Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Ronald, Herbst"'
Autor:
Ronald Herbst, Anthony Rodriguez, Kei Yasuda, Philipp Steiner, Liyang Diao, Jianwen Feng, Matthew Iovino, Sara Lewandowski, Dan Felitsky, Ben Keller, Ona Miller, Alyssa Quigley, Jan Pinkas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/d58746e935aa484e91284e907bc0b59c
Autor:
Saba Nayar, Elena Pontarini, Joana Campos, Onorina Berardicurti, Charlotte G. Smith, Saba Asam, David H. Gardner, Serena Colafrancesco, Davide Lucchesi, Rachel Coleby, Ming-May Chung, Valentina Iannizzotto, Kelly Hunter, Simon J. Bowman, Gianluca Carlesso, Ronald Herbst, Helen M. McGettrick, Jeff Browning, Christopher D. Buckley, Benjamin A. Fisher, Michele Bombardieri, Francesca Barone
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
The study suggests a link between ICOS-ICOSL signaling and LTa3 induction on T cells. LTa3 subsequently activates fibroblasts in the salivary gland, leading to formation of tertiary lymphoid tissues (TLS).
Externí odkaz:
https://doaj.org/article/d98526377cb948829a419d58788242d6
Autor:
Diane Damotte, Sarah Warren, Jennifer Arrondeau, Pascaline Boudou-Rouquette, Audrey Mansuet-Lupo, Jérôme Biton, Hanane Ouakrim, Marco Alifano, Claire Gervais, Audrey Bellesoeur, Nora Kramkimel, Camille Tlemsani, Barbara Burroni, Angéline Duche, Franck Letourneur, Han Si, Rebecca Halpin, Todd Creasy, Ronald Herbst, Xing Ren, Pascale Morel, Alessandra Cesano, François Goldwasser, Karen Leroy
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-10 (2019)
Abstract Background The 18-gene tumor inflammation signature (TIS) is a clinical research assay that enriches for clinical benefit to immune checkpoint blockade. We evaluated its ability to predict clinical benefit of immunotherapy in cancer patients
Externí odkaz:
https://doaj.org/article/b75c5fd83d2d4639a48bed140c36dd2f
Autor:
Stefanie R. Mullins, John P. Vasilakos, Katharina Deschler, Iwen Grigsby, Pete Gillis, Julius John, Matthew J. Elder, John Swales, Elina Timosenko, Zachary Cooper, Simon J. Dovedi, Andrew J. Leishman, Nadia Luheshi, James Elvecrog, Ashenafi Tilahun, Richard Goodwin, Ronald Herbst, Mark A. Tomai, Robert W. Wilkinson
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract Background Immune checkpoint blockade (ICB) promotes adaptive immunity and tumor regression in some cancer patients. However, in patients with immunologically “cold” tumors, tumor-resident innate immune cell activation may be required to
Externí odkaz:
https://doaj.org/article/664a845e229648008b22d687ebf6b261
Autor:
Inbar Amit, Natalie Levitin, Meital Gadrich, May Ben-Mayor, Timothy Wyant, Reut Barak, Liron Danielpur, Morya Ifrach, Itzhak Meir, Olga Bluvshtein, Yehezkel Sasson, Sharon Fischman, Guy Nimrod, Michael Zhenin, Yair Fastman, James Vasselli, Aron Knickerbocker, Ronald Herbst, Yanay Ofran
Publikováno v:
Journal of Cancer Immunology. 5:29-39
Stimulating effector T-cells (Teffs) without inducing regulatory T-cells (Tregs) has been the primary goal of IL-2-based therapies for cancer. Recently, modified IL-2 designed for differential T-cell expansion for the treatment of cancer has failed i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fedc255e327bd5cddb164889031469e
https://doi.org/10.33696/cancerimmunol.5.074
https://doi.org/10.33696/cancerimmunol.5.074
Autor:
Reena Varkey, Qun Du, Jodi L Karnell, Xiaodong Xiao, Kerry A Casey, Rob Woods, Kim Rosenthal, Susan Wilson, William F Dall'Acqua, Herren Wu, Ronald Herbst, Rachel Ettinger, Melissa Damschroder
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0211236 (2019)
Interleukin-21 (IL-21), a member of the common cytokine receptor γ chain (γc) family, is secreted by CD4+ T cells and natural killer T cells and induces effector function through interactions with the IL-21 receptor (IL-21R)/γc complex expressed o
Externí odkaz:
https://doaj.org/article/e7e6a5a71ae44ef09369d6a607a0b924
Autor:
Gianluca Carlesso, Darren J. Schofield, Ronald Herbst, Geetha K. Bhat, Jeffrey M. Riggs, Yvonne Puplampu-Dove, Zenon Zenonos, Gareth Browne, Andrew Garcia, Tamer I. Mahmoud, Hormas Ghadially, Des C. Jones, Taeil Kim, Madhu Ramaswamy
Supplementary Table 1Suppl. Table 1 related to materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c867539694432660b7dd69219ed965
https://doi.org/10.1158/2326-6066.22544859.v1
https://doi.org/10.1158/2326-6066.22544859.v1
Autor:
Gianluca Carlesso, Darren J. Schofield, Ronald Herbst, Geetha K. Bhat, Jeffrey M. Riggs, Yvonne Puplampu-Dove, Zenon Zenonos, Gareth Browne, Andrew Garcia, Tamer I. Mahmoud, Hormas Ghadially, Des C. Jones, Taeil Kim, Madhu Ramaswamy
Supplementary Figures S1-S7Supplementary Figures S1-S7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10cee7b46fd70653a2fd06bbbb1e9efe
https://doi.org/10.1158/2326-6066.22544862.v1
https://doi.org/10.1158/2326-6066.22544862.v1
Autor:
Gianluca Carlesso, Darren J. Schofield, Ronald Herbst, Geetha K. Bhat, Jeffrey M. Riggs, Yvonne Puplampu-Dove, Zenon Zenonos, Gareth Browne, Andrew Garcia, Tamer I. Mahmoud, Hormas Ghadially, Des C. Jones, Taeil Kim, Madhu Ramaswamy
Checkpoint blockade therapies targeting PD-1/PD-L1 and CTLA-4 are clinically successful but also evoke adverse events due to systemic T-cell activation. We engineered a bispecific, mAb targeting CD28 homolog (CD28H), a newly identified B7 family rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ec9ec374bbda9dffe535a040c2c2b71
https://doi.org/10.1158/2326-6066.c.6550767.v1
https://doi.org/10.1158/2326-6066.c.6550767.v1
Autor:
Michael D. Oberst, Maria Libera Ascierto, Phillip A. Dennis, J. Carl Barrett, Melanie M. Frigault, Rajiv Raja, Shaad E. Abdullah, Ashok Gupta, Ronald Herbst, Ricardo J. Miragaia, Theresa A. Proia, Ina Bisha, Matthew Griffin, John Meekin, Philip Martin, Stephen Blackmore, Kathy Mulgrew, Raymond Rothstein, Rebecca Halpin, Yashaswi Shrestha, Melissa de los Reyes, Maria Jure-Kunkel, Nathan Standifer, Song Wu, Nabendu Pore
Marker genes for the monocyte-macrophage-DC subpopulations identified in Supplementary Figure 5H. Only genes with adjusted p-value < 0.01 and average log fold-change > 0.3 were included. gene, gene name; p_val, p-value calculated based on Wilcoxon te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318ab2f876a4f6d65d1cc34e89e50b21
https://doi.org/10.1158/2159-8290.22540394
https://doi.org/10.1158/2159-8290.22540394