Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ronald A. Coss"'
Autor:
Ronald A. Coss
Publikováno v:
International Journal of Hyperthermia. 21:695-701
Cancer treatments that incorporate thermal therapy and some systemic therapies induce the production of heat shock or stress proteins. The induced heat shock proteins could lessen the effect of the therapy by inhibiting apoptotic signaling and by act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14a8e5c826ce0b67b0594f6e36c271f1
https://doi.org/10.1080/02656730500331918
https://doi.org/10.1080/02656730500331918
Autor:
Phyllis R. Wachsberger, Miriam L. Wahl, David Berd, Dennis B. Leeper, C. W. Storck, J Reilly, Ronald A. Coss
Publikováno v:
International Journal of Hyperthermia. 20:93-106
Two human melanoma cell lines, SK-Mel-28 and DB-1, were used for in vitro studies of the mechanisms underlying heat resistance of human tumour cells adapted to growth in acidic environments. Adaptation to growth at low pH was characterized by resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6871cb73dbb254017fceb2b665e8b1
https://doi.org/10.1080/02656730310001605519
https://doi.org/10.1080/02656730310001605519
Autor:
Phyllis R. Wachsberger, J.-S. Han, Miriam L. Wahl, C. W. Storck, Ronald A. Coss, David Berd, Dennis B. Leeper
Publikováno v:
International Journal of Hyperthermia. 18:404-415
Acute acidification is being investigated as a strategy to sensitize human melanoma to 42 degrees C hyperthermia. The present study was conducted to determine the effect of hyperthermia and acute extracellular acidification on the nuclear associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c329365aa5265bc7c098d542820e55
https://doi.org/10.1080/02656730210129745
https://doi.org/10.1080/02656730210129745
Publikováno v:
International Journal of Hyperthermia. 18:216-232
CHO cells are normally sensitized to hyperthermia by acidic pH. However, CHO cells adapted to growth in pH 6.7 medium become less sensitive to heat killing at the reduced pH. The adapted cells maintain their ability to develop thermotolerance at pH 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5170bc59949c7999ddaa6d236f322d9c
https://doi.org/10.1080/02656730110119189
https://doi.org/10.1080/02656730110119189
Publikováno v:
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 30(1)
This study tested the ability of lonidamine (LND), a clinically applicable inhibitor of monocarboxylate transporters (MCT), to thermally sensitise human melanoma cells cultured at a tumour-like extracellular pH (pHe) 6.7.Human melanoma DB-1 cells cul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78689f1d7ff16350f95d9fceda6e1876
https://pubmed.ncbi.nlm.nih.gov/24295212
https://pubmed.ncbi.nlm.nih.gov/24295212
Publikováno v:
International Journal of Hyperthermia. 14:227-232
Cells which have been adapted to growth at low extracellular pH (pHe) typically develop both an upregulation of steady state intracellular pH (pHi) and an ability to develop thermotolerance to 42 degrees C hyperthermia. These properties were acquired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165400f13ad9fdb0f4f72f25558de4fa
https://doi.org/10.3109/02656739809018227
https://doi.org/10.3109/02656739809018227
Publikováno v:
Journal of Cellular Physiology. 173:397-405
Intracellular pH (pHi) homeostasis is crucial to cell survival. Cells that are chronically exposed to a low pH environment must adapt their hydrogen ion extrusion mechanisms to maintain their pHi in the physiologic range. An important component of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ba3f83c16d14891fb6c6a41b4c0befd
https://doi.org/10.1002/(sici)1097-4652(199712)173:3<397::aid-jcp12>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199712)173:3<397::aid-jcp12>3.0.co
Publikováno v:
Journal of Cellular Physiology. 166:438-445
As an in vitro model for the low extracellular pH (pHe) which has frequently been observed in tumors, cell lines have been grown in a low-pH medium in order to allow cell adaptation to that milieu. Two Chinese hamster cell lines [Chinese hamster ovar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd8492bd73b639a350d57a0a3281df57
https://doi.org/10.1002/(sici)1097-4652(199602)166:2<438::aid-jcp22>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199602)166:2<438::aid-jcp22>3.0.co
Publikováno v:
International Journal of Hyperthermia. 12:173-196
(1996). The effects of hyperthermia on the cytoskeleton: a review. International Journal of Hyperthermia: Vol. 12, No. 2, pp. 173-196.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de5d7152cbe067eb94fc4622a174af2e
https://doi.org/10.3109/02656739609022507
https://doi.org/10.3109/02656739609022507
Publikováno v:
International Journal of Hyperthermia. 11:389-396
Two independent laboratories have demonstrated that suspension-grown, Chinese hamster ovary (CHO) cells can be made thermotolerant, frozen and subsequently thawed such that they still express thermotolerance. Thermotolerance was determined as the abi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6873076b79a13bd0812c4d837d5d50
https://doi.org/10.3109/02656739509022474
https://doi.org/10.3109/02656739509022474