes from patients with anti-neutrophil cytoplasmic autoantibody (ANCA) disease. The frequency of the gain-of-func
Externí odkaz:
https://doaj.org/article/1a0fc542ba7d4ca8aebf9b9de5b08c20
Autor:
Dhruti P. Chen, Claudia P. Aiello, DeMoris McCoy, Taylor Stamey, Jiajin Yang, Susan L. Hogan, Yichun Hu, Vimal K. Derebail, Eveline Y. Wu, J. Charles Jennette, Ronald J. Falk, Dominic J. Ciavatta
Publikováno v:
JCI Insight, Vol 8, Iss 4 (2023)
A GWAS of patients with anti-neutrophil cytoplasmic antibodies (ANCAs) found an association between proteinase-3 ANCA (PR3-ANCA) and a single nucleotide polymorphism (rs62132293) upstream of PRTN3, encoding PR3. The variant (G allele) was shown to be
Externí odkaz:
https://doaj.org/article/6edfe8f22c0c4cc28e5dfa690c9af7ec
Autor:
Carmen E. Mendoza, Elizabeth J. Brant, Matthew L. McDermott, Anne Froment, Yichun Hu, Susan L. Hogan, J. Charles Jennette, Ronald J. Falk, Patrick H. Nachman, Vimal K. Derebail, Donna O’Dell Bunch
Publikováno v:
Kidney International Reports, Vol 4, Iss 11, Pp 1617-1629 (2019)
Introduction: Venous thromboembolism (VTE) is a life-threatening complication of anti-neutrophil cytoplasmic autoantibody (ANCA) vasculitis whose mechanism remains incompletely elucidated. We tested the hypothesis that elevated microparticle tissue f
Externí odkaz:
https://doaj.org/article/88b0093555af424b88da88115c76c023
Autor:
Ogo Egbuna, Brandon Zimmerman, George Manos, Anne Fortier, Madalina C. Chirieac, Leslie A. Dakin, David J. Friedman, Kate Bramham, Kirk Campbell, Bertrand Knebelmann, Laura Barisoni, Ronald J. Falk, Debbie S. Gipson, Michael S. Lipkowitz, Akinlolu Ojo, Mark E. Bunnage, Martin R. Pollak, David Altshuler, Glenn M. Chertow
Publikováno v:
New England Journal of Medicine. 388:969-979
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::647a308969978ba8f826907be1073246
https://doi.org/10.1056/nejmoa2202396
https://doi.org/10.1056/nejmoa2202396