Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ronald C. Tomlinson"'
Autor:
Neil P. Grimster, Lakshmaiah Gingipalli, Bernard Barlaam, Qibin Su, XiaoLan Zheng, David Watson, Haixia Wang, Iain Simpson, Andy Pike, Amber Balazs, Scott Boiko, Timothy P. Ikeda, Anna C. Impastato, Natalie H. Jones, Sameer Kawatkar, Paul Kemmitt, Scott Lamont, Joe Patel, Jon Read, Ujjal Sarkar, Li Sha, Ronald C. Tomlinson, Haiyun Wang, David M. Wilson, Troy E. Zehnder, Lianghe Wang, Peng Wang, Frederick W. Goldberg, Wenlin Shao, Stephen Fawell, Hannah Dry, James E. Dowling, Scott D. Edmondson
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 30:127433
Spleen tyrosine kinase (SYK) is a non-receptor cytosolic kinase. Due to its pivotal role in B cell receptor and Fc-receptor signaling, inhibition of SYK has been targeted in a variety of disease areas. Herein, we report the optimization of a series o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300ccf0156daf617e8afd1d69c45160f
https://doi.org/10.1016/j.bmcl.2020.127433
https://doi.org/10.1016/j.bmcl.2020.127433
Autor:
Bruce M. Baron, David A. Demeter, Ronald C. Tomlinson, Ian A. McDonald, Salituro Francesco G, Herschel J. R. Weintraub
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 1:455-460
The syntheses and molecular modeling of several 3-acylamino-2-carboxyindole antagonists of the glycine binding site associated with the NMDA receptor complex is described. Tertiary amide 8 is a potent antagonist; this result is rationalized by a pref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2652ec6b831550d1c83cb46e6dafab90
https://doi.org/10.1016/s0960-894x(01)81105-7
https://doi.org/10.1016/s0960-894x(01)81105-7
Conference
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