Výsledky vyhledávání - "Ronald DeMatteo"

Akademický článek

Identification of Wee1 as a target in combination with avapritinib for gastrointestinal stromal tumor treatment

Autor: Shuai Ye, Dinara Sharipova, Marya Kozinova, Lilli Klug, Jimson D’Souza, Martin G. Belinsky, Katherine J. Johnson, Margret B. Einarson, Karthik Devarajan, Yan Zhou, Samuel Litwin, Michael C. Heinrich, Ronald DeMatteo, Margaret von Mehren, James S. Duncan, Lori Rink

Publikováno v: JCI Insight, Vol 6, Iss 2 (2021)

Management of gastrointestinal stromal tumors (GISTs) has been revolutionized by the identification of activating mutations in KIT and PDGFRA and clinical application of RTK inhibitors in advanced disease. Stratification of GISTs into molecularly def

Externí odkaz: https://doaj.org/article/bc77aa077101497c8a5b94060a37a94d

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Akademický článek

Combined ablation and resection (CARe) as an effective parenchymal sparing treatment for extensive colorectal liver metastases.

Autor: Serge Evrard, Graeme Poston, Peter Kissmeyer-Nielsen, Abou Diallo, Grégoire Desolneux, Véronique Brouste, Caroline Lalet, Frank Mortensen, Stefan Stättner, Stephen Fenwick, Hassan Malik, Ioannis Konstantinidis, Ronald DeMatteo, Michael D'Angelica, Peter Allen, William Jarnagin, Simone Mathoulin-Pelissier, Yuman Fong

Publikováno v: PLoS ONE, Vol 9, Iss 12, p e114404 (2014)

Combined intra-operative ablation and resection (CARe) is proposed to treat extensive colorectal liver metastases (CLM). This multicenter study was conducted to evaluate overall survival (OS), local recurrence-free survival (LRFS), hepatic recurrence

Externí odkaz: https://doaj.org/article/5022a3ff066f42508fd801ff4c3e18ed

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Akademický článek

Gastrointestinal stromal tumors, somatic mutations and candidate genetic risk variants.

Autor: Katie M O'Brien, Irene Orlow, Cristina R Antonescu, Karla Ballman, Linda McCall, Ronald DeMatteo, Lawrence S Engel

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e62119 (2013)

Gastrointestinal stromal tumors (GISTs) are rare but treatable soft tissue sarcomas. Nearly all GISTs have somatic mutations in either the KIT or PDGFRA gene, but there are no known inherited genetic risk factors. We assessed the relationship between

Externí odkaz: https://doaj.org/article/3a2d1eb7b72842ec82370efffb72011d

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Abstract P050: Oncogenic kinase therapy restricts CD8 T cell differentiation and clonal expansion

Autor: Andrew Tieniber, Andrew Hanna, Benjamin Medina, Kevin Do, Lillian Levin, Ferdiando Rossi, Ronald DeMatteo

Publikováno v: Cancer Immunology Research. 10:P050-P050

Introduction: Targeted therapy with tyrosine kinase inhibitors (TKI) including imatinib is effective in treating gastrointestinal stromal tumor (GIST), but resistance often develops within 18 months. Despite a robust immune T cell infiltrate, combini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ce7ea58ef4215be67ce544e271f58ce
https://doi.org/10.1158/2326-6074.tumimm21-p050

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Elektronická kniha

100 Questions & Answers About Liver Cancer

Autor: Ghassan K. Abou-Alfa, Ronald DeMatteo

Providing both doctor and patient perspectives, this updated edition offers authoritative answers to the most commonly asked questions about liver cancer including diagnosis, treatment, post-treatment quality of life, and coping strategies. Written b

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Comparative 'nocebo effects' in older patients enrolled in cancer therapeutic trials: Observations from a 446-patient cohort

Autor: Jared C, Foster, Jennifer G, Le-Rademacher, Josephine L, Feliciano, Ajeet, Gajra, Drew K, Seisler, Ronald, DeMatteo, Jacqueline M, Lafky, Arti, Hurria, Hyman B, Muss, Harvey J, Cohen, Aminah, Jatoi

Publikováno v: Cancer. 123(21)

A nocebo is an inert substance associated with adverse events. Although previous studies have examined the positive (placebo) effects of such inert substances, few have examined negative (nocebo) adverse event profiles, particularly in older patients

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::54332b2beb3bca9deaae0f68df8cb7ad
https://pubmed.ncbi.nlm.nih.gov/28700816

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