Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ronald E. Esser"'
Autor:
Richard A. Angelo, Lynnetta M. Watts, Ronald E. Esser, Mark D. Murphey, Alan R. Hildebrand, Larry E. Baugh
Publikováno v:
Arthritis & Rheumatism. 38:129-138
Objective. To apply quantitative analytical methods to the evaluation of radiographic images in experimental arthritis. Methods. Adjuvant was used to induce arthritis in rats. Arthritis progression was followed by conventional methods. In addition, d
Autor:
Robert E. Smith, Richard A. Angelo, Larry P. Thornburg, Mark D. Murphey, Jamil W. Talhouk, James T. Palmer, Ronald E. Esser, Lynnetta M. Watts
Publikováno v:
Arthritis & Rheumatism. 37:236-247
Objective. To determine the effects of peptidyl fluoromethyl ketones on the in vitro activity of purified cathepsins B and L, on tissue cysteine proteinase activity, and on cartilage and bone destruction in experimental arthritis. Methods. The effect
Autor:
Jeff Prior, Lorene A. Martin, Larry P. Thornburg, Ronald E. Esser, Lynnetta M. Watts, Nahed K. Ahmed, Jim Palmer
Publikováno v:
Biochemical Pharmacology. 44:1201-1207
Peptidyl fluoromethyl ketones (FMKs), with the amino acid sequence Phe-Ala held constant but with variable N-terminal groups, were synthesized and tested for inhibition of the cysteine proteinase cathepsin B. The FMKs were effective in inhibiting cat