Výsledky vyhledávání - "Ron P Schuring"

Akademický článek

The prevalence of previously undiagnosed leprosy in the general population of northwest bangladesh.

Autor: Fake J Moet, Ron P Schuring, David Pahan, Linda Oskam, Jan Hendrik Richardus

Publikováno v: PLoS Neglected Tropical Diseases, Vol 2, Iss 2, p e198 (2008)

BACKGROUND: The prevalence of previously undiagnosed leprosy (PPUL) in the general population was determined to estimate the background level of leprosy in the population and to compare this with registered prevalence and the known PPUL in different

Externí odkaz: https://doaj.org/article/a9bb0439127f43ec9f2d9b530e243764

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Akademický článek

Preventing nerve function impairment in leprosy: validation and updating of a prediction rule.

Autor: Ron P Schuring, Jan H Richardus, Ewout W Steyerberg, David Pahan, William R Faber, Linda Oskam

Publikováno v: PLoS Neglected Tropical Diseases, Vol 2, Iss 8, p e283 (2008)

BACKGROUND: To validate and update a prediction rule for estimating the risk of leprosy-related nerve function impairment (NFI). METHODOLOGY/PRINCIPAL FINDINGS: Prospective cohort using routinely collected data, in which we determined the discriminat

Externí odkaz: https://doaj.org/article/91901f9ed44642d9beecee11b04999e8

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Immunogenicity and safety of a single booster dose of NVX-CoV2373 (TAK-019) in healthy Japanese adults who had previously received a primary series of COVID-19 mRNA vaccine: Primary analysis report of a phase 3 open-label trial

Autor: Kenji Kuriyama, Kyoko Murakami, Taisei Masuda, Kenkichi Sugiura, Sho Sakui, Ron P. Schuring, Mitsuhiro Mori

Publikováno v: Vaccine.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8fe5480490992efdf4f0fa3281836e38
https://doi.org/10.1016/j.vaccine.2023.05.001

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Safety and immunogenicity of NVX-CoV2373 (TAK-019) vaccine in healthy Japanese adults: Interim report of a phase I/II randomized controlled trial

Autor: Taisei Masuda, Kyoko Murakami, Kenkichi Sugiura, Sho Sakui, Ron P Schuring, Mitsuhiro Mori

Publikováno v: Vaccine. 40(24)

We evaluated the safety and immunogenicity of NVX-CoV2373, a recombinant SARS-CoV-2 nanoparticle vaccine, in healthy Japanese participants.This phase 1/2, randomized, observer-blind, placebo-controlled trial conducted in Japan (two sites), enrolled h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc9e9736f49ec28bc98b5f00bd37cce
https://pubmed.ncbi.nlm.nih.gov/35501178

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Protective effect of the combination BCG vaccination and rifampicin prophylaxis in leprosy prevention

Autor: David Pahan, Linda Oskam, Ron P. Schuring, Jan Hendrik Richardus

Publikováno v: Vaccine, 27(50), 7125-7128. Elsevier BV
Vaccine, 27(50), 7125-7128. Elsevier

BCG vaccination and rifampicin chemoprophylaxis are both strategies for leprosy prevention. While the combined effect is unknown, the combination may give the desired push to halt leprosy transmission. Secondary analysis was done on results from a si

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4747d6b14913a3d07090faf4f3ec43
https://doi.org/10.1016/j.vaccine.2009.09.054

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Physical Distance, Genetic Relationship, Age, and Leprosy Classification Are Independent Risk Factors for Leprosy in Contacts of Patients with Leprosy

Autor: Jan Hendrik Richardus, Linda Oskam, F. Johannes Moet, David Pahan, Ron P. Schuring

Publikováno v: Journal of Infectious Diseases, 193(3), 346-353. Oxford University Press

Background. Close contacts of patients with leprosy have a higher risk of developing leprosy. Several risk factors have been identified, including genetic relationship and physical distance. Their independent contributions to the risk of developing l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9362005e3e0aa02b8d53d89368cf86bd
https://doi.org/10.1086/499278

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Low frequency of the TIRAPS180L polymorphism in Africa, and its potential role in malaria, sepsis, and leprosy

Autor: George Bedu-Addo, Linda Oskam, Ulrich Bienzle, Ralf R. Schumann, Frank P. Mockenhaupt, Ron P. Schuring, Erkan Alpsoy, Lutz Hamann, Oliver Kumpf

Publikováno v: BMC Medical Genetics, Vol 10, Iss 1, p 65 (2009)
BMC Medical Genetics

Background The Toll-like receptors (TLRs) mediate innate immunity to various pathogens. A mutation (S180L) in the TLR downstream signal transducer TIRAP has recently been reported to be common in Europeans and Africans and to roughly half the risks o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01e086402dee28bf7dda344b4b84c269
https://doi.org/10.1186/1471-2350-10-65

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Polymorphism N248S in the human Toll-like receptor 1 gene is related to leprosy and leprosy reactions

Autor: Linda Oskam, Jan Hendrik Richardus, Ron P. Schuring, Ralf R. Schumann, David Pahan, William R. Faber, Lutz Hamann

Publikováno v: Journal of infectious diseases, 199(12), 1816-1819. Oxford University Press
Journal of Infectious Diseases, 199(12), 1816-1819. Oxford University Press

We investigated the association between a polymorphism of a key innate immunity receptor, Toll-like receptor 1 (TLR1) N248S, and susceptibility to leprosy and its clinical presentation. TLR1 N248S has been shown elsewhere to diminish TLR1 signaling a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4ef4593565a39403db6f17743d21f6
https://pubmed.ncbi.nlm.nih.gov/19456232

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Association between anti-pGL-I IgM and clinical and demographic parameters in leprosy

Autor: Jan Hendrik Richardus, David Pahan, Linda Oskam, Ron P. Schuring, F. Johannes Moet

Publikováno v: Leprosy review. 77(4)

Summary Objective To determine the risk factors and clinical significance of anti-PGL-I seropositivity. Design A large-scale sero-epidemiological study (COLEP) was carried out in northwest Bangladesh. Blood on filter paper from 1025 newly diagnosed p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb97ce0479fc606408542c8eb8cadebd
https://pubmed.ncbi.nlm.nih.gov/17343221

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