Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ronald B Myers"'
Autor:
Samuel Lee, Soo Min Kim, James Dotimas, Letitia Li, Edward P Feener, Stephan Baldus, Ronald B Myers, William A Chutkow, Parth Patwari, Jun Yoshioka, Richard T Lee
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 6, Pp 732-743 (2014)
Abstract The endoplasmic reticulum (ER) is responsible for protein folding, modification, and trafficking. Accumulation of unfolded or misfolded proteins represents the condition of ER stress and triggers the unfolded protein response (UPR), a key me
Externí odkaz:
https://doaj.org/article/1d23193913504da3ae2ee569b134a0fe
Autor:
James R Dotimas, Austin W Lee, Angela B Schmider, Shannon H Carroll, Anu Shah, Julide Bilen, Kayla R Elliott, Ronald B Myers, Roy J Soberman, Jun Yoshioka, Richard T Lee
Publikováno v:
eLife, Vol 5 (2016)
Metabolic studies suggest that the absorptive capacity of the small intestine for fructose is limited, though the molecular mechanisms controlling this process remain unknown. Here we demonstrate that thioredoxin-interacting protein (Txnip), which re
Externí odkaz:
https://doaj.org/article/feec9b69db374cbf80e078c2f6484bd5
Autor:
Ronald B Myers, Max Tan, Samuel Lee, Jun Yoshioka, Parth Patwari, Bing F. Wang, Gregory M Fomovsky
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H1748-H1759
Although the precise pathogenesis of diabetic cardiac damage remains unclear, potential mechanisms include increased oxidative stress, autonomic nervous dysfunction, and altered cardiac metabolism. Thioredoxin-interacting protein (Txnip) was initiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd55f34fc156a259b9b2d31d2d11d27
https://doi.org/10.1152/ajpheart.00051.2016
https://doi.org/10.1152/ajpheart.00051.2016
Autor:
Richard T. Lee, Soo Min Kim, James R Dotimas, Stephan Baldus, Samuel Lee, Letitia Li, Parth Patwari, William A. Chutkow, Edward P. Feener, Ronald B Myers, Jun Yoshioka
Publikováno v:
EMBO Molecular Medicine
The endoplasmic reticulum (ER) is responsible for protein folding, modification, and trafficking. Accumulation of unfolded or misfolded proteins represents the condition of ER stress and triggers the unfolded protein response (UPR), a key mechanism l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::706049c18bbb4c45987db84a9d9a7921
http://europepmc.org/articles/PMC4203352
http://europepmc.org/articles/PMC4203352
Autor:
Jun Yoshioka, Ronald B Myers
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 308:H967-H969
despite remarkable improvements in cardiac mortality rates during the past decades ([4][1]), poor quality of life remains a major concern for patients with heart failure. One of the determinants of quality of life is exercise tolerance ([6][2]). Limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::640174912f1ec59e78e3d67f23b1efb6
https://doi.org/10.1152/ajpheart.00169.2015
https://doi.org/10.1152/ajpheart.00169.2015
Autor:
Kayla R Elliott, Richard T. Lee, Jun Yoshioka, Anu Shah, Austin Lee, Ronald B Myers, Julide Bilen, James R Dotimas, Roy J. Soberman, Angela B. Schmider, Shannon H. Carroll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ed78443f5bb88295f2b1c0f08ad1974
https://doi.org/10.7554/elife.18313.024
https://doi.org/10.7554/elife.18313.024
Publikováno v:
Circulation Research. 119
A change in basal glucose transport into skeletal muscle, heart, and adipose is a critical feature of insulin resistance and diabetes. Glucose transport is tightly regulated by a protein family of glucose transporters (GLUTs). Thus, defining how card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::094983376a94257dffbe23a1cbbe6c7d
https://doi.org/10.1161/res.119.suppl_1.108
https://doi.org/10.1161/res.119.suppl_1.108
Autor:
Richard T. Lee, Anu Shah, James R Dotimas, Austin Lee, Kayla R Elliott, Jun Yoshioka, Roy J. Soberman, Shannon H. Carroll, Angela B. Schmider, Julide Bilen, Ronald B Myers
Publikováno v:
eLife, Vol 5 (2016)
eLife
eLife
Metabolic studies suggest that the absorptive capacity of the small intestine for fructose is limited, though the molecular mechanisms controlling this process remain unknown. Here we demonstrate that thioredoxin-interacting protein (Txnip), which re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfba87b3340a2b3839a51f61f9ce2fac
https://pubmed.ncbi.nlm.nih.gov/27808273
https://pubmed.ncbi.nlm.nih.gov/27808273
CCN proteins play crucial roles in cell motility, matrix turnover, and proliferation. In particular, CCN5 plays a role in cell motility and proliferation in several cell types; however, no functional binding proteins for CCN5 have been identified. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec714f5547354ebc372056be53fa1682
https://europepmc.org/articles/PMC4063992/
https://europepmc.org/articles/PMC4063992/
CCN proteins play crucial roles in development, angiogenesis, cell motility, matrix turnover, proliferation, and other fundamental cell processes. Early embryonic lethality in CCN5 knockout and over-expressing mice led us to characterize CCN5 distrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111262b8862d4ae7e9ed25323f30baad
https://europepmc.org/articles/PMC3497895/
https://europepmc.org/articles/PMC3497895/