Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ronald G. Jubin"'
Publikováno v:
BioTechniques, Vol 46, Iss 6, Pp 474-475 (2009)
Externí odkaz:
https://doaj.org/article/00ece511f72b4ee78f9bdcb32f91c9b0
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32542 (2012)
Low doses of anticancer drugs have been shown to enhance antitumor immune response and increase the efficacy of immunotherapy. The molecular basis for such effects remains elusive, although selective depletion of T regulatory cells has been demonstra
Externí odkaz:
https://doaj.org/article/4d3adabd17e144ed8665bc735940c869
Publikováno v:
Investigational New Drugs. 36:75-84
Patients receiving pegfilgrastim (Neulasta®) for the treatment of neutropenia can experience bone pain following the injections required to achieve effective neutrophil levels. The safety, pharmacokinetic (PK), and pharmacodynamic (PD) profiles of A
Publikováno v:
Artificial cells, nanomedicine, and biotechnology. 47(1)
Hypoxia drives sickle cell disease (SCD) by inducing sickle cell haemoglobin to polymerize and deform red blood cells (RBC) into the sickle shape. A novel carboxyhaemoglobin-based oxygen carrier (PEG-COHb; PP-007) promotes unsickling in vitro by reli
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 38(5)
Similar to patients with chronic hypertension, spontaneously hypertensive rats (SHR) develop fast core progression during middle cerebral artery occlusion (MCAO) resulting in large final infarct volumes. We investigated the effect of Sanguinate™ (S
Publikováno v:
Stroke. 48
Background: The PEGylated cell-free carboxyhemoglobin gas exchanger Sanguinate TM (SG) has multiple beneficial actions that may improve stroke outcome including anti-inflammatory, vasodilatory and oxygen delivery capacity. We investigated the ability
Autor:
Peter L. Collins, Cindy Luongo, Ursula J. Buchholz, Ronald G. Jubin, Maria B. dos Santos, Cyril Le Nouën, Lynnsie M. Schramm, Philippa Hillyer, Lei Huang, Ronald L. Rabin, Lihan Yan, Aaron Chen, Viraj P. Mane, Rachel Shepard
Publikováno v:
Virology. 504
Whether respiratory syncytial virus (RSV) induces severe infantile pulmonary disease may depend on viral strain and expression of types I and III interferons (IFNs). These IFNs impact disease severity by inducing expression of many anti-viral IFN-sti
Autor:
Srikant Bykadi, Philippa Hillyer, Ronald L. Rabin, Viraj P. Mane, Daniela Verthelyi, Ronald G Jubin, Maria B Navarro, Lynnsie M. Schramm, Aaron Chen, Kevin D. Kirschman, Zeng Zhao, Montserrat Puig
Publikováno v:
Immunology and Cell Biology
Recent genome-wide association studies suggest distinct roles for 12 human interferon-alpha (IFN-α) and 3 IFN-λ subtypes that may be elucidated by defining the expression patterns of these sets of genes. To overcome the impediment of high homology
Autor:
Mohammad Salajegheh, Remedios Nazareno, Anne P. Liao, Chris Morehouse, Ronald G. Jubin, Yihong Yao, Steven A. Greenberg, Bahija Jallal
Publikováno v:
Clinical Immunology. 136:130-138
To determine the potential consequences of plasmacytoid dendritic cell (pDC) accumulation in tissue sites observed in several autoimmune diseases, we measured type 1 interferon production from circulating human pDCs as a function of pDC concentration
Autor:
Catherine Buontempo, Peter Buontempo, Ronald G. Jubin, Abraham Abuchowski, Rosa Real, Faiza Adeel, Friedericke Kazo, Siobhan O'Brien
Publikováno v:
Blood. 130:969-969
Background: Pain during Vaso-Occlusive Crisis (VOC) is a hallmark of sickle cell disease (SCD) as deoxygenated (sickled) red blood cells (RBC) aggregate in the microvasculature due to Hemoglobin S (HbS) polymerization. PEGylated carboxyhemoglobin bov