Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ron Skupsky"'
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 7, p e1003135 (2013)
The sequence of a promoter within a genome does not uniquely determine gene expression levels and their variability; rather, promoter sequence can additionally interact with its location in the genome, or genomic context, to shape eukaryotic gene exp
Externí odkaz:
https://doaj.org/article/26b6e35ac3ee46659e5750fc57823026
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 9, p e1000952 (2010)
Mammalian gene expression patterns, and their variability across populations of cells, are regulated by factors specific to each gene in concert with its surrounding cellular and genomic environment. Lentiviruses such as HIV integrate their genomes i
Externí odkaz:
https://doaj.org/article/d737e15ed4f3462a9315f3d4f489e9db
Publikováno v:
Journal of Theoretical Biology. 247:242-258
We apply linear-stability theory and perform perturbation studies to better characterize, and to generate new experimental predictions from, a model of chemotactic gradient sensing in eukaryotic cells. The model uses reaction-diffusion equations to d
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 9 (2010)
PLoS computational biology, vol 6, iss 9
PLoS Computational Biology
PLoS computational biology, vol 6, iss 9
PLoS Computational Biology
Mammalian gene expression patterns, and their variability across populations of cells, are regulated by factors specific to each gene in concert with its surrounding cellular and genomic environment. Lentiviruses such as HIV integrate their genomes i
Publikováno v:
Biophysical journal. 89(4)
We develop a mathematical model of phosphoinositide-mediated gradient sensing that can be applied to chemotactic behavior in highly motile eukaryotic cells such as Dictyostelium and neutrophils. We generate four variants of our model by adjusting par
Publikováno v:
SPIE Proceedings.
The aim of our work is to develop new optical tools to quantify parameters that may enter into models of cell motion in response to chemical gradients (chemotaxis). Dictyostelium discoidium is a well-known model organism for studying chemotaxis. We h
Publikováno v:
PLoS computational biology, vol 9, iss 7
PLoS Computational Biology
PLoS Computational Biology, Vol 9, Iss 7, p e1003135 (2013)
PLoS Computational Biology
PLoS Computational Biology, Vol 9, Iss 7, p e1003135 (2013)
The sequence of a promoter within a genome does not uniquely determine gene expression levels and their variability; rather, promoter sequence can additionally interact with its location in the genome, or genomic context, to shape eukaryotic gene exp