Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Ron-Patrick Cadeddu"'
Autor:
Thomas Schroeder, Matthias Stelljes, Maximilian Christopeit, Eva Esseling, Christoph Scheid, Jan-Henrik Mikesch, Christina Rautenberg, Paul Jäger, Ron-Patrick Cadeddu, Nadja Drusenheimer, Udo Holtick, Stefan Klein, Rudolf Trenschel, Rainer Haas, Ulrich Germing, Nicolaus Kröger, Guido Kobbe
Publikováno v:
Haematologica, Vol 108, Iss 11 (2023)
Azacitidine (Aza) combined with donor lymphocyte infusions (DLI) is an established treatment for relapse of myeloid malignancies after allogeneic transplantation. Based on its immunomodulatory and anti-leukemic properties we considered Lenalidomide (
Externí odkaz:
https://doaj.org/article/a0b5dba7ca854719927a4d419f0115af
Autor:
Stefan Fasbender, Lisa Zimmermann, Ron-Patrick Cadeddu, Martina Luysberg, Bastian Moll, Christoph Janiak, Thomas Heinzel, Rainer Haas
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Abstract Graphene quantum dots (GQDs) are a promising next generation nanomaterial with manifold biomedical applications. For real world applications, comprehensive studies on their influence on the functionality of primary human cells are mandatory.
Externí odkaz:
https://doaj.org/article/88ad72d70dcb4bbf89839d764d7aff1e
Autor:
Saskia Mayer, Marie Prechtl, Pia Liebfried, Ron-Patrick Cadeddu, Fabian Stuhldreier, Matthias Kohl, Folker Wenzel, Björn Stork, Sebastian Wesselborg, Peter Proksch, Ulrich Germing, Rainer Haas, Paul Jäger
Publikováno v:
Marine Drugs, Vol 17, Iss 9, p 521 (2019)
There is a variety of antineoplastic drugs that are based on natural compounds from ecological niches with high evolutionary pressure. We used two cell lines (Jurkat J16 and Ramos) in a screening to assess 300 different naturally occurring compounds
Externí odkaz:
https://doaj.org/article/8ffbe63f31874f16b211cfb5d27a7f48
Autor:
Patrick Petzsch, Paul Jäger, Dagmar Wieczorek, Guido Kobbe, Karl Köhrer, Ron-Patrick Cadeddu, Ulrich Germing, Rainer Haas, Christoph Zilkens, Thomas Schroeder, Pablo Rabes, Christina Rautenberg, Barbara Hildebrandt, Beate Betz, Annemarie Koch, Harald Surowy, Sören Twarock, Stefanie Geyh, Tobias Hesper, Uwe Maus, Felix Bormann
Publikováno v:
Stem Cells. 39:1270-1284
Acute myeloid leukemia (AML) is characterized by an expansion of leukemic cells and a simultaneous reduction of normal hematopoietic precursors in the bone marrow (BM) resulting in hematopoietic insufficiency, but the underlying mechanisms are poorly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a7426c9e05afe869104a6a07152130
https://doi.org/10.1002/stem.3387
https://doi.org/10.1002/stem.3387
Autor:
Norbert Gattermann, Ron-Patrick Cadeddu, Oumaima Stambouli, Simon Kai Brille, Jasmin Ewert, Ulrich Germing, Bernd Giebel, Robert Zeiser, Fatemeh Majidi
Introduction: Antitumor activity of the neddylation inhibitor pevonedistat has been documented in several hematologic and non-hematologic malignancies. Unexpectedly, Zhou et al (PNAS, 2016) discovered a dose-dependent biphasic effect of pevonedistat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3613375bbf86c1b4c223e291cc808f3c
Autor:
Ron-Patrick Cadeddu, Thomas Heinzel, Katharina Raba, Christian Wimmenauer, Bekir Bulat, Martina Luysberg, Sonja Allani, Claus A. M. Seidel, Rainer Haas, Johannes C. Fischer, Stefan Fasbender
Publikováno v:
RSC Advances 7(20), 12208-12216 (2017). doi:10.1039/C6RA27829A
Human leukocytes obtained from samples of leukapheresis products of three healthy donors stimulated by granulocyte colony stimulating factor (G-CSF) were exposed to graphene quantum dots. A time- and concentration dependent uptake was observed with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420fc512b5cf8927d04b307779b0fa9b
https://doi.org/10.1039/c6ra27829a
https://doi.org/10.1039/c6ra27829a
Autor:
Norbert Gattermann, Julia Fröbel, Ron-Patrick Cadeddu, Hubert Schelzig, Carolin Brings, Rainer Haas
Publikováno v:
Blood. 136:5-6
Introduction Increased susceptibility to infections in MDS is due to neutropenia as well as functional impairment of neutrophils. We investigated whether neutrophil dysfunction includes diminished formation of neutrophil extracellular traps (NETs). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa16653472fc431255fd349917b323d1
https://doi.org/10.1182/blood-2020-138409
https://doi.org/10.1182/blood-2020-138409
Autor:
Pia Liebfried, Sebastian Wesselborg, Saskia Mayer, Marie Prechtl, Björn Stork, Ron-Patrick Cadeddu, Folker Wenzel, Matthias Kohl, Paul Jäger, Fabian Stuhldreier, Peter Proksch, Ulrich Germing, Rainer Haas
Publikováno v:
Marine Drugs
Volume 17
Issue 9
Marine Drugs, Vol 17, Iss 9, p 521 (2019)
Volume 17
Issue 9
Marine Drugs, Vol 17, Iss 9, p 521 (2019)
There is a variety of antineoplastic drugs that are based on natural compounds from ecological niches with high evolutionary pressure. We used two cell lines (Jurkat J16 and Ramos) in a screening to assess 300 different naturally occurring compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5660199d9870ec74c22ce081fe1b6ec
Autor:
Ariane Dienst, Ingmar Bruns, Ron-Patrick Cadeddu, Guido Kobbe, Christian Matthias Wilk, Roland Fenk, Tobias Strapatsas, Rainer Haas, Niklas Heinzler, Karl Köhrer, Thomas Schroeder, René Deenen, Fatemeh Majidi, Amelie Boquoi
Publikováno v:
International Journal of Cancer. 139:2343-2352
New drugs for the treatment of multiple myeloma (MM) comprise immunomodulatory substances such as lenalidomide and related compounds. While lenalidomide has found its way into first-line treatment as well as into relapse therapy, little is known abou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8956572c680fb91075cca176ac67dd0c
https://doi.org/10.1002/ijc.30257
https://doi.org/10.1002/ijc.30257
Autor:
Ron-Patrick Cadeddu, Christoph Zilkens, Tobias Schroeder, Ulrich Germing, Rainer Haas, Stefanie Geyh, Paul Jäger, Roland Fenk, Cyrus Khandanpour, D. Hermsen, Frank Lyko, Guido Kobbe, Julian Gutekunst, C. M. Wilk, Manuel Rodríguez-Paredes
Publikováno v:
Leukemia. 30:683-691
Hematopoietic insufficiency is the hallmark of acute myeloid leukemia (AML) and predisposes patients to life-threatening complications such as bleeding and infections. Addressing the contribution of mesenchymal stromal cells (MSC) to AML-induced hema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81fb020fd2a48a3cb0328ed0742331ba
https://doi.org/10.1038/leu.2015.325
https://doi.org/10.1038/leu.2015.325