Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Ronald E. Yasbin"'
Autor:
Norberto Villegas-Negrete, Eduardo A Robleto, Armando Obregón-Herrera, Ronald E Yasbin, Mario Pedraza-Reyes
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179625 (2017)
A forward mutagenesis system based on the acquisition of mutations that inactivate the thymidylate synthase gene (TMS) and confer a trimethoprim resistant (Tmpr) phenotype was developed and utilized to study transcription-mediated mutagenesis (TMM).
Externí odkaz:
https://doaj.org/article/7f5aa4210b22469a8818294ec152c218
Autor:
Ronald E. Yasbin, Norberto Villegas-Negrete, Eduardo A. Robleto, Karen Abundiz-Yañez, Mario Pedraza-Reyes, Hilda C. Leyva-Sánchez
Publikováno v:
J Bacteriol
We report that the absence of an oxidized guanine (GO) system or the apurinic/apyrimidinic (AP) endonucleases Nfo, ExoA, and Nth promoted stress-associated mutagenesis (SAM) in Bacillus subtilis YB955 (hisC952 metB5 leuC427). Moreover, MutY-promoted
Publikováno v:
Current Microbiology. 73:721-726
Compelling evidence point to transcriptional processes as important factors contributing to stationary-phase associated mutagenesis. However, it has not been documented whether or not base excision repair mechanisms play a role in modulating mutagene
Publikováno v:
Journal of Bacteriology. 199
The Gram-positive microorganism Bacillus subtilis relies on a single class Ib ribonucleotide reductase (RNR) to generate 2′-deoxyribonucleotides (dNDPs) for DNA replication and repair. In this work, we investigated the influence of RNR levels on B.
Autor:
Mario Pedraza-Reyes, Víctor M. Ayala-García, Rocío del Carmen Barajas-Ornelas, Eduardo A. Robleto, Fernando H. Ramírez-Guadiana, Ronald E. Yasbin
Publikováno v:
Molecular Microbiology. 90:1088-1099
Summary In conditions of halted or limited genome replication, like those experienced in sporulating cells of Bacillus subtilis, a more immediate detriment caused by DNA damage is altering the transcriptional programme that drives this developmental
Autor:
Holly Anne Martin, Mario Pedraza-Reyes, Amanda A. Kidman, Ronald E. Yasbin, Mary E Girard, Carmen Vallin, Martha Gómez-Marroquín, Amber Pepper, Eduardo A. Robleto
Publikováno v:
Genes; Volume 7; Issue 7; Pages: 33
Genes
Genes, Vol 7, Iss 7, p 33 (2016)
Genes
Genes, Vol 7, Iss 7, p 33 (2016)
In replication-limited cells of Bacillus subtilis, Mfd is mutagenic at highly transcribed regions, even in the absence of bulky DNA lesions. However, the mechanism leading to increased mutagenesis through Mfd remains currently unknown. Here, we repor
Publikováno v:
Microbial Physiology. 21:45-58
In recent years, it has been proposed that conflicts between transcription and active chromosomal replication engender genome instability events. Furthermore, transcription elongation factors have been reported to prevent conflicts between transcript
Autor:
Mariana Ramírez, Luz E. Vidales, Ronald E. Yasbin, Rosario Ramírez, Eduardo A. Robleto, Mario Pedraza-Reyes, Bernardo N. Debora
Publikováno v:
Journal of Bacteriology. 193:236-245
Stress-promoted mutations that occur in nondividing cells (adaptive mutations) have been implicated strongly in causing genetic variability as well as in species survival and evolutionary processes. Oxidative stress-induced DNA damage has been associ
Publikováno v:
Critical Reviews in Biochemistry and Molecular Biology. 42:327-339
One of the experimental platforms to study programs increasing genetic diversity in cells under stressful or nondividing conditions is adaptive mutagenesis, also called stationary phase mutagenesis or stress-induced mutagenesis. In some model systems
Publikováno v:
Journal of Bacteriology. 185:2153-2160
YqjH and YqjW are Bacillus subtilis homologs of the UmuC/DinB or Y superfamily of DNA polymerases that are involved in SOS-induced mutagenesis in Escherichia coli . While the functions of YqjH and YqjW in B . subtilis are still unclear, the compariso