Zobrazeno 1 - 10 of 28 pro vyhledávání: '"Ron Piran"'
1
Akademický článek
Par2-mediated responses in inflammation and regeneration: choosing between repair and damage
Autor: Gal Reches, Ron Piran
Publikováno v: Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-15 (2024)
Abstract The protease activated receptor 2 (Par2) plays a pivotal role in various damage models, influencing injury, proliferation, inflammation, and regeneration. Despite extensive studies, its binary roles— EITHER aggravating injury or promoting
Externí odkaz: https://doaj.org/article/128853e09af04f8abe8c9bac9ccf62a4
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2
Akademický článek
Controlling autoimmune diabetes onset by targeting Protease-Activated Receptor 2
Autor: Gal Reches, Lynn Khoon, Narmeen Ghanayiem, Assaf Malka, Ron Piran
Publikováno v: Biomedicine & Pharmacotherapy, Vol 175, Iss , Pp 116622- (2024)
Background: Type 1 diabetes (T1D) is a challenging autoimmune disease, characterized by an immune system assault on insulin-producing β-cells. As insulin facilitates glucose absorption into cells and tissues, β-cell deficiency leads to elevated blo
Externí odkaz: https://doaj.org/article/057c94efd7544f7f916eec1ae6cb0856
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3
Akademický článek
Resolving the conflicts around Par2 opposing roles in regeneration by comparing immune-mediated and toxic-induced injuries
Autor: Gal Reches, Netta R. Blondheim Shraga, Florent Carrette, Assaf Malka, Natalia Saleev, Yehuda Gubbay, Offir Ertracht, Izhak Haviv, Linda M. Bradley, Fred Levine, Ron Piran
Publikováno v: Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-20 (2022)
Abstract Background Different factors may lead to hepatitis. Among which are liver inflammation and poisoning. We chose two hepatitis models, typical for these two underlying causes. Thus, we aimed to characterize the role of protease-activated recep
Externí odkaz: https://doaj.org/article/3aba8cd15bd7498c934b490029892569
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4
Akademický článek
Gestational diabetes induces behavioral and brain gene transcription dysregulation in adult offspring
Autor: Keren Aviel-Shekler, Yara Hamshawi, Worood Sirhan, Dmitriy Getselter, Kolluru D. Srikanth, Assaf Malka, Ron Piran, Evan Elliott
Publikováno v: Translational Psychiatry, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract The etiology of Autism Spectrum Disorders (ASD) includes a strong genetic component and a complicated environmental component. Recent evidence indicates that maternal diabetes, including gestational diabetes, is associated with an increased
Externí odkaz: https://doaj.org/article/6514e744d9b54a94bce58bb7917cd664
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6
Current Approaches in Diabetes Treatment and Other Strategies to Reach Normoglycemia
Autor: Ron Piran, Worood Sirhan
Publikováno v: Current Topics in Medicinal Chemistry. 20:2922-2944
Cells are mainly dependent on glucose as their energy source. Multicellular organisms need to adequately control individual glucose uptake by the cells, and the insulin-glucagon endocrine system serves as the key glucose regulation mechanism. Insulin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f4093f5640950245da5fb7a62e16e99
https://doi.org/10.2174/1568026620666200716113813
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