Zobrazeno 1 - 10
of 225
pro vyhledávání: '"Ronald Herbst"'
Autor:
Ronald Herbst, Anthony Rodriguez, Kei Yasuda, Philipp Steiner, Liyang Diao, Jianwen Feng, Matthew Iovino, Sara Lewandowski, Dan Felitsky, Ben Keller, Ona Miller, Alyssa Quigley, Jan Pinkas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/d58746e935aa484e91284e907bc0b59c
Autor:
Saba Nayar, Elena Pontarini, Joana Campos, Onorina Berardicurti, Charlotte G. Smith, Saba Asam, David H. Gardner, Serena Colafrancesco, Davide Lucchesi, Rachel Coleby, Ming-May Chung, Valentina Iannizzotto, Kelly Hunter, Simon J. Bowman, Gianluca Carlesso, Ronald Herbst, Helen M. McGettrick, Jeff Browning, Christopher D. Buckley, Benjamin A. Fisher, Michele Bombardieri, Francesca Barone
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
The study suggests a link between ICOS-ICOSL signaling and LTa3 induction on T cells. LTa3 subsequently activates fibroblasts in the salivary gland, leading to formation of tertiary lymphoid tissues (TLS).
Externí odkaz:
https://doaj.org/article/d98526377cb948829a419d58788242d6
Autor:
Diane Damotte, Sarah Warren, Jennifer Arrondeau, Pascaline Boudou-Rouquette, Audrey Mansuet-Lupo, Jérôme Biton, Hanane Ouakrim, Marco Alifano, Claire Gervais, Audrey Bellesoeur, Nora Kramkimel, Camille Tlemsani, Barbara Burroni, Angéline Duche, Franck Letourneur, Han Si, Rebecca Halpin, Todd Creasy, Ronald Herbst, Xing Ren, Pascale Morel, Alessandra Cesano, François Goldwasser, Karen Leroy
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background The 18-gene tumor inflammation signature (TIS) is a clinical research assay that enriches for clinical benefit to immune checkpoint blockade. We evaluated its ability to predict clinical benefit of immunotherapy in cancer patients
Externí odkaz:
https://doaj.org/article/b75c5fd83d2d4639a48bed140c36dd2f
Autor:
Stefanie R. Mullins, John P. Vasilakos, Katharina Deschler, Iwen Grigsby, Pete Gillis, Julius John, Matthew J. Elder, John Swales, Elina Timosenko, Zachary Cooper, Simon J. Dovedi, Andrew J. Leishman, Nadia Luheshi, James Elvecrog, Ashenafi Tilahun, Richard Goodwin, Ronald Herbst, Mark A. Tomai, Robert W. Wilkinson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract Background Immune checkpoint blockade (ICB) promotes adaptive immunity and tumor regression in some cancer patients. However, in patients with immunologically “cold” tumors, tumor-resident innate immune cell activation may be required to
Externí odkaz:
https://doaj.org/article/664a845e229648008b22d687ebf6b261
Autor:
Reena Varkey, Qun Du, Jodi L Karnell, Xiaodong Xiao, Kerry A Casey, Rob Woods, Kim Rosenthal, Susan Wilson, William F Dall'Acqua, Herren Wu, Ronald Herbst, Rachel Ettinger, Melissa Damschroder
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211236 (2019)
Interleukin-21 (IL-21), a member of the common cytokine receptor γ chain (γc) family, is secreted by CD4+ T cells and natural killer T cells and induces effector function through interactions with the IL-21 receptor (IL-21R)/γc complex expressed o
Externí odkaz:
https://doaj.org/article/e7e6a5a71ae44ef09369d6a607a0b924
Autor:
Emma E. Dutton, Ana Camelo, Matthew Sleeman, Ronald Herbst, Gianluca Carlesso, Gabrielle T. Belz, David R. Withers
Publikováno v:
Wellcome Open Research, Vol 2 (2018)
Background: Innate lymphoid cells (ILCs) have now been identified within most tissues of the body and current evidence indicates that this family of cells play a fundamental role in maintaining tissue homeostasis. However, few studies have compared t
Externí odkaz:
https://doaj.org/article/587b3d437ad64bb0955ea7d86fb57f48
Autor:
Liyan Jiang, Jiaqi Huang, Brandon W Higgs, Zhibin Hu, Zhan Xiao, Xin Yao, Sarah Conley, Haihong Zhong, Zheng Liu, Philip Brohawn, Dong Shen, Song Wu, Xiaoxiao Ge, Yue Jiang, Yizhuo Zhao, Yuqing Lou, Chris Morehouse, Wei Zhu, Yinong Sebastian, Meggan Czapiga, Vaheh Oganesyan, Haihua Fu, Yanjie Niu, Wei Zhang, Katie Streicher, David Tice, Heng Zhao, Meng Zhu, Lin Xu, Ronald Herbst, Xinying Su, Yi Gu, Shyoung Li, Lihua Huang, Jianren Gu, Baohui Han, Bahija Jallal, Hongbing Shen, Yihong Yao
Publikováno v:
PLoS Genetics, Vol 12, Iss 4, p e1005895 (2016)
Small cell lung cancer (SCLC) is an aggressive disease with poor survival. A few sequencing studies performed on limited number of samples have revealed potential disease-driving genes in SCLC, however, much still remains unknown, particularly in the
Externí odkaz:
https://doaj.org/article/5a94d0c0e61d478c84e2d5a2d8db5b34
Autor:
Bo Chen, Allison L Miller, Marlon Rebelatto, Yambasu Brewah, Daniel C Rowe, Lori Clarke, Meggan Czapiga, Kim Rosenthal, Tomozumi Imamichi, Yan Chen, Chew-Shun Chang, Partha S Chowdhury, Brian Naiman, Yue Wang, De Yang, Alison A Humbles, Ronald Herbst, Gary P Sims
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0115828 (2015)
Release of endogenous damage associated molecular patterns (DAMPs), including members of the S100 family, are associated with infection, cellular stress, tissue damage and cancer. The extracellular functions of this family of calcium binding proteins
Externí odkaz:
https://doaj.org/article/60f3d5336bb947d188644086d880d193
Autor:
Isharat Yusuf, Jessica Stern, Tom M McCaughtry, Sandra Gallagher, Hong Sun, Changshou Gao, Thomas Tedder, Gianluca Carlesso, Laura Carter, Ronald Herbst, Yue Wang
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e102791 (2014)
BACKGROUND: Continuous support from follicular CD4(+) T helper (Tfh) cells drives germinal center (GC) responses, which last for several weeks to produce high affinity memory B cells and plasma cells. In autoimmune Sle1 and NZB/W F1 mice, elevated nu
Externí odkaz:
https://doaj.org/article/14521c2dfb3045498d255b23c599e9dd
Publikováno v:
Journal of Clinical Medicine, Vol 5, Iss 12, p 107 (2016)
Exaggerated or inappropriate responses by B cells are an important feature in many types of autoimmune neurological diseases. The recent success of B-cell depletion in the treatment of multiple sclerosis (MS) has stimulated the development of novel B
Externí odkaz:
https://doaj.org/article/54d62db2d8974570883975f59954a868