Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Ron Unger"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1244-1259 (2024)
Understanding protein-protein interactions (PPIs) at the molecular level may lead to innovations in medicine and biochemistry. The assumption that there are certain “hot spots” on protein surfaces that mediate their interactions with other protei
Externí odkaz:
https://doaj.org/article/4ef4296776284edab83042250479b31f
Autor:
Ilan Schrier, Orel Slotki-Itzchakov, Yoav Elkis, Nofar Most-Menachem, Orit Adato, Debora Fitoussi-Allouche, Sally Shpungin, Ron Unger, Uri Nir
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers with a high percentage of morbidity. The deciphering and identification of novel targets and tools for intervening with its adverse progression are therefore of immense importanc
Externí odkaz:
https://doaj.org/article/c8b76b73e1184918b5f451074bc401ac
Autor:
K. Shanmugha Rajan, Saurav Aryal, Disha-Gajanan Hiregange, Anat Bashan, Hava Madmoni, Mika Olami, Tirza Doniger, Smadar Cohen-Chalamish, Pascal Pescher, Masato Taoka, Yuko Nobe, Aliza Fedorenko, Tanaya Bose, Ella Zimermann, Eric Prina, Noa Aharon-Hefetz, Yitzhak Pilpel, Toshiaki Isobe, Ron Unger, Gerald F. Späth, Ada Yonath, Shulamit Michaeli
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114203- (2024)
Summary: Leishmania is the causative agent of cutaneous and visceral diseases affecting millions of individuals worldwide. Pseudouridine (Ψ), the most abundant modification on rRNA, changes during the parasite life cycle. Alterations in the level of
Externí odkaz:
https://doaj.org/article/1af39d1e364149228194dd16b1cc4963
Autor:
K. Shanmugha Rajan, Hava Madmoni, Anat Bashan, Masato Taoka, Saurav Aryal, Yuko Nobe, Tirza Doniger, Beathrice Galili Kostin, Amit Blumberg, Smadar Cohen-Chalamish, Schraga Schwartz, Andre Rivalta, Ella Zimmerman, Ron Unger, Toshiaki Isobe, Ada Yonath, Shulamit Michaeli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Trypanosomes are protozoan parasites that cycle between insect and mammalian hosts and are the causative agent of sleeping sickness. Here, we describe the changes of pseudouridine (Ψ) modification on rRNA in the two life stages of the paras
Externí odkaz:
https://doaj.org/article/13fe9a6c17164bf5b6d6496ccbcea44a
Autor:
Shahar Talisman, Joshua Guedalia, Rivka Farkash, Tehila Avitan, Naama Srebnik, Yair Kasirer, Michael S. Schimmel, Donia Ghanem, Ron Unger, Sorina Grisaru Granovsky
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Neonatal intensive care unit (NICU) admission among term neonates is a rare event. The aim of this study was to study the association of the NICU admission of term neonates on the risk of long-term childhood mortality. Methods A s
Externí odkaz:
https://doaj.org/article/acc4ad3dcbd04981931e5846f341e058
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-4 (2023)
Abstract Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) is a membrane protein expressed on immune cells, involved in neurodegenerative diseases and cancer. Recently, it was shown that TREM2 is expressed on lipid associated macrophages in ad
Externí odkaz:
https://doaj.org/article/93570d2135df41759e2ef02571454682
Autor:
Orit Adato, Ronen Brenner, Avi Levy, Yael Shinar, Asaf Shemer, Shalem Dvir, Ilan Ben-Zvi, Avi Livneh, Ron Unger, Shaye Kivity
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract A growing number of familial Mediterranean fever (FMF) patients in Israel do not have a single country of origin for all four grandparents. We aimed to predict the Mediterranean fever gene (MEFV) variant most likely to be found for an indivi
Externí odkaz:
https://doaj.org/article/2660e2e1df2f4b53a3794ba9a2209b4a
Autor:
Rephael Nizar, Simona Cazacu, Cunli Xiang, Matan Krasner, Efrat Barbiro-Michaely, Doron Gerber, Jonathan Schwartz, Iris Fried, Shira Yuval, Aharon Brodie, Gila Kazimirsky, Naama Amos, Ron Unger, Stephen Brown, Lisa Rogers, Donald H. Penning, Chaya Brodie
Publikováno v:
Cells, Vol 12, Iss 15, p 1921 (2023)
Glioblastoma (GBM) is the most common and aggressive primary brain tumor. GBM contains a small subpopulation of glioma stem cells (GSCs) that are implicated in treatment resistance, tumor infiltration, and recurrence, and are thereby considered impor
Externí odkaz:
https://doaj.org/article/7fc56804bc854fe7ae986e35e6d87c7e
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/a1a1d25674b548ddb4ca2751d59de486
Autor:
Laura Piel, K Shanmugha Rajan, Giovanni Bussotti, Hugo Varet, Rachel Legendre, Caroline Proux, Thibaut Douché, Quentin Giai-Gianetto, Thibault Chaze, Thomas Cokelaer, Barbora Vojtkova, Nadav Gordon-Bar, Tirza Doniger, Smadar Cohen-Chalamish, Praveenkumar Rengaraj, Céline Besse, Anne Boland, Jovana Sadlova, Jean-François Deleuze, Mariette Matondo, Ron Unger, Petr Volf, Shulamit Michaeli, Pascale Pescher, Gerald F Späth
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010375 (2022)
The protozoan parasite Leishmania donovani causes fatal human visceral leishmaniasis in absence of treatment. Genome instability has been recognized as a driver in Leishmania fitness gain in response to environmental change or chemotherapy. How genom
Externí odkaz:
https://doaj.org/article/6054875378b740aabcc0a4e834d05c3b