Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ronald E. Hileman"'
Autor:
Richard E. Goodman, Gary A. Bannon, Elena A. Rice, Ronald E. Hileman, James D. Astwood, Andre Silvanovich
Publikováno v:
Comments on Toxicology. 8:251-269
(2002). Bioinformatic Methods for Identifying Known or Potential Allergens in the Safety Assessment of Genetically Modified Crops. Comments on Toxicology: Vol. 8, No. 3, pp. 251-269.
Autor:
Tidly Ping, Sandra M. Wice, Linda M. Hiebert, Ronald E. Hileman, Tfilay Polat, Robert J. Linhardt
Publikováno v:
Pharmaceutical Research. 19:838-844
Purpose. Aluminum sucrose octasulfate (SOS) is used clinically to prevent ulcers. Under physiologic conditions, the sodium salt of this drug can be formed. Our objective was to determine whether sodium SOS was absorbed when administered orally. In ad
Autor:
James D. Astwood, Elena A. Rice, Gyula Holleschak, Susan L. Hefle, Andre Silvanovich, Ronald E. Hileman, Richard E. Goodman
Publikováno v:
International Archives of Allergy and Immunology. 128:280-291
Background: A principal aim of the safety assessment of genetically modified crops is to prevent the introduction of known or clinically cross-reactive allergens. Current bioinformatic tools and a database of allergens and gliadins were tested for th
Autor:
Linda M Hiebert, Sandra M Wice, Tilly Ping, Ronald E Hileman, Ishan Capila, Robert J Linhardt
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 78:307-320
Distribution and antithrombotic activity of orally administered unfractionated porcine heparin were studied. [14C]Heparin was prepared by de-N-acetylation of porcine mucosal heparin followed by re-N-acetylation, using [14C]acetic anhydride. [14C]Hepa
Autor:
Sandra M. Wice, Ishan Capila, Linda M. Hiebert, Ronald E. Hileman, Robert J. Linhardt, Tilly Ping
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 78:307-320
Distribution and antithrombotic activity of orally administered unfractionated porcine heparin were studied. [14C]Heparin was prepared by de-N-acetylation of porcine mucosal heparin followed by re-N-acetylation, using [14C]acetic anhydride. [14C]Hepa
Publikováno v:
BioEssays. 20:156-167
Although interactions of proteins with glycosaminoglycans (GAGs), such as heparin and heparan sulphate, are of great biological importance, structural requirements for protein-GAG binding have not been well-characterised. Ionic interactions are impor
Publikováno v:
Biochemistry. 37:15231-15237
Brain natriuretic peptide (BNP) was examined as part of a continuing study of the interaction of proteins and peptides with the glycosaminoglycan heparin. BNP was tentatively identified as a heparin-binding protein on the basis of its cyclic structur
Autor:
Xiaojun Wu, Robert J. Linhardt, Clifford D. Wright, Ronald E. Hileman, William M. Abraham, Melissa A. Fath, Richard M. Nelson, Mohammed A. Kashem
Publikováno v:
Journal of Biological Chemistry. 273:13563-13569
Protease inhibition by secretory leukocyte protease inhibitor (SLPI) is accelerated by the sulfated polysaccharides. The nature of the SLPI-polysaccharide interaction, explored with affinity chromatography, indicated that this interaction was sensiti
Publikováno v:
Electrophoresis. 19:437-441
A new capillary electrophoresis technique has been developed for the affinity resolution of synthetic heparin-binding peptides using an immobilized glycosaminoglycan. Heparin and heparan sulfate were immobilized onto fused silica capillaries using bi
Autor:
Jonathan R. Fromm, Robert J. Linhardt, Terry Maguire, Ronald E. Hileman, Jeffrey D. Esko, Rory M. Marks, Yaping Chen
Publikováno v:
Nature Medicine. 3:866-871
Dengue virus is a human pathogen that has reemerged as an increasingly important public health threat. We found that the cellular receptor utilized by dengue envelope protein to bind to target cells is a highly sulfated type of heparan sulfate. Hepar