Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Ron Rotkopf"'
Autor:
Lior Aram, Diede de Haan, Neta Varsano, James B. Gilchrist, Christoph Heintze, Ron Rotkopf, Katya Rechav, Nadav Elad, Nils Kröger, Assaf Gal
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Silica cell-wall formation in diatoms is a showcase for the ability of organisms to control inorganic mineralization. The process of silicification by these unicellular algae is tightly regulated within a membrane-bound organelle, the silica
Externí odkaz:
https://doaj.org/article/cd7138a1a6e7438db6e193c6f497ea13
Autor:
Diede de Haan, Lior Aram, Hadas Peled-Zehavi, Yoseph Addadi, Oz Ben-Joseph, Ron Rotkopf, Nadav Elad, Katya Rechav, Assaf Gal
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Exocytosis is a fundamental cellular process. Here, the authors report an unusual exocytosis mechanism in the silicified cell wall of diatoms, in which membrane patches are discarded.
Externí odkaz:
https://doaj.org/article/bba4042c8fe14d21b392f34ddff859be
Autor:
Abel Cruz Camacho, Edo Kiper, Sonia Oren, Nir Zaharoni, Netta Nir, Noam Soffer, Yael Noy, Bar Ben David, Anna Rivkin, Ron Rotkopf, Dan Michael, Teresa G. Carvalho, Neta Regev-Rudzki
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-25 (2023)
Abstract Background Plasmodium falciparum (Pf) is the leading protozoan causing malaria, the most devastating parasitic disease. To ensure transmission, a small subset of Pf parasites differentiate into the sexual forms (gametocytes). Since the abund
Externí odkaz:
https://doaj.org/article/4f78c56cab9b477480c4a350d020036c
Autor:
Yifat Ofir-Birin, Hila Ben Ami Pilo, Abel Cruz Camacho, Ariel Rudik, Anna Rivkin, Or-Yam Revach, Netta Nir, Tal Block Tamin, Paula Abou Karam, Edo Kiper, Yoav Peleg, Reinat Nevo, Aryeh Solomon, Tal Havkin-Solomon, Alicia Rojas, Ron Rotkopf, Ziv Porat, Dror Avni, Eli Schwartz, Thomas Zillinger, Gunther Hartmann, Antonella Di Pizio, Neils Ben Quashie, Rivka Dikstein, Motti Gerlic, Ana Claudia Torrecilhas, Carmit Levy, Esther N. M. Nolte-‘t Hoen, Andrew G. Bowie, Neta Regev-Rudzki
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The chemokine CXCL10 is associated with pathogenesis of cerebral malaria in Plasmodium falciparum infection. Here the authors show that P. falciparum produces extracellular vesicles laden with RNAs that are taken up by monocytes resulting in a RIG-I
Externí odkaz:
https://doaj.org/article/224e6a94586f481d8f075fa74b8e8bf3
Autor:
Tomer Mevorach, Michal Taler, Shira Dar, Maya Lebow, Irit Schorr Sapir, Ron Rotkopf, Alan Apter, Silvana Fennig, Alon Chen, Abraham Weizman, Maya Amitai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Recent studies suggest immune function dysregulation in depression and anxiety disorders. Elevated pro-inflammatory cytokines may be a marker for immune system dysregulation. No study assessed the correlation between the levels of cytokines
Externí odkaz:
https://doaj.org/article/3873701230bb481fafbbf8668c878f59
Autor:
Elya Dekel, Dana Yaffe, Irit Rosenhek-Goldian, Gili Ben-Nissan, Yifat Ofir-Birin, Mattia I. Morandi, Tamar Ziv, Xavier Sisquella, Matthew A. Pimentel, Thomas Nebl, Eugene Kapp, Yael Ohana Daniel, Paula Abou Karam, Daniel Alfandari, Ron Rotkopf, Shimrit Malihi, Tal Block Temin, Debakshi Mullick, Or-Yam Revach, Ariel Rudik, Nir S. Gov, Ido Azuri, Ziv Porat, Giulia Bergamaschi, Raya Sorkin, Gijs J. L. Wuite, Ori Avinoam, Teresa G. Carvalho, Sidney R. Cohen, Michal Sharon, Neta Regev-Rudzki
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Plasmodium falciparum secretes extracellular vesicles (EVs) while growing inside red blood cells (RBCs). Here the authors show that these EVs contain assembled and functional 20S proteasome complexes that remodel the cytoskeleton of naïve human RBCs
Externí odkaz:
https://doaj.org/article/2714bdc7c6d440079ba403f2120173c1
Autor:
Hila Ben Ami Pilo, Sana Khan Khilji, Jost Lühle, Karina Biskup, Bar Levy Gal, Irit Rosenhek Goldian, Daniel Alfandari, Or‐Yam Revach, Edo Kiper, Mattia I. Morandi, Ron Rotkopf, Ziv Porat, Véronique Blanchard, Peter H. Seeberger, Neta Regev‐Rudzki, Oren Moscovitz
Publikováno v:
Journal of Extracellular Biology, Vol 1, Iss 2, Pp n/a-n/a (2022)
Abstract Glycoconjugates on extracellular vesicles (EVs) play a vital role in internalization and mediate interaction as well as regulation of the host immune system by viruses, bacteria, and parasites. During their intraerythrocytic life‐cycle sta
Externí odkaz:
https://doaj.org/article/bcd25f6a2e4b41ef864eb546069cfeda
Efficacy of Ciprofloxacin/Celecoxib combination in zebrafish models of amyotrophic lateral sclerosis
Autor:
Hagit Goldshtein, Alexandre Muhire, Virginie Petel Légaré, Avital Pushett, Ron Rotkopf, Jeremy M. Shefner, Randall T Peterson, Gary A. B. Armstrong, Niva Russek‐ Blum
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 10, Pp 1883-1897 (2020)
Abstract Objective To evaluate the efficacy of a fixed‐dose combination of two approved drugs, Ciprofloxacin and Celecoxib, as a potential therapeutic treatment for amyotrophic lateral sclerosis (ALS). Methods Toxicity and efficacy of Ciprofloxacin
Externí odkaz:
https://doaj.org/article/b113a40b6b6d4087b0de396e6c9a5c30
Autor:
Eran Assaraf, Ronen Blecher, Lia Heinemann-Yerushalmi, Sharon Krief, Ron Carmel Vinestock, Inbal E. Biton, Vlad Brumfeld, Ron Rotkopf, Erez Avisar, Gabriel Agar, Elazar Zelzer
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Mutations in human PIEZO2, encoding for a mechanosensitive ion channel, lead to skeletal abnormalities including scoliosis and hip dysplasia. Here, the authors show that deletion of Piezo2 in proprioceptive neurons, but not in skeletal lineages, reca
Externí odkaz:
https://doaj.org/article/f2eadef4102943bfaa0c0612f6af5ecb
Autor:
Daniel Alfandari, Hila Ben Ami Pilo, Paula Abou Karam, Osnat Dagan, Carine Joubran, Ron Rotkopf, Neta Regev-Rudzki, Ziv Porat
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Extracellular vesicles (EVs) are produced by across almost all the living kingdoms and play a crucial role in cell-cell communication processes. EVs are especially important for pathogens, as Plasmodium falciparum (Pf) parasite, the leading causing s
Externí odkaz:
https://doaj.org/article/31123daf3de841f4b3b7bee5455c0d47