Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ronald D. Poretz"'
Autor:
Ronald D. Poretz, Wenbin Deng
Publikováno v:
NeuroToxicology. 22:429-437
Lead is a neurotoxicant that can cause myelin deficits. Galactolipids are expressed during differentiation of oligodendrocyte lineage cells and accumulate in myelin. To examine the impact of lead on oligodendroglial differentiation, galactolipid meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496fcb857a6bddeee7e71a03344e1edb
https://doi.org/10.1016/s0161-813x(01)00048-1
https://doi.org/10.1016/s0161-813x(01)00048-1
Publikováno v:
Teratogenesis, Carcinogenesis, and Mutagenesis. 19:313-322
Much attention in recent years has been given to the antigenotoxicity of chlorophyll. Chlorophyll, however, is known to be converted into pheophytin, pyropheophytin, and pheophorbide in processed vegetable food and following ingestion by humans. Stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce1988a1c3aea6119a5072684a227bc2
https://doi.org/10.1002/(sici)1520-6866(1999)19:5<313::aid-tcm1>3.0.co
https://doi.org/10.1002/(sici)1520-6866(1999)19:5<313::aid-tcm1>3.0.co
Publikováno v:
Alcoholism: Clinical and Experimental Research. 20:228-233
The IIIa and IIIb electrophoretic variants of arylsulfatase A (EC 3.1.6.8) are 12 times more prevalent in alcoholic than in nonalcoholic populations. These variant enzymes, found in a subset of alcoholics, possess the pseudodeficient Asn350-Ser mutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baac9c527ebc50336027e7a2b50f1223
https://doi.org/10.1111/j.1530-0277.1996.tb01634.x
https://doi.org/10.1111/j.1530-0277.1996.tb01634.x
Publikováno v:
Biochemical Genetics. 34:149-161
Previous work has shown that specific electrophoretic variants of arylsulfatase A occur more frequently among alcoholic patients than among psychiatric and normal controls. The present study sequenced the gene for two of these electrophoretic variant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598a904170f516cf122f2ca925866d96
https://doi.org/10.1007/bf02396247
https://doi.org/10.1007/bf02396247
Publikováno v:
Alcoholism: Clinical and Experimental Research. 20:234-239
Several electrophoretic forms of human platelet arylsulfatase A (ASA), including variant type III a and normal type IV a , have been identified by nondenaturing polyacrylamide gel electrophoresis. An alcoholic population that we have analyzed is enri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bebb4f4cd822d4a82b16adb2212388d
https://doi.org/10.1111/j.1530-0277.1996.tb01635.x
https://doi.org/10.1111/j.1530-0277.1996.tb01635.x
Publikováno v:
Biochemical Journal. 287:979-983
Human platelet arylsulphatase A (ASA) exhibits a multiple banding pattern when examined by PAGE. The isoform pattern (IVa) of the enzyme obtained from normal subjects differs from variants (IIIa, IIIb, IVb) which are primarily found in alcoholic pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed685a3ee5f48aef75fb26dfb01c55c5
https://doi.org/10.1042/bj2870979
https://doi.org/10.1042/bj2870979
Publikováno v:
Journal of AOAC INTERNATIONAL. 80:433-435
A reversed-phase liquid chromatographic (LC) system with photodiode array detection was used to analyze chlorophyllin copper complex (CCC). Analysis revealed significant differences in the porphyrin compositions of CCC samples from 5 industrial sourc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b934c9d69ab06594f79c60a3b6213eb8
https://doi.org/10.1093/jaoac/80.2.433
https://doi.org/10.1093/jaoac/80.2.433
Autor:
Wenbin Deng, Ronald D. Poretz
Publikováno v:
Brain research. 929(1)
Lead (Pb) is a common neurotoxicant of major public health concern. Previous studies revealed that cultured oligodendrocyte progenitor cells (OPCs) are highly vulnerable to Pb toxicity. The present study examines the effect of Pb on the survival, pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f518fba15cdad6dc21424988a6efa970
https://pubmed.ncbi.nlm.nih.gov/11852034
https://pubmed.ncbi.nlm.nih.gov/11852034
Autor:
Ronald D. Poretz, Xiao G. Chen
Publikováno v:
Toxicology. 163(2-3)
Lead exposure causes cognitive and behavioral deficits in some children. We have proposed that the effects of single nucleotide polymorphisms (SNP) of the human pseudodeficient arylsulfatase A (ARSA) gene that result in reduced levels of the enzyme,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166521197ca528316fad2d464bff2354
https://pubmed.ncbi.nlm.nih.gov/11516520
https://pubmed.ncbi.nlm.nih.gov/11516520
Publikováno v:
Toxicology and applied pharmacology. 174(3)
Lead (Pb) is an environmental neurotoxicant that can cause hypo- and demyelination. Oligodendrocytes (OLs), the myelin-forming cells in the central nervous system, may be a possible target for Pb toxicity. The present study describes the effect of Pb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db85b5dfe7f98df209fbbb409abea57
https://pubmed.ncbi.nlm.nih.gov/11485384
https://pubmed.ncbi.nlm.nih.gov/11485384