Contributors to the First and Second Editions

Autor: Earl G. Alley, William H. Benson, William O. Berndt, Thomas W. Bouldin, Alan Brimfield, Leslee D. Brown, Lewis R. Brown, Jerry Browne, Philip Carl, Franklin R. Champlin, Howard Chambers, Janice E. Chambers, Lorris G. Cockerham, Robert K. Collins, Sue Conly-Danehower, Jon C. Cook, Nancy M. Cox, Kevin M. Crofton, Walter C. Dauterman, Walter J. Diehl, Donald N. Downer, Laurence Fishbein, Joyce E. Goldstein, Frank E. Guthrie, Doyle Graham, Raymond E. Grissom, John E. Harkness, Ernest Hodgson, Mary E. Hodgson, Clinton D. Kilts, Renate D. Kimbrough, Steven Kinsler, John S. Kizer, Cindy P. Lawler, Ross B. Leidy, Ann T. Lemley, Patricia E. Levi, Margaret Lewandowski, Mark H. Lewis, Kim E. Light, Morris A. Lipton, Richard B. Mailman, Beth Mileson, Pierre Morell, Toshio Narahashi, David E. Nichols, Deborah L. Novicki, Jerome J. Perry, Mario Perez-Reyes, Gary Peterson, Stephen B. Pruett, T. Wayne Schultz, Tony M. Shih, Ivin S. Silver, Gary Smith, Ronald E. Tynes, Mary Vore, Charles A. Waggoner, Quentin D. Walker, William Wargin, Charles L. Wax, John H. Weisburger, Christopher F. Wilkinson, Gary M. Williams, Dwayne A. Wise, John F. Young

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::709b8e81cfdacfdc90944b9024083d13
https://doi.org/10.1016/b978-0-12-420169-9.00033-3

Kinetic Analysis of the Activation of 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone by Heterologously Expressed Human P450 Enzymes and the Effect of P450- Specific Chemical Inhibitors on This Activation in Human Liver Microsomes

Autor: Patrick Koch, Theresa J. Smith, Chung S. Yang, Ronald E. Tynes, Christopher J. Patten, Mong Heng Wang, Sharon E. Murphy, Jae Lee

Publikováno v: Archives of Biochemistry and Biophysics. 333:127-138

The tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is enzymatically activated by the hydroxylation of the alpha-methyl and alpha-methylene groups, leading to the formation of reactive species which can pyridyloxobutylate and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af108612b4c72af00d3802164d9faf32
https://doi.org/10.1006/abbi.1996.0373

Substrate specificity of the rat liver Na(+)-bile salt cotransporter in Xenopus laevis oocytes and in CHO cells

Autor: Bruno Hagenbuch, Alice Schroeder, Uta Eckhardt, Peter J. Meier, Claudio D. Schteingart, Alan F. Hofmann, Ronald E. Tynes, Bruno Stieger

Publikováno v: The American journal of physiology. 274(2)

It has been proposed that the hepatocellular Na+-dependent bile salt uptake system exhibits a broad substrate specificity in intact hepatocytes. In contrast, recent expression studies in mammalian cell lines have suggested that the cloned rat liver N

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6249301d9abf5c609394f45e381591ef
https://pubmed.ncbi.nlm.nih.gov/9486191

Oxidation of thiobenzamide by the fad-containing and cytochrome P-450-dependent monooxygenases of liver and lung microsomes

Autor: Ronald E. Tynes, Ernest Hodgson

Publikováno v: Biochemical Pharmacology. 32:3419-3428

Two distinct microsomal pathways involved in the metabolism of thiobenzamide to thiobenzamide S -oxide have been identified and quantitated in the liver and lungs of mice and rats, using a highly inhibitory antibody against NADPH-cytochrome P-450 red

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ea1cac6ab0f24041705a4ee8c03630
https://doi.org/10.1016/0006-2952(83)90371-4

Magnitude of involvement of the mammalian flavin-containing monooxygenase in the microsomal oxidation of pesticides

Autor: Ernest Hodgson, Ronald E. Tynes

Publikováno v: Journal of Agricultural and Food Chemistry. 33:471-479

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5160d71d5f976d3e6b1498e436e3123
https://doi.org/10.1021/jf00063a036