Zobrazeno 1 - 10
of 543
pro vyhledávání: '"Ronald G. Tompkins"'
Autor:
Galit H. Frydman, Felix Ellett, Julianne Jorgensen, Anika L. Marand, Lawrence Zukerberg, Martin K. Selig, Shannon N. Tessier, Keith H. K. Wong, David Olaleye, Charles R. Vanderburg, James G. Fox, Ronald G. Tompkins, Daniel Irimia
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Megakaryocytes (MKs) are precursors to platelets, the second most abundant cells in the peripheral circulation. However, while platelets are known to participate in immune responses and play significant functions during infections, the role of MKs wi
Externí odkaz:
https://doaj.org/article/b06f5c29384149ba997a482d68021238
Autor:
Amy Tsurumi, Patrick J. Flaherty, Yok-Ai Que, Colleen M. Ryan, April E. Mendoza, Marianna Almpani, Arunava Bandyopadhaya, Asako Ogura, Yashoda V. Dhole, Laura F. Goodfield, Ronald G. Tompkins, Laurence G. Rahme
Publikováno v:
iScience, Vol 23, Iss 11, Pp 101659- (2020)
Summary: Severe trauma predisposes patients to multiple independent infection episodes (MIIEs), leading to augmented morbidity and mortality. We developed a method to identify increased MIIE risk before clinical signs appear, which is fundamentally d
Externí odkaz:
https://doaj.org/article/864155cdf78941efb79053fabe299989
Autor:
Harumasa Nakazawa, Kazuhiro Ikeda, Shohei Shinozaki, Masayuki Kobayashi, Yuichi Ikegami, Ming Fu, Tomoyuki Nakamura, Shingo Yasuhara, Yong-Ming Yu, J. A. Jeevendra Martyn, Ronald G. Tompkins, Kentaro Shimokado, Tomoko Yorozu, Hideki Ito, Satoshi Inoue, Masao Kaneki
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Metabolic derangements are a clinically significant complication of major trauma (e.g., burn injury) and include various aspects of metabolism, such as insulin resistance, muscle wasting, mitochondrial dysfunction and hyperlactatemia. Noneth
Externí odkaz:
https://doaj.org/article/afe79a61568341ec8376c8fb9c5a6d31
Autor:
Marianna Almpani, Amy Tsurumi, Thomas Peponis, Yashoda V Dhole, Laura F Goodfield, Ronald G Tompkins, Laurence G Rahme
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0232175 (2020)
Trauma patients are at risk of repeated hospital-acquired infections, however predictive scores aiming to identify susceptibility to such infections are lacking. The objective of this study was to investigate whether commonly employed disease-severit
Externí odkaz:
https://doaj.org/article/8ab89545544e4472891a20f787c6c0ed
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226425 (2019)
PurposeMortality and morbidity rates of elderly burn patients remain high despite numerous advancements in modern burn care. While prior studies have offered first insights on the biochemical changes in elderly burn patients compared to adults, the u
Externí odkaz:
https://doaj.org/article/076d5c855e0949c1b305804be8b556c2
Autor:
Amy Tsurumi, Patrick J. Flaherty, Yok-Ai Que, Colleen M. Ryan, Ankita Banerjee, Arijit Chakraborty, Marianna Almpani, Malavika Shankar, Jeremy Goverman, John T. Schulz, Robert L. Sheridan, Jonathan Friedstat, Sean A. Hickey, Ronald G. Tompkins, Laurence G. Rahme
Publikováno v:
Shock (Augusta, Ga.).
Despite significant advances in pediatric burn care, bloodstream infections (BSIs) remain a compelling challenge during recovery. A personalized medicine approach for accurate prediction of BSIs before they occur would contribute to prevention effort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c69260ddf47bc16e77e76d12f39f324
https://pubmed.ncbi.nlm.nih.gov/36597771
https://pubmed.ncbi.nlm.nih.gov/36597771
Autor:
Zhe-Wei Fei, Vernon R Young, Xiao-Ming Lu, Andrew B Rhodes, Ronald G Tompkins, Alan J Fischman, Yong-Ming Yu
Publikováno v:
Burns & Trauma, Vol 1, Iss 2, Pp 87-94 (2013)
Previous studies from our laboratories revealed a reduced rate of whole-blood (WB) glutathione (GSH) synthesis in severely burned patients. To determine whether WB GSH metabolism is an indicator of the status of GSH metabolism in one or more of the m
Externí odkaz:
https://doaj.org/article/8b3d496470d443ec9d646049af30bbbd
Autor:
Harumasa Nakazawa, Kyungho Chang, Shohei Shinozaki, Takashi Yasukawa, Kazuhiro Ishimaru, Shingo Yasuhara, Yong-Ming Yu, J A Jeevendra Martyn, Ronald G Tompkins, Kentaro Shimokado, Masao Kaneki
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170391 (2017)
Inflammation and apoptosis develop in skeletal muscle after major trauma, including burn injury, and play a pivotal role in insulin resistance and muscle wasting. We and others have shown that inducible nitric oxide synthase (iNOS), a major mediator
Externí odkaz:
https://doaj.org/article/14c5f0c8233b4e7d8f0091f301afeab0
Publikováno v:
Frontiers in Public Health, Vol 4 (2016)
Severe burn injury renders patients susceptible to multiple infection episodes, however identifying specific patient groups at high risk remains challenging. Burn-induced inflammatory response dramatically modifies the levels of various cytokines. Wh
Externí odkaz:
https://doaj.org/article/078b29b1eec74af88e9aa7f005a6f00c
Autor:
John N. Constantino, Patricia L. Kohl, Ellie Wideman, Mini Tandon, Angela Recktenwald, Ronald G. Tompkins, Melissa Jonson-Reid, Allison Dunnigan
Publikováno v:
Public Health Nursing. 37:234-242
Objective Nurse home visiting may address challenges and resource disparities that threaten maternal and infant well-being in rural areas, but little is known about United States' program implementation. This qualitative study explored how family and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6162db852306877e30931d4aae133a0
https://doi.org/10.1111/phn.12699
https://doi.org/10.1111/phn.12699