Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Ron Shah"'
Publikováno v:
ACS Central Science, Vol 4, Iss 3, Pp 387-396 (2018)
Externí odkaz:
https://doaj.org/article/f6707d7c21a34f049ab8f07ebaeb05db
Autor:
Omkar Zilka, Ron Shah, Bo Li, José Pedro Friedmann Angeli, Markus Griesser, Marcus Conrad, Derek A. Pratt
Publikováno v:
ACS Central Science, Vol 3, Iss 3, Pp 232-243 (2017)
Externí odkaz:
https://doaj.org/article/4d543a4edba7430aa1505f18947779f2
Publikováno v:
The Journal of organic chemistry. 86(9)
Alkylated diphenylamines are among the most efficacious radical-trapping antioxidants (RTAs) for applications at elevated temperatures since they are able to trap multiple radical equivalents due to catalytic cycles involving persistent diphenylnitro
Autor:
Andreia Silveira, Imke Greving, Elena Longo, Mario Scheel, Timm Weitkamp, Claudia Fleck, Ron Shahar, Paul Zaslansky
Publikováno v:
Journal of Synchrotron Radiation, Vol 31, Iss 1, Pp 136-149 (2024)
Bone material contains a hierarchical network of micro- and nano-cavities and channels, known as the lacuna-canalicular network (LCN), that is thought to play an important role in mechanobiology and turnover. The LCN comprises micrometer-sized lacuna
Externí odkaz:
https://doaj.org/article/10e6c39d93ba4a88accd0b42ab14a9a4
Autor:
Omkar Zilka, Markus Griesser, Ron Shah, Antonius T. M. Van Kessel, Evan A. Haidasz, Derek A. Pratt
Publikováno v:
Journal of the American Chemical Society. 140:3798-3808
Sterically-hindered nitroxides such as 2,2,6,6-tetramethylpiperidin-N-oxyl (TEMPO) have long been ascribed antioxidant activity that is thought to underlie their chemopreventive and anti-aging properties. However, the most commonly invoked reactions
Autor:
Marcus Conrad, Thibaut Vignane, José Pedro Friedmann Angeli, Valerie B. O'Donnell, Christina Scheel, Aloys Schepers, Markus Rehberg, Milene Costa da Silva, Almut Schulze, Werner Schmitz, Daniel A. White, Andrea Goya Grocin, Elena Panzilius, Katalin Buday, Andreas Kurz, Mami Sato, Sebastian Doll, Thamara Nishida Xavier da Silva, Grzegorz M. Popowicz, Ron Shah, Bettina Proneth, Derek A. Pratt, Maceler Aldrovandi, André Mourão, Michael Sattler, Edward W. Tate, Irina Ingold, Florencio Porto Freitas, Jonas Wanninger, Andrew Flatley, Vaishnavi Mohana, Markus Sauer
Publikováno v:
Nature 575, 693-698 (2019)
Ferroptosis is an iron-dependent form of necrotic cell death marked by oxidative damage to phospholipids1,2. To date, ferroptosis has been thought to be controlled only by the phospholipid hydroperoxide-reducing enzyme glutathione peroxidase 4 (GPX4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85fd0dc662e86b7e39048146453fa89
http://hdl.handle.net/10044/1/75345
http://hdl.handle.net/10044/1/75345
Publikováno v:
Cell Chemical Biology. 26:1594-1607.e7
Summary “Antioxidant activity” is an often invoked, but generally poorly characterized, molecular property. Several assays are available to determine antioxidant activity, the most popular of which is based upon the ability of a putative antioxid
Publikováno v:
ACS chemical biology. 12(10)
Two aromatic amines (ferrostatin-1 and liproxstatin-1) were recently identified from high-throughput screening efforts to uncover potent inhibitors of ferroptosis, the necrotic-like cell death induced by inhibition of glutathione peroxidase 4 (GPX4),
Publikováno v:
Trends Pharmacol. Sci. 38, 489-498 (2017)
The past decade has yielded tremendous insights into how cells die. This has come with our understanding that several distinct forms of cell death are encompassed under the umbrella term necrosis. Among these distinct forms of regulated necrotic cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::668ed5eaa184c15c1516e8b070fea7b6
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=50836
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=50836
Autor:
Ron Shah, Derek A. Pratt
Publikováno v:
The Journal of organic chemistry. 81(15)
Hydroperoxides and carboxylic acids are key primary products that arise in the autoxidation of hydrocarbons. We have developed a simple approach to rapidly and simultaneously determine both types of products using hydroperoxide- and acid-sensitive mo