Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Ronald Chalmers"'
Autor:
Michael Tellier, Ronald Chalmers
Publikováno v:
Mobile DNA, Vol 11, Iss 1, Pp 1-14 (2020)
Abstract Background Transposable elements (TEs) are a diverse group of self-mobilizing DNA elements. Transposition has been exploited as a powerful tool for molecular biology and genomics. However, transposition is sometimes limited because of auto-r
Externí odkaz:
https://doaj.org/article/165d2bbe17854b10a281f4abcbf5678c
Publikováno v:
PLoS Pathogens, Vol 12, Iss 8, p e1005826 (2016)
Little is known about the relative contributions and importance of antibacterial effectors in the nematode C. elegans, despite extensive work on the innate immune responses in this organism. We report an investigation of the expression, function and
Externí odkaz:
https://doaj.org/article/ab3d14185a3447e3bd08bfc931e9628b
Publikováno v:
eLife, Vol 2 (2013)
How do DNA transposons live in harmony with their hosts? Bacteria provide the only documented mechanisms for autoregulation, but these are incompatible with eukaryotic cell biology. Here we show that autoregulation of Hsmar1 operates during assembly
Externí odkaz:
https://doaj.org/article/db23765293094537a08c39a0be2cf272
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53690 (2013)
Hsmar1 is a member of the Tc1-mariner superfamily of DNA transposons. These elements mobilize within the genome of their host by a cut-and-paste mechanism. We have exploited the in vitro reaction provided by Hsmar1 to investigate the effect of DNA su
Externí odkaz:
https://doaj.org/article/ce3b1e94f702484098f25c3dfb9412ae
Autor:
Nicolas Buisine, Ronald Chalmers
Publikováno v:
BioTechniques, Vol 37, Iss 6, Pp 987-989 (2004)
Externí odkaz:
https://doaj.org/article/0ac409dc995d40e6afabf93696d4d2f1
Publikováno v:
PLoS Genetics, Vol 7, Iss 1, p e1001277 (2011)
Neisseria meningitidis is the primary causative agent of bacterial meningitis. The genome is rich in repetitive DNA and almost 2% is occupied by a diminutive transposon called the Correia element. Here we report a bioinformatic analysis defining eigh
Externí odkaz:
https://doaj.org/article/53618dbea7f447db88decc473a8a89cd
Autor:
Julien Bischerour, Ronald Chalmers
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6201 (2009)
The bacterial Tn5 and Tn10 transposases have a single active site that cuts both strands of DNA at their respective transposon ends. This is achieved using a hairpin intermediate that requires the DNA to change conformation during the reaction. In Tn
Externí odkaz:
https://doaj.org/article/0fa1f39a8cb845aa97faf70ed8fdcdf4
Autor:
Ronald Chalmers, Shivam Bhatt
Publikováno v:
Nucleic Acids Research
Homology-directed genome engineering is limited by transgene size. Although DNA transposons are more efficient with large transgenes, random integrations are potentially mutagenic. Here we present an in vitro mechanistic study that demonstrates effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac401a3dedcbdfd31f2ccbbaad4d183
http://europepmc.org/articles/PMC6735945
http://europepmc.org/articles/PMC6735945
Autor:
Ronald Chalmers
When Michael Rorke, a talented yet self-absorbed author, meets his untimely end in an accident, he awakens as a wanderer – a spirit caught between worlds, unsure of what afterlife, be it blissful or grim, lies ahead. In this liminal state, he is un
Autor:
Michael, Tellier, Ronald, Chalmers
Publikováno v:
Mobile DNA
Background Transposable elements (TEs) are a diverse group of self-mobilizing DNA elements. Transposition has been exploited as a powerful tool for molecular biology and genomics. However, transposition is sometimes limited because of auto-regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f93ff49a62cf02b1e88a66873c2a9cd
https://pubmed.ncbi.nlm.nih.gov/31938044
https://pubmed.ncbi.nlm.nih.gov/31938044