Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ronald Carrasquillo-Flores"'
Autor:
Joshua A. Selekman, Robert Wethman, Steven R. Wisniewski, John M. Wasylyk, Vivek Daftary, Joshua Engstrom, Thomas M. Razler, Tamar Rosenbaum, Federico Lora-Gonzalez, Brendan Mack, Ronald Carrasquillo-Flores, Ming-Hsing Huang, Candi Choi
Publikováno v:
Organic Process Research & Development. 25:1028-1035
We show that the behavior of a polymorphic transformation under high shear can be predicted up to pilot scales on the basis of laboratory experiments. Solubility measurements indicate that the tran...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7eb014bb3914200696f2afaafd9bf8fc
https://doi.org/10.1021/acs.oprd.1c00030
https://doi.org/10.1021/acs.oprd.1c00030
Autor:
Jonathan Marshall, Shawn Brueggemeier, Subha Mukherjee, Sloan Ayers, Jun Qiu, Michael J. Smith, Kathleen Kelly, Patricia Cho, Ronald Carrasquillo-Flores, Federico Lora Gonzalez, Gregory L. Beutner
Publikováno v:
Organic Process Research & Development. 24:2709-2721
Research on the development of scalable routes to pharmaceutical intermediates typically proceeds from explorations of the chemistry to the identification of robust procedures for isolation. Althou...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6121e713be93d0a4f5f3ec9036acc403
https://doi.org/10.1021/acs.oprd.0c00374
https://doi.org/10.1021/acs.oprd.0c00374
Autor:
Carolyn S. Higman, Adrian Ortiz, Geoffrey E. Purdum, Ronald Carrasquillo-Flores, Yichen Tan, Kolotuchin Sergei, Steven R. Wisniewski, Thomas C. Malig, Jason E. Hein
Publikováno v:
Reaction Chemistry & Engineering. 5:1421-1428
We have developed a convenient two-step, one-pot method for the facile synthesis of cyanoimidazoles. By integrating a suite of reaction-monitoring techniques, we were able to interrogate each transformation independently. We observed that formation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0df44b6e491e1e6af685ac88f720cf4
https://doi.org/10.1039/d0re00234h
https://doi.org/10.1039/d0re00234h
Autor:
Federico Lora Gonzalez, Jose E. Tabora, Eric C. Huang, Brendan Mack, Steven R. Wisniewski, Thomas M. Razler, Ronald Carrasquillo-Flores
Publikováno v:
Organic Process Research & Development. 23:211-219
In the development process of an active pharmaceutical ingredient (API), determination of the design space used for control of critical quality attributes (CQAs) is a key component of the quality by design (QbD) framework outlined by the regulatory a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35ac3d52f43f387bec6d283480ce13c1
https://doi.org/10.1021/acs.oprd.8b00293
https://doi.org/10.1021/acs.oprd.8b00293
Autor:
Federico Lora Gonzalez, Steven R. Wisniewski, Brendan Mack, Ronald Carrasquillo-Flores, Maxime Soumeillant, Matthew Casey, Thomas M. Razler, Antonio Ramirez
Publikováno v:
Organic Process Research & Development. 22:1426-1431
The final step in the route to BMS-986142, a reversible inhibitor of the BTK enzyme, involves the diastereoselective construction of a chiral axis during the base-mediated cyclization of the quinazolinedione fragment. Optimization of the reaction to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::117e95619df4dbcc06b6518add2a6956
https://doi.org/10.1021/acs.oprd.8b00246
https://doi.org/10.1021/acs.oprd.8b00246
Publikováno v:
Applied Catalysis A: General. 521:182-189
Well characterized AuMo x catalysts were synthesized by controlled surface reactions (CSR) and studied in reverse water gas shift (RWGS) reaction with and without visible light addition. The numbers of Au and Au–Mo interfacial sites on these cataly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6042f95685e61397605182c490eec02c
https://doi.org/10.1016/j.apcata.2015.11.021
https://doi.org/10.1016/j.apcata.2015.11.021
Autor:
Jeffrey T. Miller, Ive Hermans, Carlos A. Carrero, Samuel P. Burt, Ana C. Alba-Rubio, George W. Huber, James A. Dumesic, Ronald Carrasquillo-Flores, Mrunmayi D. Kumbhalkar, Insoo Ro
Publikováno v:
Journal of the American Chemical Society. 137:10317-10325
We show that MoO(x)-promoted Au/SiO2 catalysts are active for reverse water-gas shift (RWGS) at 573 K. Results from reactivity measurements, CO FTIR studies, Raman spectroscopy, and X-ray absorption spectroscopy (XAS) indicate that the deposition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0725d42c1d7621b0c35ad5a996d7c14d
https://doi.org/10.1021/jacs.5b05945
https://doi.org/10.1021/jacs.5b05945
Autor:
Manos Mavrikakis, Sha Li, Ronald Carrasquillo-Flores, James A. Dumesic, Suyash Singh, Ana C. Alba-Rubio
Publikováno v:
AIChE Journal. 60:1303-1319
A combined theoretical and experimental approach is presented that uses a comprehensive mean-field microkinetic model, reaction kinetics experiments, and scanning transmission electron microscopy imaging to unravel the reaction mechanism and provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14cfdba37e0f7d76f0023a618a6551b4
https://doi.org/10.1002/aic.14401
https://doi.org/10.1002/aic.14401
Autor:
Ronald Carrasquillo-Flores, Konstanze Hahn, Manos Mavrikakis, Jean Marcel R. Gallo, James A. Dumesic
Publikováno v:
ChemCatChem. 5:3690-3699
Periodic, self-consistent density functional theory calculations (DFT-GGA-PW91) on Pt(111) and Pt3Re(111) surfaces, reaction kinetics measurements, and microkinetic modeling are employed to study the mechanism of the water–gas shift (WGS) reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4589cd7eb13bf65218f4fc655398ebda
https://doi.org/10.1002/cctc.201300365
https://doi.org/10.1002/cctc.201300365
Publikováno v:
ACS Catalysis. 3:993-997
Driven by mechanical forces, the acid-catalyzed depolymerization of solid biomass completely overcomes the problems posed by the recalcitrance of lignocellulose. The solid-state reaction leads to water-soluble oligosaccharides, which display higher r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e6430e4c137ad210d0c1462e1ae8dd4
https://doi.org/10.1021/cs4001333
https://doi.org/10.1021/cs4001333