Zobrazeno 1 - 10
of 345
pro vyhledávání: '"Ronald, Ghossein"'
Publikováno v:
Thyroid. 33:586-592
Autor:
Robert Michael Tuttle, James Fagin, Gerald Minkowitz, Richard Wong, Benjamin Roman, Snehal Patel, Brian Untch, Ian Ganly, Ashok Shaha, Jatin Shah, Duan Li, Ariadne Bach, Jeffrey Girshman, Oscar Lin, Marc Cohen, Jean-Marc Cohen, Jennifer Cracchiolo, Ronald Ghossein, Mona Sabra, Laura Boucai, Stephanie Fish, Luc Morris
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 32(11)
Autor:
Gregory W. Randolph, Julie Ann Sosa, Yangyang Hao, Trevor E. Angell, David C. Shonka, Virginia A. LiVolsi, Paul W. Ladenson, Thomas C. Blevins, Quan-Yang Duh, Ronald Ghossein, Mack Harrell, Kepal Narendra Patel, Michael H. Shanik, S. Thomas Traweek, P. Sean Walsh, Michael W. Yeh, Amr H. Abdelhamid Ahmed, Allen S. Ho, Richard J. Wong, Joshua P. Klopper, Jing Huang, Giulia C. Kennedy, Richard T. Kloos, Peter M. Sadow
Publikováno v:
Thyroid : official journal of the American Thyroid Association, vol 32, iss 9
Background: Cytopathological evaluation of thyroid fine-needle aspiration biopsy (FNAB) specimens can fail to raise preoperative suspicion of medullary thyroid carcinoma (MTC). The Afirma RNA-sequencing MTC classifier identifies MTC among FNA samples
Autor:
Nancy Y. Lee, Nadeem Riaz, Vanessa Wu, Thomas Brinkman, Chiaojung J. Tsai, Wanquing Zhi, James Fetten, Alan Ho, Richard J. Wong, Ronald Ghossein, Michael Tuttle, James Fagin, David G. Pfister, Eric Sherman
Publikováno v:
Thyroid
BACKGROUND: Metastatic anaplastic thyroid cancer (ATC) has a poor prognosis. This pilot study aims to evaluate tremelimumab plus durvalumab with stereotactic body radiotherapy (SBRT) to improve overall survival (OS). METHODS: Eligible patients receiv
Autor:
Martin G. Dalin, Nora Katabi, Marta Persson, Ken-Wing Lee, Vladimir Makarov, Alexis Desrichard, Logan A. Walsh, Lyndsay West, Zaineb Nadeem, Deepa Ramaswami, Jonathan J. Havel, Fengshen Kuo, Kalyani Chadalavada, Gouri J. Nanjangud, Ian Ganly, Nadeem Riaz, Alan L. Ho, Cristina R. Antonescu, Ronald Ghossein, Göran Stenman, Timothy A. Chan, Luc G. T. Morris
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Myoepithelial carcinoma (MECA) is a rare aggressive salivary gland cancer. Here, the authors analyze the genomic landscape of MECA and identify a high prevalence of oncogenic gene fusions, primarily PLAG1 fusions, highlighting TGFBR3-PLAG1 as a poten
Externí odkaz:
https://doaj.org/article/ac5cf5be332f48df922f9b4c8c1e098f
Autor:
Ian Ganly, Timothy A. Chan, Ronald Ghossein, Bin Xu, Eric J. Sherman, James A. Fagin, Rui Qu, Huiyong Zhao, Omer Aras, Gouri J. Nanjangud, Ed Reznik, Vladimir Makarov, Fengshen Kuo, Yongxing Gong, Yiyu Dong
Combination treatment with rapamycin and lenvatinib in PDX model TC1m1. A, Combination treatment resulted in enhanced decrease in CD31 staining endothelial vessels compared to lenvatinib alone or rapamycin alone. B, The average IMVD values of CD31 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dabc040d6ab10bff6dcf98b06241993
https://doi.org/10.1158/1535-7163.22522548
https://doi.org/10.1158/1535-7163.22522548
Autor:
James A. Fagin, Richard P. Koche, Alan L. Ho, Ping Chi, Ronald Ghossein, Samuel Refetoff, Xiao-Hui Liao, Bin Xu, Elisa de Stanchina, Jeffrey A. Knauf, Vincent Reuter, Vera Tiedje, Prasanna P. Tamarapu, Gnana P. Krishnamoorthy, Vatche Tchekmedyian, Jesper L.V. Maag, Luis Javier Leandro-Garcia, Mahesh Saqcena
Mutations of subunits of the SWI/SNF chromatin remodeling complexes occur commonly in cancers of different lineages, including advanced thyroid cancers. Here we show that thyroid-specific loss of Arid1a, Arid2, or Smarcb1 in mouse BRAFV600E-mutant tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::382ef22e35e482b9780190e3e8298305
https://doi.org/10.1158/2159-8290.c.6548987.v1
https://doi.org/10.1158/2159-8290.c.6548987.v1
Autor:
James A. Fagin, Richard P. Koche, Alan L. Ho, Ping Chi, Ronald Ghossein, Samuel Refetoff, Xiao-Hui Liao, Bin Xu, Elisa de Stanchina, Jeffrey A. Knauf, Vincent Reuter, Vera Tiedje, Prasanna P. Tamarapu, Gnana P. Krishnamoorthy, Vatche Tchekmedyian, Jesper L.V. Maag, Luis Javier Leandro-Garcia, Mahesh Saqcena
Schema of redifferentiation trials.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c939179fd156e436e6d2bf042f5547
https://doi.org/10.1158/2159-8290.22539119
https://doi.org/10.1158/2159-8290.22539119
Autor:
Luc G.T. Morris, James A. Fagin, Timothy A. Chan, Alan L. Ho, Eric J. Sherman, Richard J. Wong, Snjezana Dogan, Vladimir Makarov, Neal Patel, Zaineb Nadeem, Cristina Valero, Fengshen Kuo, Catherine Han, Ronald Ghossein, Bin Xu, Brian R. Untch, Mark Lee
Targeted inhibition of BRAF V600E achieves tumor control in a subset of advanced thyroid tumors. Nearly all tumors develop resistance, and some have been observed to subsequently undergo dedifferentiation. The molecular alterations associated with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dff8eee2d1cfea9be68c75d008bf1a6
https://doi.org/10.1158/1541-7786.c.6545222
https://doi.org/10.1158/1541-7786.c.6545222
Autor:
James A. Fagin, Richard P. Koche, Alan L. Ho, Ping Chi, Ronald Ghossein, Samuel Refetoff, Xiao-Hui Liao, Bin Xu, Elisa de Stanchina, Jeffrey A. Knauf, Vincent Reuter, Vera Tiedje, Prasanna P. Tamarapu, Gnana P. Krishnamoorthy, Vatche Tchekmedyian, Jesper L.V. Maag, Luis Javier Leandro-Garcia, Mahesh Saqcena
SWISNF mutations in thyroid cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46c38d9a547736bc17b92ae569ed4fcc
https://doi.org/10.1158/2159-8290.22539092.v1
https://doi.org/10.1158/2159-8290.22539092.v1