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pro vyhledávání: '"Ronald C. Bates"'
Autor:
Victor Fedij, Erdman David Thomas, Bryce K. Assink, Ronald C. Bates, Sandra M. Jennings, Traci L. Smith, Timothy L. Stuk, Jennifer A. Lassig, Randy J. Smith
Publikováno v:
Organic Process Research & Development. 7:851-855
The compound (+)-2-(7-chloro-1,8-naphthyridin-2-yl)-3S-(5-methyl-2-oxohexyl)-1-isoindolinone (pagoclone) shows anxiolytic activity due to partial agonism of the benzodiazepine site of the GABAA rec...
Publikováno v:
Journal of Chromatography A. 890:25-36
The separation of proteins using high-performance chromatofocusing with linear or concave pH gradients formed using simple mixtures of buffering species in the elution buffer is investigated experimentally. The separation achieved is comparable to th
Autor:
Douglas D. Frey, Ronald C Bates
Publikováno v:
Journal of Chromatography A. 814:43-54
Chromatofocusing utilizes internally generated, retained pH gradients to focus proteins into narrow chromatographic bands. One of the characteristics of current chromatofocusing methods is that they use expensive polyampholyte buffers containing larg
Summary This chapter briefly describes the various types of packing materials and equipment that can be utilized to isolate impurities from drug substances. It then goes into how to screen for impurity isolation and how to move from the screening pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70becb2c7e694a7a60892d0ce3ee07fc
https://doi.org/10.1016/s0149-6395(03)80012-0
https://doi.org/10.1016/s0149-6395(03)80012-0