Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Rona S. Scott"'
Autor:
Nicholas J. First, Katelyn M. Parrish, Amparo Martínez-Pérez, África González-Fernández, Sushma Bharrhan, Matthew Woolard, James B. McLachlan, Rona S. Scott, Jian Wang, Monica C. Gestal
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113294- (2023)
Summary: Bordetella spp. are respiratory pathogens equipped with immune evasion mechanisms. We previously characterized a Bordetella bronchiseptica mutant (RB50ΔbtrS) that fails to suppress host responses, leading to rapid clearance and long-lasting
Externí odkaz:
https://doaj.org/article/1873108fec1342a0bbb5576abc0ed691
Autor:
Yuping Wang, Yang Gu, David F. Lewis, Xin Gu, Karisa Brown, Courtney Lachute, Miriam Hankins, Rona S. Scott, Caitlin Busada, Danielle B. Cooper, Charles E. McCathran, Perry Barrilleaux
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
Background and objectiveCOVID-19 infection in pregnancy significantly increases risks of adverse pregnancy outcomes. However, little is known how the innate immunity at the placental maternal-fetal interface responds to COVID-19 infection. Type I IFN
Externí odkaz:
https://doaj.org/article/86643639aa334144aed0e32b9234b0e8
Publikováno v:
Viruses, Vol 14, Iss 12, p 2700 (2022)
Epstein–Barr virus (EBV) is an oncogenic human herpesvirus infecting approximately 90% of the world’s population. The oral cavity serves a central role in the life cycle, transmission, and pathogenesis of EBV. Transmitted to a new host via saliva
Externí odkaz:
https://doaj.org/article/5fd7dc15db9145b382ac6481a5791a74
Autor:
Sunitha Chandran, Robert M. Schilke, Cassidy M. R. Blackburn, Aila Yurochko, Rusella Mirza, Rona S. Scott, Brian N. Finck, Matthew D. Woolard
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Macrophage responses contribute to a diverse array of pathologies ranging from infectious disease to sterile inflammation. Polarization of macrophages determines their cellular function within biological processes. Lipin-1 is a phosphatidic acid phos
Externí odkaz:
https://doaj.org/article/2f929f1134fb4913933bcb98fe4f56da
Autor:
Mark R. Eichelberg, Rene Welch, J. Tod Guidry, Ahmed Ali, Makoto Ohashi, Kathleen R. Makielski, Kyle McChesney, Nicholas Van Sciver, Paul F. Lambert, Sündüz Keleș, Shannon C. Kenney, Rona S. Scott, Eric Johannsen
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Epstein-Barr virus (EBV) is a human herpesvirus that is associated with lymphomas as well as nasopharyngeal and gastric carcinomas. Although carcinomas account for almost 90% of EBV-associated cancers, progress in examining EBV’s role in t
Externí odkaz:
https://doaj.org/article/23bfdf5ee4d64f5eb94ddf1bfd5f97d5
Publikováno v:
PLoS Pathogens, Vol 19, Iss 12, p e1011873 (2023)
As a human tumor virus, EBV is present as a latent infection in its associated malignancies where genetic and epigenetic changes have been shown to impede cellular differentiation and viral reactivation. We reported previously that levels of the Wnt
Externí odkaz:
https://doaj.org/article/78110df1e40b4462a85016310db1dd71
Publikováno v:
Journal of Virology.
It is being assumed that human papillomavirus (HPV) utilizes three different modes of replication during its life cycle: initial amplification during the establishment phase, genome maintenance, and differentiation-induced amplification. However, HPV
Publikováno v:
Journal of Virology. 97
HPV genome maintenance is currently thought to be achieved by regulating the expression and activity of the viral replication factors E1 and E2. In addition, the E8^E2 repressor has been shown to be important for restricting genome copy numbers by co
Autor:
Julia E. Myers, Danielle L. Schaal, Ebubechukwu H. Nkadi, B. J. H. Ward, Malgorzata Bienkowska-Haba, Martin Sapp, Jason M. Bodily, Rona S. Scott
Publikováno v:
Journal of Virology. 97
Terminally differentiated epithelium is known to support EBV genome amplification and virion morphogenesis following infection. The contribution of the cell cycle in differentiated tissues to efficient EBV replication is not understood.