Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Ronald B, Emeson"'
Publikováno v:
Molecular Brain, Vol 10, Iss 1, Pp 1-9 (2017)
Abstract A-to-I RNA editing is an important process for generating molecular diversity in the brain through modification of transcripts encoding several proteins important for neuronal signaling. We investigated the relationships between the extent o
Externí odkaz:
https://doaj.org/article/3c31988ffac5400fba1458f4ce904277
Autor:
Zhaiyi Zhang, Manli Shen, Paul J Gresch, Masoud Ghamari‐Langroudi, Alexander G Rabchevsky, Ronald B Emeson, Stefan Stamm
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 8, Pp 878-894 (2016)
Abstract The serotonin 2C receptor regulates food uptake, and its activity is regulated by alternative pre‐mRNA splicing. Alternative exon skipping is predicted to generate a truncated receptor protein isoform, whose existence was confirmed with a
Externí odkaz:
https://doaj.org/article/a6f72dfd59c54ff8a4ad50a869f07a9b
Autor:
Chengwen Zhou, Li Ding, M. Elizabeth Deel, Elizabeth A. Ferrick, Ronald B. Emeson, Martin J. Gallagher
Publikováno v:
Neurobiology of Disease, Vol 73, Iss , Pp 407-417 (2015)
We previously demonstrated that heterozygous deletion of Gabra1, the mouse homolog of the human absence epilepsy gene that encodes the GABAA receptor (GABAAR) α1 subunit, causes absence seizures. We showed that cortex partially compensates for this
Externí odkaz:
https://doaj.org/article/00aabe1dac3a40628d3536bf9e59d6b5
Autor:
Alexander Bartelt, Anke Jeschke, Brigitte Müller, Isabella Gaziano, Michelle Morales, Timur Yorgan, Timo Heckt, Markus Heine, Robert F Gagel, Ronald B Emeson, Michael Amling, Andreas Niemeier, Jörg Heeren, Thorsten Schinke, Johannes Keller
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0180547 (2017)
Key metabolic hormones, such as insulin, leptin, and adiponectin, have been studied extensively in obesity, however the pathophysiologic relevance of the calcitonin family of peptides remains unclear. This family includes calcitonin (CT), its precurs
Externí odkaz:
https://doaj.org/article/ce6530ae24dc4ee8950d1f77f22b9c2e
Publikováno v:
J Neurochem
Calcium-dependent activator protein for secretion 1 (CAPS1) is a SNARE accessory protein that facilitates formation of the SNARE complex to enable neurotransmitter release. Messenger RNAs encoding CAPS1 are subject to a site-specific adenosine-to-ino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c55863d462a82a64196ee0abf299f00
https://doi.org/10.1111/jnc.15372
https://doi.org/10.1111/jnc.15372
Autor:
Theodore M Hill, Ronald B. Emeson, Peter A. Beal, Vandana M Gaded, Turnee N Malik, Erin E Doherty
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 49, iss 7
Nucleic acids research, vol 49, iss 7
The hydrolytic deamination of adenosine-to-inosine (A-to-I) by RNA editing is a widespread post-transcriptional modification catalyzed by the adenosine deaminase acting on RNA (ADAR) family of proteins. ADAR-mediated RNA editing modulates cellular pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d828d256bb0c7074181004ca34bc18
http://europepmc.org/articles/PMC8053123
http://europepmc.org/articles/PMC8053123
Autor:
Douglas G. McMahon, Chad R. Jackson, Pat Levitt, Justin K. Siemann, Turnee N Malik, Noah H. Green, Ronald B. Emeson, Piper Williams
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Photoperiod or the duration of daylight has been implicated as a risk factor in the development of mood disorders. The dopamine and serotonin systems are impacted by photoperiod and are consistently associated with affective disorders. Hence, we eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8811b14c35614c90713542a05c239d4c
http://link.springer.com/article/10.1038/s41598-020-72263-5
http://link.springer.com/article/10.1038/s41598-020-72263-5
Autor:
Richard T. O'Neil, Ronald B. Emeson
Publikováno v:
Neurobiology of Disease, Vol 45, Iss 1, Pp 8-13 (2012)
Initially identified as an RNA modification in the anticodon loop of tRNAs from animal, plant and eubacterial origin, the deamination of adenosine-to-inosine by RNA editing has become increasingly recognized as an important RNA processing event to ge
Externí odkaz:
https://doaj.org/article/19ad1862d69046be8ea9991038ee77b8
Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader–Willi syndrome
Autor:
Michael V. Morabito, Atheir I. Abbas, Jennifer L. Hood, Robert A. Kesterson, Michelle M. Jacobs, David S. Kump, David L. Hachey, Bryan L. Roth, Ronald B. Emeson
Publikováno v:
Neurobiology of Disease, Vol 39, Iss 2, Pp 169-180 (2010)
RNA transcripts encoding the 2C-subtype of serotonin (5HT2C) receptor undergo up to five adenosine-to-inosine editing events to encode twenty-four protein isoforms. To examine the effects of altered 5HT2C editing in vivo, we generated mutant mice sol
Externí odkaz:
https://doaj.org/article/a3f569d7de2e4b4798f5df34f527274b
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071607862
Methods in Molecular Biology ISBN: 9781071607862
The conversion of adenosine to inosine (A to I) by RNA editing represents a common posttranscriptional mechanism for diversification of both the transcriptome and proteome, and is a part of the cellular response for innate immune tolerance. Due to it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5084ce9430d3da0d8a48489207e5c8db
https://europepmc.org/articles/PMC8208106/
https://europepmc.org/articles/PMC8208106/
