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Autor:
Ying Zheng, Katherine H. Shiavoni, Albena T. Dinkova-Kostova, Dale F. Mierke, Tadashi Honda, Y. R. Santosh Laxmi, W. Christian Wigley, Ronald Bumeister, Yanqing Ren, Isaac Trevino, Emilie David, Suqing Zheng, James B. Bliska, Iwao Ojima
Publikováno v:
Journal of Medicinal Chemistry. 55:4837-4846
Novel monocyclic cyanoenones examined to date display unique features regarding chemical reactivity as Michael acceptors and biological potency. Remarkably, in some biological assays, the simple structure is more potent than pentacyclic triterpenoids