Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ronald, Flegel"'
Autor:
Ruth E. Winecker, Elia Goffi, George E. Bigelow, Ryan Vandrey, John M. Mitchell, Ronald Flegel, Edward J. Cone, David J. Kuntz, Tory R. Spindle, Dennis J. Sholler
Publikováno v:
J Anal Toxicol
The market for products containing cannabidiol (CBD) is booming globally. However, the pharmacokinetics of CBD in different oral formulations and the impact of CBD use on urine drug testing outcomes for cannabis (e.g., 11-nor-9-carboxy-Δ9-tetrahydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd9a01ff2acb9ac19c9bc2d671d6c980
https://doi.org/10.1093/jat/bkab059
https://doi.org/10.1093/jat/bkab059
Autor:
E Dale Hart, John M. Mitchell, Ronald Flegel, Ruth E. Winecker, Svante Vikingsson, Eugene D Hayes
Publikováno v:
Journal of Analytical Toxicology. 46:573-576
The growing use of cannabidiol (CBD) products by the general public is expected to result in an increase in the prevalence of CBD and the CBD metabolites in drug testing laboratories. CBD converts into tetrahydrocannabinol (THC) under acid conditions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25f8acb5349991b85fb937caf00ab85
https://doi.org/10.1093/jat/bkab046
https://doi.org/10.1093/jat/bkab046
Autor:
Cecilia L Bergeria, Tory R Spindle, Edward J Cone, Dennis Sholler, Elia Goffi, John M Mitchell, Ruth E Winecker, George E Bigelow, Ronald Flegel, Ryan Vandrey
Publikováno v:
J Anal Toxicol
There is limited data on the comparative pharmacokinetics of cannabidiol (CBD) across oral and vaporized formulations. This within-subject, double-blind, double-dummy, placebo-controlled laboratory study analyzed the pharmacokinetic profile of CBD,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029d3fecfe9db7c274c97498f3ff46f6
https://pubmed.ncbi.nlm.nih.gov/35438179
https://pubmed.ncbi.nlm.nih.gov/35438179
Autor:
Ronald Flegel, George E. Bigelow, John M. Mitchell, Evan S. Herrmann, Ryan Vandrey, Tory R. Spindle, Edward J. Cone, Charles LoDico
Publikováno v:
J Anal Toxicol
Oral cannabis products (a.k.a. “edibles”) have increased in popularity in recent years. Most prior controlled pharmacokinetic evaluations of cannabis have focused on smoked cannabis and included males who were frequent cannabis users. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b10bc2569faed54b15b6680e64f96973
https://pubmed.ncbi.nlm.nih.gov/32591782
https://pubmed.ncbi.nlm.nih.gov/32591782
Autor:
Ronald Flegel, Edward J. Cone, Charles LoDico, John M. Mitchell, Ryan Vandrey, Evan S. Herrmann, George E. Bigelow
Publikováno v:
Journal of Analytical Toxicology. 41:83-99
Most research on cannabis pharmacokinetics has evaluated inhaled cannabis, but oral (“edible”) preparations comprise an increasing segment of the cannabis market. To assess oral cannabis pharmacokinetics and pharmacodynamics, healthy adults (N =
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9fd3f4eb5788b6750bacfd7c88da64
https://doi.org/10.1093/jat/bkx012
https://doi.org/10.1093/jat/bkx012
Autor:
George E. Bigelow, Ryan Vandrey, John M. Mitchell, Ronald Flegel, Edward J. Cone, David J. Kuntz, Tory R. Spindle
Publikováno v:
J Anal Toxicol
Cannabis products in which cannabidiol (CBD) is the primary chemical constituent (CBD-dominant) are increasingly popular and widely available. The impact of CBD exposure on urine drug testing has not been well studied. This study characterized the ur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7228347b9d10ac9d78b04d82c30affee
https://pubmed.ncbi.nlm.nih.gov/31682266
https://pubmed.ncbi.nlm.nih.gov/31682266
Autor:
Edward J. Cone, Ryan Vandrey, John M. Mitchell, Nicolas J. Schlienz, Eugene D Hayes, George E. Bigelow, Tory R. Spindle, Ronald Flegel
Publikováno v:
J Anal Toxicol
As cannabis has become more accessible, use of alternative methods for cannabis administration such as vaporizers has become more prevalent. Most prior controlled pharmacokinetic evaluations have examined smoked cannabis in frequent (often daily) can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4344976fa6f67a6e6b8202e2183136d3
https://pubmed.ncbi.nlm.nih.gov/31095692
https://pubmed.ncbi.nlm.nih.gov/31095692
Autor:
John M. Mitchell, Ronald Flegel, Nicolas J. Schlienz, Ryan Vandrey, Tory R. Spindle, Edward J. Cone, Eugene D Hayes, George E. Bigelow
Publikováno v:
J Anal Toxicol
Currently, an unprecedented number of individuals can legally access cannabis. Vaporization is increasingly popular as a method to self-administer cannabis, partly due to perception of reduced harm compared with smoking. Few controlled laboratory stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ba1141440fc78342f6ef7699e82de2f
https://europepmc.org/articles/PMC6676961/
https://europepmc.org/articles/PMC6676961/
Autor:
Anne Z, DePriest, Rebecca, Heltsley, David L, Black, John M, Mitchell, Charles, LoDico, Ronald, Flegel, Edward J, Cone
Publikováno v:
Journal of Analytical Toxicology. 40:566-574
Oxymorphone (OM), a prescription opioid and metabolite of oxycodone, was included in the recently published proposed revisions to the Mandatory Guidelines for Federal Workplace Drug Testing Programs. To facilitate toxicological interpretation, this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c015ba97c36790347cf8ab25e1001dae
https://doi.org/10.1093/jat/bkw064
https://doi.org/10.1093/jat/bkw064
Autor:
Edward J. Cone, Ronald Flegel, Rebecca Heltsley, Anne Z. DePriest, Charles LoDico, John M. Mitchell, David L. Black
Publikováno v:
Journal of Analytical Toxicology. 40:575-582
Hydromorphone (HM), a prescription opioid and metabolite of morphine and hydrocodone, has been included in proposed revisions to the Mandatory Guidelines for Federal Workplace Drug Testing Programs. This study characterized the time course of HM in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc74e53edc027122d7f50abd9951923
https://doi.org/10.1093/jat/bkw066
https://doi.org/10.1093/jat/bkw066