Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ronald C. Herman"'
Autor:
Mariola Ilnicka, John C. Hunter, Douglas Kenneth Rabert, Susan L. Naylor, Ronald C. Herman, Lakshmi Sangameswaran, Rena Obernolte, Richard M. Eglen, Bruce D. Koch
Publikováno v:
Pain. 78:107-114
Neuropathic pain may be produced, at least in part, by the increased activity of primary afferent neurons. Studies have suggested that an accumulation of voltage-gated sodium channels at the site of peripheral nerve injury is a primary precursory eve
Autor:
Elda Tzoumaka, Richard M. Eglen, Douglas Kenneth Rabert, Hardy W. Chan, Sanja D. Novakovic, Stephen Gregory Delgado, Ronald C. Herman, Gregory R. Stewart, Ping Sze, Linda Marie Fish, Mariola Ilnicka, Kimberley Wong, Lyn B. Jakeman, Bruce D. Koch, Lakshmi Sangameswaran, John C. Hunter
Publikováno v:
Journal of Biological Chemistry. 272:14805-14809
Dorsal root ganglion neurons express a wide repertoire of sodium channels with different properties. Here, we report the cloning from rat, dorsal root ganglia (DRG), cellular expression, and functional analysis of a novel tetrodotoxin-sensitive perip
Autor:
Zhang Li, Ping Sze, Douglas W. Bonhaus, John C. Hunter, Dana N. Loury, Zhen Cao, Li-Feng Chang, Ronald C. Herman, Christine M Brown
Publikováno v:
Neuropharmacology. 35:605-613
Mammalian brain sodium channels consist of an α subunit and two smaller β subunits. The role of the β1 subunit in modulating ligand interactions at these channels was examined using a cell line stably expressing human β1 and rat brain IIA α subu
Publikováno v:
Virus Genes. 7:171-186
We report the construction of a deletion mutant (del22Z) that is unable to synthesize any detectable messenger RNA or protein products from the herpes simplex virus type 1 (HSV-1) immediate early ICP22 gene upon infection. The del22Z deletion mutant
Publikováno v:
Antiviral Research. 17:145-156
The role of herpes simplex virus type 1 (HSV-1)-encoded ribonucleotide reductase (RR) has been investigated in mice and guinea pigs using a mutant from which 90% of the large subunit of the enzyme was deleted. The RR mutant was extremely impaired in
Autor:
Lars Haarr, Patricia Y. Jun, Ronald C. Herman, Lisa Strelow, Truls Eide, David A. Leib, Howard S. Marsden
Publikováno v:
The Journal of general virology. 79
The UL4 gene of herpes simplex virus type 1 is predicted to encode a 21.5 kDa protein of 199 amino acids. Although UL4 is dispensable for growth in cell culture, its function is not known. In the present study, the promoter of UL4 was examined and fo
Autor:
Gregory R. Stewart, Lyn B. Jakeman, Lakshmi Sangameswaran, Stephen Gregory Delgado, Ping Sze, Bruce D. Koch, John C. Hunter, Linda Marie Fish, Ronald C. Herman, Richard M. Eglen
Publikováno v:
The Journal of biological chemistry. 271(11)
Small neurons of the dorsal root ganglia (DRG) are known to play an important role in nociceptive mechanisms. These neurons express two types of sodium current, which differ in their inactivation kinetics and sensitivity to tetrodotoxin. Here, we rep
Autor:
Ping Sze, Ronald C. Herman
Publikováno v:
Virus research. 26(2)
Expression from the promoter for the large subunit (ICP6) of the ribonucleotide reductase encoded by herpes simplex virus type 1 (HSV-1) has been examined. Using the lacZ reporter gene fused in-frame with ICP6 regulatory sequences to assay expression
Publikováno v:
Virus Research. 2:345-358
The human B-lymphoblastoid cell line Raji is nonpermissive for infection by vesicular stomatitis virus (VSV). The VSV particles released from Raji cells display a more heterogeneous distribution in equilibrium sucrose density gradients than particles
Publikováno v:
Journal of Virology. 34:550-559
The 5'-terminal nucleotide sequence from positions 50 to 130 of vesicular stomatitis virus RNA was determined indirectly by using a defective interfering particle RNA which contains covalently linked genomic minus and antigenomic plus sense RNAs. The