Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ronald D. Graff"'
Publikováno v:
The Spine Journal. 13:439-442
Background context Methylprednisolone (MP) infusion after acute spinal cord injury (SCI) remains controversial despite large randomized studies, including the National Acute Spinal Cord Injury Studies (NASCIS). Purpose To determine the effect of NASC
Publikováno v:
Journal of Biomaterials Applications. 27:1046-1054
Avascularity and hypoxia result in avascular necrosis and play a negative role in fracture healing. The FDA-approved iron chelating agent, desferoxamine (DFO) in a liquid form, has been shown to induce angiogenesis and improve fracture healing throug
Publikováno v:
Arthritis & Rheumatism. 48:2722-2736
Autor:
Ronald D. Graff, Greta M. Lee
Publikováno v:
Analytical Biochemistry. 318:181-186
For studying mechanotransduction in cultured cells, we developed a microplate assay using a fluorescence/luminescence plate reader equipped with software-controlled injectors to deliver a reproducible mechanical stimulus (adjustable for both timing a
Publikováno v:
Current Opinion in Rheumatology. 15:315-320
Nucleotides are released by chondrocytes at rest and in response to mechanical stimulation. Extracellular nucleotides are metabolized by a variety of ectoenzymes, producing free phosphate (Pi) or pyrophosphate (PPi) and promoting matrix mineralizatio
Autor:
Scott S. Kelley, Peiyuan Lin, Marilyn Jansen, Marianne E. Tioran, Ronald D. Graff, Greta M. Lee
Publikováno v:
Journal of Cellular Physiology. 192:113-124
Interleukin-1 induces release of NO and PGE 2 and production of matrix degrading enzymes in chondrocytes. In osteoarthritis (OA), IL-1 continually, or episodically, acts on chondrocytes in a paracrine and autocrine manner. Human chondrocytes in chond
Publikováno v:
Arthritis & Rheumatism. 43:1571-1579
Objective To determine whether ATP is released from chondrocytes during mechanical stimulation and whether degradation of ATP generates inorganic pyrophosphate in chondron pellet cultures. Methods Chondron pellets were formed from 1.6 × 106 cells th
Publikováno v:
Journal of Neurocytology. 27:119-126
Brain microtubule dynamics were studied by video-enhanced differential interference contrast microscopy in a cytosolic extract from fetal rat brain, prepared under conditions designed to produce minimal alterations in microtubule stability. With urch
Autor:
Ronald D. Graff, Mamoru Kawakami, Satoru Yamazaki, Joe T. Minchew, Mari Tsuzaki, Albert J. Banes, Paul S. Weinhold
Publikováno v:
Journal of cellular biochemistry. 90(4)
Mechanical forces regulate the developmental path and phenotype of a variety of tissues and cultured cells. Vibratory loading as a mechanical stimulus occurs in connective tissues due to energy returned from ground reaction forces, as well as a mecha
Publikováno v:
Arthritis and rheumatism. 48(10)