Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Ronald E Ellis"'
Autor:
Wen Xu, Lijiang Long, Yuehui Zhao, Lewis Stevens, Irene Felipe, Javier Munoz, Ronald E Ellis, Patrick T McGrath
Publikováno v:
eLife, Vol 8 (2019)
Genes can encode multiple isoforms, broadening their functions and providing a molecular substrate to evolve phenotypic diversity. Evolution of isoform function is a potential route to adapt to new environments. Here we show that de novo, beneficial
Externí odkaz:
https://doaj.org/article/5d9d57b73a374789ba05e2132e587ffd
Autor:
Yanmei Zhao, Chieh-Hsiang Tan, Amber Krauchunas, Andrea Scharf, Nicholas Dietrich, Kurt Warnhoff, Zhiheng Yuan, Marina Druzhinina, Sam Guoping Gu, Long Miao, Andrew Singson, Ronald E Ellis, Kerry Kornfeld
Publikováno v:
PLoS Biology, Vol 16, Iss 6, p e2005069 (2018)
Sperm activation is a fascinating example of cell differentiation, in which immotile spermatids undergo a rapid and dramatic transition to become mature, motile sperm. Because the sperm nucleus is transcriptionally silent, this transition does not in
Externí odkaz:
https://doaj.org/article/95ef2d03bedb46e392edb80c63246d45
Autor:
Ronald E Ellis, Qing Wei
Publikováno v:
eLife, Vol 4 (2015)
Male nematode worms may make larger sperm than hermaphrodite worms, but this is not the only reason that sperm from males have a competitive edge.
Externí odkaz:
https://doaj.org/article/e7246f0ca16d45d2b59943a5d11d67cb
Autor:
Ronald E Ellis, Lukas Schärer
Publikováno v:
PLoS Biology, Vol 12, Iss 7, p e1001916 (2014)
Intense reproductive competition often continues long after animals finish mating. In many species, sperm from one male compete with those from others to find and fertilize oocytes. Since this competition occurs inside the female reproductive tract,
Externí odkaz:
https://doaj.org/article/0f1e246fbbc04254907496531276599e
Publikováno v:
PLoS Genetics, Vol 9, Iss 10, p e1003850 (2013)
A subset of transcription factors like Gli2 and Oct1 are bipotential--they can activate or repress the same target, in response to changing signals from upstream genes. Some previous studies implied that the sex-determination protein TRA-1 might also
Externí odkaz:
https://doaj.org/article/4cf792aa32654fbca959c90d90fb82b2
Autor:
Sara Andux, Ronald E Ellis
Publikováno v:
PLoS Genetics, Vol 4, Iss 12, p e1000295 (2008)
In women, oocytes arrest development at the end of prophase of meiosis I and remain quiescent for years. Over time, the quality and quantity of these oocytes decreases, resulting in fewer pregnancies and an increased occurrence of birth defects. We u
Externí odkaz:
https://doaj.org/article/09b0848b3925432bb66fd7b7112fe635
Publikováno v:
PLoS Genetics, Vol 1, Iss 3, p e37 (2005)
The unfolded protein response (UPR) is an adaptive signaling pathway utilized to sense and alleviate the stress of protein folding in the endoplasmic reticulum (ER). In mammals, the UPR is mediated through three proximal sensors PERK/PEK, IRE1, and A
Externí odkaz:
https://doaj.org/article/11d5ed558e4c4bfc92d1ff3ae3666207
Publikováno v:
microPublication biology. 2022
To learn if orthologous mutations are temperature-sensitive in related species, we studied four
Autor:
Ronald E. Ellis
Publikováno v:
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation.
Background: Animal germ cells differentiate as sperm or as oocytes. These sexual fates are controlled by complex regulatory pathways to ensure that the proper gametes are made at the appropriate times. Summary: Nematodes like Caenorhabditis elegans a
Autor:
Ronald E. Ellis
Publikováno v:
Current Biology. 30:R1314-R1316
Changing how hormones regulate development can influence the complex trade-offs involved in the competition to survive and reproduce. A new report identifies a molecular variant of eak-3 that trades lower growth rates for the ability to survive sudde