Awake prone positioning effectiveness in moderate to severe COVID-19 a randomized controlled trial. [version 2; peer review: 2 approved, 1 approved with reservations]

Autor: Nguyen Thanh Phong, Nguyen Thanh Truong, Du Hong Duc, C Louise Thwaites, Nguyen Thanh Dung, Nguyen Thi My Linh, Lam Minh Yen, Nguyen Le Nhu Tung, Luu Hoai Bao Tran, Ho Bich Hai, Le Thuy Thuy Khanh, Nguyen Thi Diem Trinh, James Anibal, Dang Phuong Thao, Pham Tieu Kieu, Nguyen Thi Phuong Dung, Nguyen Thanh Ngoc, Vo Tan Hoang, Tran Thi Dong Vien, Ronald Geskus, Nguyen Thanh Nguyen, Vo Trieu Ly, Tran Dang Khoa, Cao Thi Cam Van, Le Dinh Van Khoa, Abigail Beane, Guy Glover, David Clifton, Evelyne Kestelyn, Guy E Thwaites, Le Van Tan

Publikováno v: Wellcome Open Research, Vol 9 (2024)

Background Awake prone positioning (APP) may be beneficial in patients with respiratory failure who are not receiving mechanical ventilation. Randomized controlled trials of APP have been performed during peak COVID-19 periods in unvaccinated populat

Externí odkaz: https://doaj.org/article/55fe7fbd03fa4af59b451da624eb1e0d

Dengue viremia kinetics and effects on platelet count and clinical outcomes: An analysis of 2340 patients from Vietnam

Autor: Nguyen Lam Vuong, Nguyen Than Ha Quyen, Nguyen Thi Hanh Tien, Kien Duong Thi Hue, Huynh Thi Le Duyen, Phung Khanh Lam, Dong Thi Hoai Tam, Tran Van Ngoc, Thomas Jaenisch, Cameron P Simmons, Sophie Yacoub, Bridget A Wills, Ronald Geskus

Publikováno v: eLife, Vol 13 (2024)

Background: Viremia is a critical factor in understanding the pathogenesis of dengue infection, but limited data exist on viremia kinetics. This study aimed to investigate the kinetics of viremia and its effects on subsequent platelet count, severe d

Externí odkaz: https://doaj.org/article/71169484fc9143f99ecd04ae600ee09c

Direct Medical Costs of Tetanus, Dengue, and Sepsis Patients in an Intensive Care Unit in Vietnam

Autor: Trinh Manh Hung, Nguyen Van Hao, Lam Minh Yen, Angela McBride, Vu Quoc Dat, H. Rogier van Doorn, Huynh Thi Loan, Nguyen Thanh Phong, Martin J. Llewelyn, Behzad Nadjm, Sophie Yacoub, C. Louise Thwaites, Sayem Ahmed, Nguyen Van Vinh Chau, Hugo C. Turner, The Vietnam ICU Translational Applications Laboratory (VITAL) Investigators, Dang Phuong Thao, Dang Trung Kien, Doan Bui Xuan Thy, Dong Huu Khanh Trinh, Du Hong Duc, Ronald Geskus, Ho Bich Hai, Ho Quang Chanh, Ho Van Hien, Huynh Trung Trieu, Evelyne Kestelyn, Le Dinh Van Khoa, Le Thanh Phuong, Luu Hoai Bao Tran, Luu Phuoc An, Angela Mcbride, Nguyen Lam Vuong, Nguyen Quang Huy, Nguyen Than Ha Quyen, Nguyen Thanh Ngoc, Nguyen Thi Giang, Nguyen Thi Le Thanh, Nguyen Thi Phuong Dung, Nguyen Thi Phuong Thao, Ninh Thi Thanh Van, Phan Nguyen Quoc Khanh, Phung Khanh Lam, Phung Tran Huy Nhat, Guy Thwaites, Tran Minh Duc, Jennifer Ilo Van Nuil, Vu Ngo Thanh Huyen, Cao Thi Tam, Duong Bich Thuy, Ha Thi Hai Duong, Ho Dang Trung Nghia, Le Buu Chau, Le Mau Toan, Le Ngoc Minh Thu, Le Thi Mai Thao, Luong Thi Hue Tai, Nguyen Hoan Phu, Nguyen Quoc Viet, Nguyen Thanh Nguyen, Nguyen Thi Kim Anh, Nguyen Van Thanh Duoc, Pham Kieu Nguyet Oanh, Phan Thi Hong Van, Phan Tu Qui, Phan Vinh Tho, Truong Thi Phuong Thao, Natasha Ali, David Clifton, Mike English, Shadi Ghiasi, Heloise Greeff, Jannis Hagenah, Ping Lu, Jacob McKnight, Chris Paton, Pantelis Georgiou, Bernard Hernandez Perez, Kerri Hill-Cawthorne, Alison Holmes, Stefan Karolcik, Damien Ming, Nicolas Moser, Liane Canas, Alberto Gomez, Hamideh Kerdegari, Marc Modat, Reza Razavi, Linda Denehy, Luigi Pisani, Marcus Schultz

Publikováno v: Frontiers in Public Health, Vol 10 (2022)

BackgroundCritically ill patients often require complex clinical care by highly trained staff within a specialized intensive care unit (ICU) with advanced equipment. There are currently limited data on the costs of critical care in low-and middle-inc

Externí odkaz: https://doaj.org/article/f7077071376a4b659d7c43626ab987a1

Assessing the efficacy and safety of magnesium sulfate for management of autonomic nervous system dysregulation in Vietnamese children with severe hand foot and mouth disease

Autor: Qui Tu Phan, Lam Khanh Phung, Khanh Huu Truong, Trieu Trung Huynh, Giang Thanh Phạm, Bich Ngọc Nguyen, Quyen Thanh Tran, Vuong Ngoc Thien Huynh, Tien Thi My Nguyen, Thoa Phan Kim Le, Nhan Nguyen Thanh Le, Saraswathy Sabanathan, H. Rogier van Doorn, Tan Van Le, Toan Duc Nguyen, Laura Merson, Dung Thi Phuong Nguyen, Ronald Geskus, Hung Thanh Nguyen, Chau Van Vinh Nguyen, Bridget Wills

Publikováno v: BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-12 (2019)

Abstract Background Brainstem encephalitis is a serious complication of hand foot and mouth disease (HFMD) in children. Autonomic nervous system (ANS) dysregulation and hypertension may occur, sometimes progressing to cardiopulmonary failure and deat

Externí odkaz: https://doaj.org/article/35b1366e1057467c9d75b588f81c0c34

A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults

Autor: Nguyen TH Mai, Nicholas Dobbs, Nguyen Hoan Phu, Romain A Colas, Le TP Thao, Nguyen TT Thuong, Ho DT Nghia, Nguyen HH Hanh, Nguyen T Hang, A Dorothee Heemskerk, Jeremy N Day, Lucy Ly, Do DA Thu, Laura Merson, Evelyne Kestelyn, Marcel Wolbers, Ronald Geskus, David Summers, Nguyen VV Chau, Jesmond Dalli, Guy E Thwaites

Publikováno v: eLife, Vol 7 (2018)

Adjunctive dexamethasone reduces mortality from tuberculous meningitis (TBM) but not disability, which is associated with brain infarction. We hypothesised that aspirin prevents TBM-related brain infarction through its anti-thrombotic, anti-inflammat

Externí odkaz: https://doaj.org/article/ca41dbbd23d545c7a32fcb37b31b939e