Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Ronald B. Gammill"'
Autor:
Cheney Bv, Steve A. Mizsak, Lester A. Dolak, W. Watt, John Tulinsky, Thomas M. Judge, Ronald B. Gammill, Fusen Han
Publikováno v:
The Journal of Organic Chemistry. 64:93-100
Cyclization of (S,S)-alpha-[(1-phenylethyl)amino]-alpha-(2-iodophenyl)acetonitrile with (COCl)(2) in toluene or chlorobenzene afforded the atropisomeric pyrazinone (aS,S) 6-(2-alpha-iodophenyl)-3,5-dichloro-1-(1-phenylethyl)-2(1H)-pyrazinone in 57% y
Publikováno v:
Tetrahedron. 53:11211-11222
An alternative method for the synthesis of 2-amino-5,6-dihydro-4H-pyran-4-ones and 5,6-dihydro-4H-pyran-4-ones is described. This preparation makes use of the condensation of titanium enolates derived from β-hydroxy ketones with phosgene iminium chl
Autor:
Suvit Thaisrivongs, Harvey I. Skulnick, Steve R. Turner, Joseph W. Strohbach, Ruben A. Tommasi, Paul D. Johnson, Paul A. Aristoff, Thomas M. Judge, Ronald B. Gammill, Jeanette K. Morris, Karen R. Romines, Robert A. Chrusciel, Roger R. Hinshaw, Kong-Teck Chong, W. Gary Tarpley, Susan M. Poppe, David E. Slade, Janet C. Lynn, Miao-Miao Horng, Paul K. Tomich, Eric P. Seest, Lester A. Dolak, W. Jeffrey Howe, Gina M. Howard, Francis J. Schwende, Lisa N. Toth, Guy E. Padbury, Grace J. Wilson, Lihua Shiou, Gail L. Zipp, Karen F. Wilkinson, Bob D. Rush, Mary J. Ruwart, Kenneth A. Koeplinger, Zhiyang Zhao, Serena Cole, Renee M. Zaya, Thomas J. Kakuk, Musiri N. Janakiraman, Keith D. Watenpaugh
Publikováno v:
Journal of Medicinal Chemistry. 39:4349-4353
Autor:
William Watt, Ronald B. Gammill, Stephen A. Mizsak, Lester A. Dolak, Thomas M. Judge, John Tulinsky
Publikováno v:
Tetrahedron Letters. 36:2017-2020
Cyclization of ( S , S )- α -[(1-phenylethyl)amino]- α -(2-iodophenyl)acetonitrile 3a with (COCl) 2 in toluene or chlorobenzene afforeded the atropisomeric pyrazinone ( aS , S ) 6-(2-α-iodophenyl)-3,5-dichloro-1-(1-phenylethyl)-2(1H)-pyrazinone 7a
Autor:
John Tulinsky, Ronald B. Gammill
Publikováno v:
Current Medicinal Chemistry. 1:226-253
Abstract: The inhibitory neurotransmitter y-aminobutyrate (GA8A) elicits its physiological effects through interactions with two distinct classes of cell surface receptors in the central nervous system. The GA8AA receptor is a member of the superfa
Autor:
Sharon N. Bisaha, Alice H. Lin, Donn G. Wishka, W R Humphrey, T M Judge, C S Jacob, N L Olds, Joel Morris, Ronald B. Gammill, A L Wiltse
Publikováno v:
Journal of Medicinal Chemistry. 36:2026-2032
The synthesis and biological evaluation of a series of antiplatelet 2-morpholinylchromones has been described. Modification of the C-7 phenylmethoxy group of 8-methyl-7-(phenylmethoxy)-2-(4-morpholinyl)-4H-1-benzopyran-4-one (2) has led to the discov
Autor:
Stephen A. Mizsak, Sharon A. Nash, Larry T. Bell, Ronald B. Gammill, Terrence A. Scahill, Denis M. Sobieray, William Watt
Publikováno v:
ChemInform. 22
A unique mode of metal hydride reduction of unsaturated ketones is described which proceeds with a high degree of regio- and stereocontrol.
Publikováno v:
ChemInform. 23
Publikováno v:
ChemInform. 23
Autor:
Lester A. Dolak, Thomas M. Judge, Ronald B. Gammill, Stephen A. Mizsak, William Watt, John Tulinsky
Publikováno v:
ChemInform. 26
Cyclization of ( S , S )- α -[(1-phenylethyl)amino]- α -(2-iodophenyl)acetonitrile 3a with (COCl) 2 in toluene or chlorobenzene afforeded the atropisomeric pyrazinone ( aS , S ) 6-(2-α-iodophenyl)-3,5-dichloro-1-(1-phenylethyl)-2(1H)-pyrazinone 7a