Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Ron S. Weening"'
Autor:
J Merlijn van den Berg, Elsbeth van Koppen, Anders Ahlin, Bernd H Belohradsky, Ewa Bernatowska, Lucien Corbeel, Teresa Español, Alain Fischer, Magdalena Kurenko-Deptuch, Richard Mouy, Theoni Petropoulou, Joachim Roesler, Reinhard Seger, Marie-José Stasia, Niels H Valerius, Ron S Weening, Baruch Wolach, Dirk Roos, Taco W Kuijpers
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5234 (2009)
CGD is an immunodeficiency caused by deletions or mutations in genes that encode subunits of the leukocyte NADPH oxidase complex. Normally, assembly of the NADPH oxidase complex in phagosomes of certain phagocytic cells leads to a "respiratory burst"
Externí odkaz:
https://doaj.org/article/0e663008f09b445ca39a8b97a56d5380
Autor:
Ilhan Tezcan, Dirk Roos, Ozden Sanal, S. Simsek, Martin de Boer, Christof Meischl, S.K.Alex Law, Ron S. Weening, Tayfun Güngör
Publikováno v:
Experimental Hematology. 30:252-261
Objective. The aim of this study was to analyze mutations in DNA from patients with leukocyte adhesion deficiency (LAD), an immunodeficiency caused by absence of the β 2 subunit (CD18) of the leukocyte integrins LFA-1 (CD11a/CD18), Mac-1 (CD11b/CD18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55226d743b35d562bc44afc0c3ca66b5
https://doi.org/10.1016/s0301-472x(01)00782-2
https://doi.org/10.1016/s0301-472x(01)00782-2
Publikováno v:
Clinical and experimental immunology, 122(3), 410-417. Wiley-Blackwell
SUMMARY Chronic granulomatous disease (CGD) is a clinical syndrome of recurrent bacterial and fungal infections caused by a rare disorder of phagocytic cells. In CGD, the phagocytes are unable to generate oxygen radicals after stimulation of these ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8080955935d590c54dbf2b45b5b26c8b
https://doi.org/10.1046/j.1365-2249.2000.01405.x
https://doi.org/10.1046/j.1365-2249.2000.01405.x
Autor:
Arthur J. Verhoeven, Ron S. Weening, L Y Thung, M de Boer, R. A. W. Van Lier, Dörte Hamann, Taco W. Kuijpers, Dirk Roos
Publikováno v:
Journal of clinical investigation, 100(7), 1725-1733. The American Society for Clinical Investigation
Leukocyte adhesion deficiency (LAD) is characterized by the inability of leukocytes, in particular neutrophilic granulocytes, to emigrate from the bloodstream towards sites of inflammation. Infectious foci are nonpurulent and may eventually become ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aac7cd785d40737a73867034cd63291
https://doi.org/10.1172/jci119697
https://doi.org/10.1172/jci119697
Autor:
W Stuve, Ron S. Weening
Publikováno v:
Pediatric Hematology and Oncology. 14:199-203
In 1988 the Emma Children's Hospital and the department of pediatrics of the Academic Medical Center in Amsterdam (The Netherlands) merged. With the integration of the Emma Children's Hospital and the academic pediatric department, an academic childr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c335106020bed23cfde00754b656c47a
https://doi.org/10.3109/08880019709009489
https://doi.org/10.3109/08880019709009489
Publikováno v:
Pediatric hematology and oncology, 14(6), 539-545. Informa Healthcare
Neutropenia is one of the risk factors for severe therapy-related morbidity in childhood malignancies. We have studied the potential of GM-CSF to shorten the neutropenic period after normal-dose chemotherapy in children who were treated for solid tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::275250d968bf3824524f0fdb7f31111f
https://doi.org/10.3109/08880019709030910
https://doi.org/10.3109/08880019709030910
Publikováno v:
Journal of Leukocyte Biology. 60:716-720
Daring the international placebo-controlled trial on the efficacy of interferon-γ (IFN-γ) in chronic granulomatous disease (CGD), 19 patients entered the study via our Institute. One patient stopped treatment shortly thereafter. RNA was purified fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edfe524173efb132906ad44631e76090
https://doi.org/10.1002/jlb.60.6.716
https://doi.org/10.1002/jlb.60.6.716
Autor:
Ron S. Weening, Anders Åhlin, Anthony W. Segal, M de Boer, E Bernatowska-Matuszkiewicz, Futoshi Kuribayashi, JP Hossle, H Middleton-Price, K Nemet, Dirk Roos, Christof Meischl
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af3fcabab606d404f704c573ad411b03
https://doi.org/10.1182/blood.v87.5.1663.1663
https://doi.org/10.1182/blood.v87.5.1663.1663
Publikováno v:
The Netherlands Journal of Medicine. 46:193-196
A 31-year-old patient was recurrently admitted because of pneumonia. Specialised leukocyte function tests revealed the diagnosis of an X-linked type of chronic granulomatous disease. Treatment with interferon-gamma successfully prevented new infectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c610df78baea63e59d70d7e5b3cc365
https://doi.org/10.1016/0300-2977(94)00088-q
https://doi.org/10.1016/0300-2977(94)00088-q
Autor:
Wilhelm Kaulfersch, P. M. Hilarius, Ben G.J.M. Bolscher, Ron S. Weening, Reinhard A. Seger, Dirk Roos, Arthur J. Verhoeven, Jeanette H. W. Leusen
Publikováno v:
The Journal of Experimental Medicine
Journal of experimental medicine, 180(6), 2329-2334. Rockefeller University Press
Journal of experimental medicine, 180(6), 2329-2334. Rockefeller University Press
Src homology 3 (SH3) domains have been suggested to play an important role in the assembly of the superoxide-forming nicotinamide adenine dinucleotide phosphate (NADPH) oxidase upon activation of phagocytes, which involves the association of membrane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff504551ff0716890540ff939b8f5a6b
http://europepmc.org/articles/PMC2191792
http://europepmc.org/articles/PMC2191792