Serum lipids in adults with late age-related macular degeneration: a case-control study

Autor: Richard D. Semba, Ruin Moaddel, Mary Frances Cotch, Fridbert Jonasson, Gudny Eiriksdottir, Tamara B. Harris, Lenore J. Launer, Kai Sun, Ronald Klein, Debra A. Schaumberg, Pálmi Jónsson, Vilmundur Gudnason, Luigi Ferrucci

Publikováno v: Lipids in Health and Disease, Vol 18, Iss 1, Pp 1-4 (2019)

Abstract Background Lipids are implicated in the pathogenesis of age-related macular degeneration (AMD). The relationship between systemic lipids and AMD has not been well characterized. The objective was to investigate the relationship between serum

Externí odkaz: https://doaj.org/article/4019348a7b8f40afbb74cf78e97e46d7

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

Autor: Emily R. Holzinger, Shefali S. Verma, Carrie B. Moore, Molly Hall, Rishika De, Diane Gilbert-Diamond, Matthew B. Lanktree, Nathan Pankratz, Antoinette Amuzu, Amber Burt, Caroline Dale, Scott Dudek, Clement E. Furlong, Tom R. Gaunt, Daniel Seung Kim, Helene Riess, Suthesh Sivapalaratnam, Vinicius Tragante, Erik P.A. van Iperen, Ariel Brautbar, David S. Carrell, David R. Crosslin, Gail P. Jarvik, Helena Kuivaniemi, Iftikhar J. Kullo, Eric B. Larson, Laura J. Rasmussen-Torvik, Gerard Tromp, Jens Baumert, Karen J. Cruickshanks, Martin Farrall, Aroon D. Hingorani, G. K. Hovingh, Marcus E. Kleber, Barbara E. Klein, Ronald Klein, Wolfgang Koenig, Leslie A. Lange, Winfried Mӓrz, Kari E. North, N. Charlotte Onland-Moret, Alex P. Reiner, Philippa J. Talmud, Yvonne T. van der Schouw, James G. Wilson, Mika Kivimaki, Meena Kumari, Jason H. Moore, Fotios Drenos, Folkert W. Asselbergs, Brendan J. Keating, Marylyn D. Ritchie

Publikováno v: BioData Mining, Vol 10, Iss 1, Pp 1-20 (2017)

Abstract Background The genetic etiology of human lipid quantitative traits is not fully elucidated, and interactions between variants may play a role. We performed a gene-centric interaction study for four different lipid traits: low-density lipopro

Externí odkaz: https://doaj.org/article/e425535da8ac4698843693a6461d84e0

Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error

Autor: Qiao Fan, Virginie J. M. Verhoeven, Robert Wojciechowski, Veluchamy A. Barathi, Pirro G. Hysi, Jeremy A. Guggenheim, René Höhn, Veronique Vitart, Anthony P. Khawaja, Kenji Yamashiro, S Mohsen Hosseini, Terho Lehtimäki, Yi Lu, Toomas Haller, Jing Xie, Cécile Delcourt, Mario Pirastu, Juho Wedenoja, Puya Gharahkhani, Cristina Venturini, Masahiro Miyake, Alex W. Hewitt, Xiaobo Guo, Johanna Mazur, Jenifer E. Huffman, Katie M. Williams, Ozren Polasek, Harry Campbell, Igor Rudan, Zoran Vatavuk, James F. Wilson, Peter K. Joshi, George McMahon, Beate St Pourcain, David M. Evans, Claire L. Simpson, Tae-Hwi Schwantes-An, Robert P. Igo, Alireza Mirshahi, Audrey Cougnard-Gregoire, Céline Bellenguez, Maria Blettner, Olli Raitakari, Mika Kähönen, Ilkka Seppälä, Tanja Zeller, Thomas Meitinger, Janina S. Ried, Christian Gieger, Laura Portas, Elisabeth M. van Leeuwen, Najaf Amin, André G. Uitterlinden, Fernando Rivadeneira, Albert Hofman, Johannes R. Vingerling, Ya Xing Wang, Xu Wang, Eileen Tai-Hui Boh, M. Kamran Ikram, Charumathi Sabanayagam, Preeti Gupta, Vincent Tan, Lei Zhou, Candice E. H. Ho, Wan’e Lim, Roger W. Beuerman, Rosalynn Siantar, E-Shyong Tai, Eranga Vithana, Evelin Mihailov, Chiea-Chuen Khor, Caroline Hayward, Robert N. Luben, Paul J. Foster, Barbara E. K. Klein, Ronald Klein, Hoi-Suen Wong, Paul Mitchell, Andres Metspalu, Tin Aung, Terri L. Young, Mingguang He, Olavi Pärssinen, Cornelia M. van Duijn, Jie Jin Wang, Cathy Williams, Jost B. Jonas, Yik-Ying Teo, David A. Mackey, Konrad Oexle, Nagahisa Yoshimura, Andrew D. Paterson, Norbert Pfeiffer, Tien-Yin Wong, Paul N. Baird, Dwight Stambolian, Joan E. Bailey Wilson, Ching-Yu Cheng, Christopher J. Hammond, Caroline C. W. Klaver, Seang-Mei Saw, Consortium for Refractive Error and Myopia (CREAM)

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)

This report by the Consortium for Refractive Error and Myopia uses gene-environment-wide interaction study (GEWIS) to identify genetic loci that affect environmental influence in myopia development, and identifies ethnic specific genetic loci that at

Externí odkaz: https://doaj.org/article/b0563139c510416e9a4da61510e1f5d4

Age-related macular degeneration and progression of coronary artery calcium: The Multi-Ethnic Study of Atherosclerosis.

Autor: Antonio B Fernandez, Kevin D Ballard, Tien Y Wong, Mengye Guo, Robyn L McClelland, Gregory Burke, Mary Frances Cotch, Barbara Klein, Matthew Allison, Ronald Klein

Publikováno v: PLoS ONE, Vol 13, Iss 7, p e0201000 (2018)

BACKGROUND:Age-related macular degeneration (AMD) shares many similarities with cardiovascular disease (CVD) pathophysiology. We sought to determine the relationship of AMD to the progression of coronary artery calcium (CAC) using data from the Multi

Externí odkaz: https://doaj.org/article/3589f0803dae4bc2a3024a7897239bda

Relation between Retinopathy and Progression of Coronary Artery Calcium in Individuals with Versus Without Diabetes Mellitus (From the Multi–Ethnic Study of Atherosclerosis)

Autor: Eli Ipp, Ronald S. Swerdloff, Joel D. Kaufman, Mary Frances Cotch, Ronald Klein, Christina Wang, Bahram Khazai, Barbara E.K. Klein, Robert C. Hendel, Matthew J. Budoff, Claire Park, Mengye Guo, Prasanth Surampudi, Fatemeh Adabifirouzjaei, Tien Yin Wong

Publikováno v: The American Journal of Cardiology. 149:1-8

Retinopathy is a microvascular complication of diabetes mellitus (DM); however, it is also increasingly recognized in persons without DM. The microvascular diseases may play a prominent role in coronary heart disease (CHD) development in individuals

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4572331af85e4e027f53b686402e2ab
https://doi.org/10.1016/j.amjcard.2021.03.026