Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Ronald E. Engle"'
Autor:
Ronald E. Engle, Davide De Battista, Emily J. Danoff, Hanh Nguyen, Zhaochun Chen, Paolo Lusso, Robert H. Purcell, Patrizia Farci
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT Historical studies conducted in chimpanzees gave us the opportunity to investigate the basis for the different severities of liver damage and disease outcome associated with infection with wild-type hepatitis B virus (HBV) versus a precore H
Externí odkaz:
https://doaj.org/article/768f688d197d4431af1bcf8b0fad35a4
Autor:
Zhaochun Chen, Ronald E Engle, Chen-Hsiang Shen, Huaying Zhao, Peter W Schuck, Emily J Danoff, Hanh Nguyen, Norihisa Nishimura, Kevin W Bock, Ian N Moore, Peter D Kwong, Robert H Purcell, Sugantha Govindarajan, Patrizia Farci
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008793 (2020)
Transmission to chimpanzees of a precore hepatitis B virus (HBV) mutant implicated in acute liver failure (ALF) in humans did not cause ALF nor the classic form of acute hepatitis B (AHB) seen upon infection with the wild-type HBV strain, but rather
Externí odkaz:
https://doaj.org/article/5612fb1e37e748f7a7ed1136e5a4617d
Autor:
Patrizia Farci, David E. Kleiner, Sugantha Govindarajan, Fausto Zamboni, Ian N. Moore, Kevin W. Bock, Michael R. Emmert-Buck, Jeffrey Hanson, Jaime Rodriguez-Canales, Stephanie Montenegro, Marta Melis, Ashley Tice, Ronald E. Engle, Giacomo Diaz
Synopsis of the 20 top-scored pathways associated with WLT-unique genes identified in the three tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb1e889ecb4bfa8d458eacface4c9d5
https://doi.org/10.1158/1541-7786.22515784.v1
https://doi.org/10.1158/1541-7786.22515784.v1
Autor:
Vandana Sekhar, Teresa Pollicino, Giacomo Diaz, Ronald E Engle, Farah Alayli, Marta Melis, Juraj Kabat, Ashley Tice, Anna Pomerenke, Nihal Altan-Bonnet, Fausto Zamboni, Paolo Lusso, Suzanne U Emerson, Patrizia Farci
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006916 (2018)
Entry of hepatitis C virus (HCV) into hepatocytes is a complex process that involves numerous cellular factors, including the scavenger receptor class B type 1 (SR-B1), the tetraspanin CD81, and the tight junction (TJ) proteins claudin-1 (CLDN1) and
Externí odkaz:
https://doaj.org/article/787e8f5e0db9407196241f0eb0ac56ca
Autor:
Shinya Sato, Tovah E. Markowitz, Fausto Zamboni, Ronald E. Engle, Hannah Gerstein, Justin B. Lack, Patrizia Farci, Davide De Battista
Publikováno v:
Journal of Hepatocellular Carcinoma
Davide De Battista,1 Fausto Zamboni,2 Hannah Gerstein,1 Shinya Sato,1 Tovah E Markowitz,3,4 Justin Lack,3,4 Ronald E Engle,1 Patrizia Farci1 1Hepatic Pathogenesis Section, Laboratory of Infectious Diseases, National Institute of Allergy and Infectiou
Autor:
Fausto Zamboni, Zhaochun Chen, Ronald E. Engle, Patrizia Farci, Peter D. Kwong, Robert H. Purcell, Chen-Hsiang Shen
Publikováno v:
Journal of Viral Hepatitis. 27:847-851
Hepatitis B virus (HBV) is a major cause of acute liver failure (ALF) worldwide. While liver damage in classic acute hepatitis B is believed to be T-cell mediated, the pathogenesis of HBV-associated ALF remains largely unknown. Access to liver specim
Autor:
Robert John Fontana, Ronald E. Engle, Paul H. Hayashi, Jiezhun Gu, David E. Kleiner, Hahn Nguyen, Huiman Barnhart, Jay H. Hoofnagle, Patrizia Farci
Publikováno v:
The American journal of gastroenterology. 117(9)
Hepatitis E virus (HEV) infection rarely causes icteric hepatitis, yet 10%-40% of adult Americans have serological evidence of previous infection. The aim of this study was to investigate the incidence, presentation, and outcome of acute and previous
Autor:
Robert H. Purcell, Ronald E. Engle, Michael P. Rood, Yamina Kabrane-Lazizi, Hanh T. Nguyen, Sugantha Govindarajan, Marisa St. Claire, Suzanne U. Emerson
Publikováno v:
Emerging Infectious Diseases, Vol 17, Iss 12, Pp 2216-2222 (2011)
The role of rats in human hepatitis E virus (HEV) infections remains controversial. A genetically distinct HEV was recently isolated from rats in Germany, and its genome was sequenced. We have isolated a genetically similar HEV from urban rats in Los
Externí odkaz:
https://doaj.org/article/cc469e564ce043b280dfa867ac7fd9e2
Autor:
David E. Kleiner, Juraj Kabat, Patrizia Farci, Kevin W. Bock, Rafaelle Fares-Gusmao, Norihisa Nishimura, Shinya Sato, Ashley Tice, Fausto Zamboni, Harvey J. Alter, Ronald E. Engle, Ian N. Moore, Hanh Nguyen, David R. McGivern, Sugantha Govindarajan, Davide De Battista, Anna Pomerenke
Publikováno v:
Proc Natl Acad Sci U S A
Older age at the time of infection with hepatitis viruses is associated with an increased risk of liver fibrosis progression. We hypothesized that the pace of fibrosis progression may reflect changes in gene expression within the aging liver. We comp
Autor:
Emily J. Danoff, Zhaochun Chen, Robert H. Purcell, Davide De Battista, Hanh Nguyen, Paolo Lusso, Ronald E. Engle, Patrizia Farci
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
mBio
mBio
Studies performed in chimpanzees at the National Institutes of Health (NIH) demonstrated a significant difference in ALT levels during acute hepatitis of different viral etiologies, with a hierarchy in the extent of liver damage according to the infe