Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ron L. Prigeon"'
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 310:E774-E781
The incretin effect reflects the actions of enteral stimuli to promote prandial insulin secretion. Impairment of this measure has been proposed as an early marker of β-cell dysfunction and described in T2D, IGT, and even obesity without IGT. We soug
Autor:
Torsten P. Vahl, Ron L. Prigeon, Benedikt A. Aulinger, David A. D'Alessio, Hilary E. Wilson-Pérez
Publikováno v:
The Journal of clinical endocrinology and metabolism. 100(6)
Context: Glucagon-like peptide-1 (GLP-1) is an insulinotropic factor made in the gastrointestinal tract that is essential for normal glucose tolerance. Infusion of GLP-1 increases insulin secretion in both diabetic and nondiabetic humans. However, th
Rapid deterioration of insulin secretion in obese adolescents preceding the onset of type 2 diabetes
Autor:
Ron L. Prigeon, Patricia M. Herbers, Deborah A. Elder, Jessica G. Woo, David A. D'Alessio, Lindsey Hornung
Publikováno v:
The Journal of pediatrics. 166(3)
Objective To identify pathophysiologic changes that lead to the onset of type 2 diabetes (T2DM) in adolescents. Study design Obese adolescents with normal glucose tolerance (n = 41) were studied longitudinally over the course of 4 years with serial m
Autor:
Donna J. Koerker, Robin E. Vogel, John Eng, David A. D'Alessio, Ron L. Prigeon, John W. Ensinck, Ellen C. Laschansky
Publikováno v:
Journal of Clinical Investigation. 97:133-138
Glucagon-like peptide 1 (GLP-1) is an insulinotropic hormone released after nutrient ingestion which is known to augment insulin secretion, inhibit glucagon release, and promote insulin-independent glucose disposition. To determine the overall effect