Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Ronald H. L. Li"'
Autor:
Laetitia Duler, Lance Visser, Nghi Nguyen, Lynelle R. Johnson, Joshua A. Stern, Ronald H. L. Li
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 4, Pp 2052-2063 (2024)
Abstract Background Pulmonary hypertension (PH) in dogs with myxomatous mitral valve disease (MMVD) is caused by increased pulmonary venous pressure. Thrombosis, vascular remodeling, and vasoconstriction mediated by platelets could exacerbate PH. Hyp
Externí odkaz:
https://doaj.org/article/82fe28a9c9594256b23d55f93f6dc368
Autor:
Victor N. Rivas, Avalene W. K. Tan, Meg Shaverdian, Nghi P. Nguyen, Jalena R. Wouters, Joshua A. Stern, Ronald H. L. Li
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 38, Iss 3, Pp 1408-1417 (2024)
Abstract Background Glanzmann's thrombasthenia (GT) is a congenital platelet disorder affecting approximately 1:1 000 000 people globally and characterized by impaired platelet aggregation and clot retraction. Autosomal recessive, loss‐of‐functio
Externí odkaz:
https://doaj.org/article/3abd2cd84e3c46a8ac88a18c35c57223
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionCats with cardiomyopathy face an increased risk of arterial thromboembolism (ATE). Although clopidogrel is frequently utilized to mitigate this risk, feline responses to this therapy exhibit variability. This study evaluated 2 viscoelasti
Externí odkaz:
https://doaj.org/article/99bc7641c21748f28b225f236091da44
Autor:
Danika L. Bannasch, Danielle T. Oertle, Julia Vo, Kevin L. Batcher, Joshua A. Stern, Joanna L. Kaplan, Ronald H. L. Li, Indiana E. Madden, Matthias Christen, Tosso Leeb, Nikhil Joshi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Dilated cardiomyopathy (DCM) is characterized by decreased systolic function and dilation of one or both ventricles, often leading to heart failure or sudden death. Two 10-month-old sibling Nova Scotia Duck Tolling Retrievers (NSDTR) died ac
Externí odkaz:
https://doaj.org/article/ef7067c58fce4a5db32de339fd96ab57
Autor:
Sara T. Lo, Ronald H. L. Li, Catherine J. Georges, Nghi Nguyen, Cheyenne K. Chen, Claire Stuhlmann, Maureen Sigmund Oldach, Victor Noel Rivas, Samantha Fousse, Samantha P. Harris, Joshua A. Stern
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 4, Pp 1390-1400 (2023)
Abstract Background Dual antithrombotic treatment (DAT) with clopidogrel and rivaroxaban sometimes is prescribed to cats with hypertrophic cardiomyopathy at risk of thromboembolism. To date, no studies have evaluated their combined effects on platele
Externí odkaz:
https://doaj.org/article/37da3c77fb914dde8637aebb05fb0b69
Autor:
Ashley L. Walker, Ronald H. L. Li, Nghi Nguyen, Carina E. Jauregui, Kathryn M. Meurs, Allison L. Gagnon, Joshua A. Stern
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Autoantibodies to desmoglein-2 have been associated with arrhythmogenic right ventricular cardiomyopathy (ARVC) in people. ARVC is a common disease in the Boxer dog. The role of anti-desmoglein-2 antibodies in Boxers with ARVC and correlatio
Externí odkaz:
https://doaj.org/article/c8c78cf5a36f489fa4212993ac4de86f
Autor:
Ronald H. L. Li, Arianne Fabella, Nghi Nguyen, Joanna L. Kaplan, Eric Ontiveros, Joshua A. Stern
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 37, Iss 2, Pp 490-502 (2023)
Abstract Background Cats with hypertrophic cardiomyopathy (HCM) are at risk of cardiogenic arterial thromboembolism (CATE). Neutrophil extracellular traps (NETs) may be a potential biomarker and therapeutic target for cardiomyopathy in cats. Hypothes
Externí odkaz:
https://doaj.org/article/6699135952e842e4a9abaa77200557df
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
IntroductionThe antiplatelet effect of clopidogrel can vary between patients. A modified thromboelastography (TEG) protocol (TEG-Platelet Mapping assay® [TEG-PM]) can be used for clopidogrel monitoring but is not widely available. Thrombin generatio
Externí odkaz:
https://doaj.org/article/8563defd20dd45d28dbdba44f53ff770
Publikováno v:
Frontiers in Veterinary Science, Vol 10 (2023)
Disseminated intravascular coagulation following melarsomine therapy for Dirofilaria immitis (D. immitis) is reported in a 9-year-old female intact pit bull-type dog. The dog had been diagnosed with D. immitis (antigen and microfilaria positive) and
Externí odkaz:
https://doaj.org/article/e3ef0e6ab49e415ca3b2ec0937837919
Autor:
Yu Ueda, Ronald H. L. Li, Nghi Nguyen, Eric S. Ontiveros, Samantha L. Kovacs, Maureen S. Oldach, Karen M. Vernau, Michael H. Court, Joshua A. Stern
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Clopidogrel is converted to its active metabolite by cytochrome P450 isoenzymes and irreversibly inhibits platelet activation by antagonizing the adenosine-diphosphate (ADP) receptor. It is frequently used in cats with hypertrophic cardiomyo
Externí odkaz:
https://doaj.org/article/ddb2a51e34504216b33792c1c628f25d